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GLP-1 ਦਵਾਈਆਂ (ਓਜ਼ੈਂਪਿਕ, ਵੈਗੋਵੀ) ਅਤੇ ਤੁਹਾਡੀ ਸਰਜਰੀ

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If you take a GLP-1 medication (such as semaglutide — Ozempic or Wegovy) and you are having an operation: what these drugs do, why they matter for your anaesthetic (delayed stomach emptying and aspiration risk), and what you should do before surgery.

Updated Jul 2026
ਇੱਕ ਚਿਕਿਤਸਾ ਇੰਜੈਕਸ਼ਨ ਪੈਨ।
GLP-1 ਦਵਾਈਆਂ ਕ੍ਰਮਵਾਰ ਵਧ ਰਹੀਆਂ ਹਨ ਅਤੇ ਇਹਨਾਂ ਦੇ ਪ੍ਰਭਾਵਾਂ ਬਾਰੇ ਸਰਜਰੀ ਅਤੇ ਐਨਾਥੀਸੀਆ ਤੋਂ ਪਹਿਲਾਂ ਚਰਚਾ ਕਰਨਾ ਜ਼ਰੂਰੀ ਹੈ। Kieran Hirpara 4.0

ਇਹ ਪੰਨਾ ਮਸ਼ੀਨ ਦੁਆਰਾ ਅਨੁਵਾਦ ਕੀਤਾ ਗਿਆ ਹੈ ਅਤੇ ਹਾਲੇ ਤੱਕ ਕਿਸੇ ਡਾਕਟਰ ਦੁਆਰਾ ਜਾਂਚਿਆ ਨਹੀਂ ਗਿਆ। ਅੰਗਰੇਜ਼ੀ ਸੰਸਕਰਣ ਹੀ ਅਧਿਕਾਰਤ ਹੈ।

ਤੁਸੀਂ ਕੀ ਮਹਿਸੂਸ ਕਰ ਰਹੇ ਹੋ

ਸਰਜਰੀ ਦੀ ਤਿਆਰੀ ਦੌਰਾਨ ਤੁਹਾਨੂੰ ਮਹਿਸੂਸ ਹੋ ਸਕਦਾ ਹੈ ਕਿ ਤੁਹਾਡਾ ਸਰੀਰ ਵੱਖਰਾ ਲੱਗ ਰਿਹਾ ਹੈ। ਕਈ ਮਰੀਜ਼ਾਂ ਨੂੰ ਪਤਾ ਚਲਦਾ ਹੈ ਕਿ ਪ੍ਰਕਿਰਿਆ ਤੋਂ ਪਹਿਲਾਂ ਭਾਰ ਘਟਾਉਣ ਲਈ GLP-1 ਦਵਾਈਆਂ ਨੂੰ ਲੈਣਾ ਮਦਦਗਾਰ ਹੁੰਦਾ ਹੈ। ਇਸ ਨਾਲ ਸਰਜਰੀ ਆਸਾਨ ਅਤੇ ਠੀਕ ਹੋਣ ਦੀ ਪ੍ਰਕਿਰਿਆ ਸੁਚੱਜੀ ਹੋ ਸਕਦੀ ਹੈ। ਜਦੋਂ ਤੁਹਾਡਾ ਭਾਰ ਘਟਦਾ ਹੈ ਤਾਂ ਤੁਹਾਨੂੰ ਵਧੇਰੇ ਊਰਜਾ ਮਹਿਸੂਸ ਹੋ ਸਕਦੀ ਹੈ। ਹਾਲਾਂਕਿ, ਇਹ ਦਵਾਈਆਂ ਤੁਹਾਡੇ ਪੇਟ ਦੇ ਕੰਮ ਕਰਨ ਦੇ ਤਰੀਕੇ ਨੂੰ ਵੀ ਬਦਲਦੀਆਂ ਹਨ। ਇਹ ਪਾਚਨ ਨੂੰ ਧੀਮਾ ਕਰਦੀਆਂ ਹਨ। ਇਸਦਾ ਮਤਲਬ ਹੈ ਕਿ ਖਾਣਾ ਆਮ ਤੋਂ ਲੰਬੇ ਸਮੇਂ ਤੱਕ ਤੁਹਾਡੇ ਪੇਟ ਵਿੱਚ ਰਹਿੰਦਾ ਹੈ।

ਇਸ ਧੀਮੇ ਪਾਚਨ ਕਾਰਨ, ਤੁਸੀਂ ਥੋੜ੍ਹੀ ਮਾਤਰਾ ਵਿੱਚ ਖਾਣਾ ਖਾਣ ਤੋਂ ਬਾਅਦ ਬਹੁਤ ਜਲਦੀ ਭਰੇ ਹੋਏ ਮਹਿਸੂਸ ਕਰ ਸਕਦੇ ਹੋ। ਤੁਹਾਨੂੰ ਉਲਟੀਆਂ ਜਾਂ ਪੇਟ ਵਿੱਚ ਭਾਰੀਪਨ ਦੀ ਅਹਿਸਾਸ ਹੋ ਸਕਦੀ ਹੈ। ਕੁਝ ਲੋਕਾਂ ਨੂੰ ਐਸਿਡਿਟੀ ਜਾਂ ਐਸਿਡ ਰਿਫਲਕਸ ਦੀ ਸ਼ਿਕਾਇਤ ਹੁੰਦੀ ਹੈ। ਜਦੋਂ ਤੁਸੀਂ ਦਵਾਈ ਸ਼ੁਰੂ ਕਰਦੇ ਹੋ ਜਾਂ ਖੁਰਾਕ ਵਧਾਉਂਦੇ ਹੋ ਤਾਂ ਇਹ ਲੱਛਣ ਆਮ ਹੁੰਦੇ ਹਨ। ਇਹ ਅਕਸਰ ਖਾਣੇ ਤੋਂ ਬਾਅਦ ਹੁੰਦੇ ਹਨ। ਜੇਕਰ ਤੁਸੀਂ ਬਹੁਤ ਤੇਜ਼ੀ ਨਾਲ ਖਾਂਦੇ ਹੋ ਜਾਂ ਭਾਰੀ, ਚਰਬੀ ਵਾਲੇ ਖਾਣੇ ਚੁਣਦੇ ਹੋ ਤਾਂ ਤੁਹਾਨੂੰ ਅਸੁਵਿਧਾ ਮਹਿਸੂਸ ਹੋ ਸਕਦੀ ਹੈ।

ਤੁਹਾਡਾ ਸਰਜਨ ਤੁਹਾਨੂੰ ਦੱਸੇਗਾ ਕਿ ਸਰਜਰੀ ਤੋਂ ਪਹਿਲਾਂ ਇਹਨਾਂ ਦਵਾਈਆਂ ਨੂੰ ਬੰਦ ਕਰਨਾ ਹੈ ਜਾਂ ਨਹੀਂ। ਮੌਜੂਦਾ ਸਬੂਤ ਇਹਨਾਂ ਨੂੰ ਪਹਿਲਾਂ ਹੀ ਬੰਦ ਕਰਨ ਦੀ ਸਿਫਾਰਸ਼ ਨਹੀਂ ਕਰਦੇ ਕਿਉਂਕਿ ਇਸ ਨਾਲ ਖੂਨ ਵਿੱਚ ਸ਼ੱਕਰ ਦਾ ਪੱਧਰ ਵਧ ਸਕਦਾ ਹੈ ਅਤੇ ਭਾਰ ਵਾਪਸ ਆ ਸਕਦਾ ਹੈ। ਇਸਦੇ ਬਦਲੇ, ਤੁਹਾਡੀ ਦੇਖਭਾਲ ਟੀਮ ਸਮਾਂ ਸਾਵਧਾਨੀ ਨਾਲ ਨਿਯੰਤਰਿਤ ਕਰੇਗੀ। ਇਹ ਠੀਕ ਹੋਣ ਦੀ ਪ੍ਰਕਿਰਿਆ ਦੌਰਾਨ ਤੁਹਾਡੇ ਭਾਰ ਨੂੰ ਸਥਿਰ ਅਤੇ ਖੂਨ ਵਿੱਚ ਸ਼ੱਕਰ ਨੂੰ ਨਿਯੰਤਰਿਤ ਰੱਖਣ ਵਿੱਚ ਮਦਦ ਕਰਦਾ ਹੈ।

ਸਰਜਰੀ ਤੋਂ ਬਾਅਦ, ਤੁਸੀਂ ਸੋਚ ਸਕਦੇ ਹੋ ਕਿ ਇਹ ਦਵਾਈਆਂ ਤੁਹਾਡੀ ਠੀਕ ਹੋਣ ਦੀ ਪ੍ਰਕਿਰਿਆ ਨੂੰ ਕਿਵੇਂ ਪ੍ਰਭਾਵਿਤ ਕਰਦੀਆਂ ਹਨ। ਖੋਜ ਦਰਸਾਉਂਦੀ ਹੈ ਕਿ ਜੋੜਾਂ ਦੇ ਬਦਲਾਅ ਦੇ ਸਮੇਂ ਦੇ ਆਸ-ਪਾਸ GLP-1 ਦਵਾਈਆਂ ਦੀ ਵਰਤੋਂ ਨਾਲ ਪਹਿਲੇ 90 ਦਿਨਾਂ ਜਾਂ ਦੋ ਸਾਲਾਂ ਦੌਰਾਨ ਜਟਿਲਤਾਵਾਂ ਦਾ ਖਤਰਾ ਵਧਦਾ ਨਹੀਂ ਹੈ। ਅਸਲ ਵਿੱਚ, ਕੁਝ ਅਧਿਐਨਾਂ ਵਿੱਚ ਸੰਕਰਮਣ ਅਤੇ ਹਸਪਤਾਲ ਦਾ ਦੁਬਾਰਾ ਦਾਖਲਾ ਹੋਣ ਦੇ ਖਤਰੇ ਵਿੱਚ ਕਮੀ ਦਾ ਸੁਝਾਅ ਦਿੱਤਾ ਗਿਆ ਹੈ। ਤੁਸੀਂ ਤੇਜ਼ੀ ਨਾਲ ਠੀਕ ਹੋ ਸਕਦੇ ਹੋ ਅਤੇ ਹਸਪਤਾਲ ਦੇ ਸਰੋਤਾਂ ਦੀ ਘੱਟ ਵਰਤੋਂ ਕਰ ਸਕਦੇ ਹੋ।

ਹਾਲਾਂਕਿ, ਇਹ ਦਵਾਈਆਂ ਹੱਡੀਆਂ ਦੀ ਸਿਹਤ ਨੂੰ ਪ੍ਰਭਾਵਿਤ ਕਰ ਸਕਦੀਆਂ ਹਨ। ਕੁਝ ਕਿਸਮਾਂ ਹੱਡੀਆਂ ਦੇ ਟੁੱਟਣ ਦੇ ਖਤਰੇ ਨੂੰ ਵਧਾ ਸਕਦੀਆਂ ਹਨ। ਇਹਨਾਂ ਦਵਾਈਆਂ ਵਿੱਚੋਂ Exenatide ਨੂੰ ਹੱਡੀਆਂ ਦੀ ਮਜ਼ਬੂਤੀ ਲਈ ਸਭ ਤੋਂ ਸੁਰੱਖਿਅਤ ਵਿਕਲਪ ਮੰਨਿਆ ਜਾਂਦਾ ਹੈ। ਤੁਹਾਡਾ ਸਰਜਨ ਤੁਹਾਡੀਆਂ ਹੱਡੀਆਂ ਦੀ ਨਜ਼ਦੀਕੀ ਨਿਗਰਾਨੀ ਕਰੇਗਾ। ਜੇਕਰ ਤੁਹਾਨੂੰ ਓਸਟੀਓਆਰਥਰਾਈਟਿਸ (ਹੱਡੀਆਂ ਦੇ ਜੋੜਾਂ ਦਾ ਸੋਜ) ਹੈ, ਤਾਂ ਤੁਹਾਡਾ ਡਾਕਟਰ ਕਿਸੇ ਵੀ ਬਦਲਾਅ ਦੀ ਨਿਗਰਾਨੀ ਕਰੇਗਾ। ਇਹ ਯਕੀਨੀ ਬਣਾਉਂਦਾ ਹੈ ਕਿ ਜਦੋਂ ਤੁਸੀਂ ਚਾਲ-ਫਿਰਾਲ ਫਿਰ ਤੋਂ ਪ੍ਰਾਪਤ ਕਰਦੇ ਹੋ ਤਾਂ ਤੁਹਾਡੇ ਜੋੜ ਮਜ਼ਬੂਤ ਰਹਿਣ।

ਤੁਸੀਂ ਇਹਨਾਂ ਬਦਲਾਵਾਂ ਬਾਰੇ ਚਿੰਤਤ ਮਹਿਸੂਸ ਕਰ ਸਕਦੇ ਹੋ। ਇਹ ਆਮ ਗੱਲ ਹੈ ਕਿ ਤੁਸੀਂ ਦਵਾਈਆਂ ਦਾ ਸਰਜਰੀ ਨਾਲ ਕਿਵੇਂ ਪ੍ਰਤੀਕਿਰਿਆ ਹੁੰਦੀ ਹੈ ਇਸ ਬਾਰੇ ਚਿੰਤਾ ਕਰੋ। ਯਾਦ ਰੱਖੋ ਕਿ ਤੁਹਾਡੀ ਟੀਮ ਦੇ ਇਸ ਵਿੱਚ ਤਜਰਬਾ ਹੈ। ਉਹ ਤੁਹਾਡੇ ਸਰੀਰ ਅਨੁਸਾਰ ਯੋਜਨਾ ਨੂੰ ਢਾਲਣਗੇ। ਆਪਣੀ ਯਾਤਰਾ ਦੌਰਾਨ ਸੁਰੱਖਿਅਤ ਅਤੇ ਆਰਾਮਦਾਇਕ ਰਹਿਣ ਲਈ ਖਾਣ-ਪੀਣ ਅਤੇ ਦਵਾਈਆਂ ਦੇ ਸਮੇਂ ਬਾਰੇ ਉਹਨਾਂ ਦੇ ਹਦਾਇਤਾਂ ਦੀ ਪਾਲਣਾ ਕਰਨ 'ਤੇ ਧਿਆਨ ਦਿਓ।

ਅਸਲ ਵਿੱਚ ਕੀ ਹੋ ਰਿਹਾ ਹੈ

ਤੁਹਾਡਾ ਸਰੀਰ ਭਾਰ ਅਤੇ ਖੂਨ ਦੀ ਸ਼ੱਕਰ ਨੂੰ ਕੰਟਰੋਲ ਕਰਨ ਵਿੱਚ ਮਦਦ ਲਈ ਇਹਨਾਂ ਦਵਾਈਆਂ ਦੀ ਵਰਤੋਂ ਕਰ ਰਿਹਾ ਹੈ। ਇਹ ਦਵਾਈਆਂ ਤੁਹਾਡੇ ਪਾਚਨ ਤੰਤਰ ਨੂੰ ਇਸ ਤਰ੍ਹਾਂ ਕੰਮ ਕਰਨ ਲਈ ਪ੍ਰੇਰਿਤ ਕਰਦੀਆਂ ਹਨ ਕਿ ਤੁਹਾਡਾ ਪੇਟ ਭੋਜਨ ਨੂੰ ਹੌਲੀ-ਹੌਲੀ ਖਾਲੀ ਕਰਦਾ ਹੈ। ਇਸ ਨਾਲ ਤੁਹਾਨੂੰ ਲੰਬੇ ਸਮੇਂ ਤੱਕ ਭਰੇ ਹੋਣ ਦਾ ਅਹਿਸਾਸ ਹੁੰਦਾ ਹੈ ਅਤੇ ਤੁਹਾਡੇ ਸਰੀਰ ਨੂੰ ਗਲੂਕੋਜ਼ ਨੂੰ ਸੰਭਾਲਣ ਵਿੱਚ ਮਦਦ ਮਿਲਦੀ ਹੈ। ਬਹੁਤ ਸਾਰੇ ਮਰੀਜ਼ਾਂ ਲਈ, ਇਹ ਸਰਜਰੀ ਤੋਂ ਪਹਿਲਾਂ ਇੱਕ ਲਾਭਦਾਇਕ ਸਾਧਨ ਹੈ। ਇਹ ਜੋੜਾਂ ਦੇ ਬਦਲਾਅ (joint replacement) ਤੋਂ ਬਾਅਦ ਜਲਦੀ ਸੁਧਾਰ ਲਿਆ ਸਕਦਾ ਹੈ ਅਤੇ ਹਸਪਤਾਲ ਵਿੱਚ ਦੁਬਾਰਾ ਭਰਤੀ ਹੋਣ ਦੇ ਜੋਖਮ ਨੂੰ ਘਟਾ ਸਕਦਾ ਹੈ।

ਹਾਲਾਂਕਿ, ਇਹ ਹੌਲੀ ਪਾਚਨ ਤੁਹਾਡੇ ਸਰੀਰ ਦੇ ਐਨੈਸਥੀਸੀਆ ਅਤੇ ਸੁਧਾਰ ਦੀ ਪ੍ਰਕਿਰਿਆ ਨੂੰ ਸੰਭਾਲਣ ਦੇ ਤਰੀਕੇ ਨੂੰ ਬਦਲ ਦਿੰਦਾ ਹੈ। ਕਿਉਂਕਿ ਭੋਜਨ ਤੁਹਾਡੇ ਪੇਟ ਵਿੱਚ ਲੰਬੇ ਸਮੇਂ ਤੱਕ ਰਹਿੰਦਾ ਹੈ, ਸਰਜਰੀ ਦੌਰਾਨ ਪੇਟ ਦੀਆਂ ਸਮੱਗਰੀਆਂ ਦੇ ਉੱਪਰ ਆਉਣ ਦਾ ਜੋਖਮ ਵੱਧ ਜਾਂਦਾ ਹੈ। ਇਹੀ ਕਾਰਨ ਹੈ ਕਿ ਤੁਹਾਡੇ ਸਰਜਨ ਨੂੰ ਇਹ ਦੱਸਣਾ ਜ਼ਰੂਰੀ ਹੈ ਕਿ ਤੁਸੀਂ ਇਹਨਾਂ ਦਵਾਈਆਂ ਦੀ ਵਰਤੋਂ ਕਰ ਰਹੇ ਹੋ। ਇਸ ਨਾਲ ਉਹ ਤੁਹਾਡੀ ਦੇਖਭਾਲ ਨੂੰ ਸੁਰੱਖਿਅਤ ਢੰਗ ਨਾਲ ਯੋਜਨਾਬੱਧ ਕਰ ਸਕਦੇ ਹਨ। ਆਪਣੇ ਆਪ ਨਾਲ ਦਵਾਈ ਬੰਦ ਕਰਨ ਦੀ ਸਿਫਾਰਸ਼ ਨਹੀਂ ਕੀਤੀ ਜਾਂਦੀ। ਇਸ ਨਾਲ ਤੁਹਾਡੀ ਖੂਨ ਦੀ ਸ਼ੱਕਰ ਅਚਾਨਕ ਵਧ ਸਕਦੀ ਹੈ ਅਤੇ ਭਾਰ ਨੂੰ ਕੰਟਰੋਲ ਕਰਨਾ ਮੁਸ਼ਕਲ ਹੋ ਸਕਦਾ ਹੈ।

ਇਹ ਦਵਾਈਆਂ ਤੁਹਾਡੇ ਹੱਡੀਆਂ ਅਤੇ ਜੋੜਾਂ ਨਾਲ ਜਟਿਲ ਤਰੀਕੇ ਨਾਲ ਪ੍ਰਭਾਵ ਪਾਉਂਦੀਆਂ ਹਨ। ਇਹ ਕੁਝ ਮਰੀਜ਼ਾਂ ਵਿੱਚ ਹੱਡੀਆਂ ਦੇ ਨੁਕਸਾਨ ਤੋਂ ਕੁਝ ਸੁਰੱਖਿਆ ਪ੍ਰਦਾਨ ਕਰ ਸਕਦੀਆਂ ਹਨ। ਹਾਲਾਂਕਿ, ਜੋੜਾਂ ਦੀ ਸਿਹਤ 'ਤੇ ਇਹਨਾਂ ਦੇ ਲੰਬੇ ਸਮੇਂ ਦੇ ਪ੍ਰਭਾਵਾਂ ਦੀ ਹਾਲੇ ਵੀ ਜਾਂਚ ਕੀਤੀ ਜਾ ਰਹੀ ਹੈ। ਕੁਝ ਡਾਟਾ ਸੁਝਾਅ ਦਿੰਦਾ ਹੈ ਕਿ ਇਹ ਹੱਥ ਜਾਂ ਘੁਟਣ ਦੀ ਸਰਜਰੀ ਤੋਂ ਬਾਅਦ ਸੰਕਰਮਣ ਦੇ ਜੋਖਮ ਨੂੰ ਘਟਾ ਸਕਦੀਆਂ ਹਨ। ਹੋਰ ਨਤੀਜੇ ਮਿਸ਼ਰਤ ਹਨ। ਤੁਹਾਡਾ ਸਰਜਨ ਇਹਨਾਂ ਲਾਭਾਂ ਨੂੰ ਜੋਖਮਾਂ ਦੇ ਨਾਲ ਤੁਲਨਾ ਕਰੇਗਾ। ਉਹ ਚਾਹੁੰਦੇ ਹਨ ਕਿ ਤੁਹਾਡੀਆਂ ਹੱਡੀਆਂ ਅਤੇ ਜੋੜ ਤੁਹਾਡੀ ਪ੍ਰਕਿਰਿਆ ਲਈ ਜਿੰਨਾ ਸੰਭਵ ਹੋ ਸਕੇ ਮਜ਼ਬੂਤ ਹੋਣ।

ਮਕਸਦ ਤੁਹਾਨੂੰ ਸਥਿਰ ਰੱਖਣਾ ਹੈ। ਤੁਹਾਨੂੰ ਸਰਜਰੀ ਤੋਂ ਪਹਿਲਾਂ ਆਪਣੀ ਲਿਖਤੀ ਖੁਰਾਕ ਲੈਣਾ ਬੰਦ ਨਹੀਂ ਕਰਨਾ ਚਾਹੀਦਾ, ਜਦੋਂ ਤੱਕ ਤੁਹਾਡਾ ਸਰਜਨ ਤੁਹਾਨੂੰ ਨਾ ਕਹੇ। ਅਚਾਨਕ ਬਦਲਾਅ ਤੁਹਾਡੀ ਸਿਹਤ ਨੂੰ ਸਰਜਰੀ ਨਾਲੋਂ ਵੱਧ ਨੁਕਸਾਨ ਪਹੁੰਚਾ ਸਕਦੇ ਹਨ। ਤੁਹਾਡਾ ਚਿਕਿਤਸਕ ਟੀਮ ਤੁਹਾਨੂੰ ਸਭ ਤੋਂ ਵਧੀਆ ਸਮਾਂ ਦੱਸੇਗੀ। ਇਹ ਯਕੀਨੀ ਬਣਾਉਂਦਾ ਹੈ ਕਿ ਤੁਹਾਨੂੰ ਭਾਰ ਅਤੇ ਸ਼ੱਕਰ ਦੇ ਲਾਭ ਮਿਲਣ, ਬਿਨਾਂ ਸਰਜਰੀ ਦੇ ਜੋਖਮ ਨੂੰ ਵਧਾਏ।

ਤੁਹਾਨੂੰ ਕੀ ਉਮੀਦ ਕਰਨੀ ਚਾਹੀਦੀ ਹੈ

ਸਰਜਰੀ ਲਈ ਤਿਆਰ ਹੁੰਦੇ ਸਮੇਂ ਤੁਸੀਂ ਆਪਣੇ ਸਰੀਰ ਵਿੱਚ ਬਦਲਾਅ ਨੋਟ ਕਰ ਸਕਦੇ ਹੋ। GLP-1 ਦਵਾਈਆਂ ਵਜ਼ਨ ਘਟਾਉਣ ਅਤੇ ਬਲੱਡ ਸ਼ੂਗਰ ਦੇ ਨਿਯੰਤਰਣ ਵਿੱਚ ਮਦਦ ਕਰਦੀਆਂ ਹਨ। ਜੋੜਾਂ ਦੇ ਬਦਲਾਅ (joint replacement) ਤੋਂ ਬਾਅਦ ਜਲਦੀ ਠੀਕ ਹੋਣ ਲਈ ਇਹ ਸਾਧਨ ਲਾਭਦਾਇਕ ਹੋ ਸਕਦੇ ਹਨ। ਤੁਹਾਨੂੰ ਹਸਪਤਾਲ ਦੇ ਦੌਰਿਆਂ ਵਿੱਚ ਘਟੋਤੀ ਅਤੇ ਸਿਹਤ ਸੇਵਾਵਾਂ 'ਤੇ ਘੱਟ ਤਣਾਅ ਮਿਲ ਸਕਦਾ ਹੈ। ਕੁਝ ਡੇਟਾ ਅਨੁਸਾਰ, ਇਹ ਦਵਾਈਆਂ ਹਿੱਪ ਜਾਂ ਘੁਟਣ (knee) ਦੀ ਸਰਜਰੀ ਤੋਂ ਬਾਅਦ ਸੰਕਰਮਣ (infection) ਦੇ ਖਤਰੇ ਨੂੰ ਘਟਾਉਣ ਨਾਲ ਵੀ ਜੁੜੀਆਂ ਹੋਈਆਂ ਹਨ।

ਤੁਹਾਡਾ ਸਰਜਨ ਸੰਭਾਵਤ ਤੌਰ 'ਤੇ ਤੁਹਾਨੂੰ ਆਪਣੀ ਦਵਾਈ ਜਾਰੀ ਰੱਖਣ ਨੂੰ ਕਹੇਗਾ। ਸਰਜਰੀ ਤੋਂ ਪਹਿਲਾਂ ਦਵਾਈ ਬੰਦ ਕਰਨ ਦੀ ਸਿਫਾਰਸ਼ ਨਹੀਂ ਕੀਤੀ ਜਾਂਦੀ। ਇਸ ਗੱਲ ਦਾ ਕਾਫੀ ਸਬੂਤ ਨਹੀਂ ਹੈ ਕਿ ਦਵਾਈ ਬੰਦ ਕਰਨਾ ਲਾਭਦਾਇਕ ਹੈ। ਦਵਾਈ ਬੰਦ ਕਰਨ ਨਾਲ ਬਲੱਡ ਸ਼ੂਗਰ ਵਧਣ ਅਤੇ ਵਜ਼ਨ ਵਧਣ ਦਾ ਖਤਰਾ ਹੋ ਸਕਦਾ ਹੈ। ਇਸ ਨਾਲ ਤੁਹਾਡੀ ਸਿਹਤ ਦਾ ਪ੍ਰਬੰਧਨ ਕਰਨਾ ਮੁਸ਼ਕਲ ਹੋ ਜਾਂਦਾ ਹੈ। ਤੁਹਾਡੀ ਦੇਖਭਾਲ ਕਰਨ ਵਾਲੀ ਟੀਮ ਤੁਹਾਡੇ ਵਜ਼ਨ ਅਤੇ ਬਲੱਡ ਸ਼ੂਗਰ ਨੂੰ ਸਥਿਰ ਰੱਖਣਾ ਚਾਹੁੰਦੀ ਹੈ।

ਤੁਹਾਨੂੰ ਇਹ ਗੱਲ ਪਤਾ ਹੋਣੀ ਚਾਹੀਦੀ ਹੈ ਕਿ ਨਤੀਜੇ ਹਰ ਕਿਸੇ ਲਈ ਇੱਕੋ ਜਿਹੇ ਨਹੀਂ ਹੁੰਦੇ। ਇਹਨਾਂ ਦਵਾਈਆਂ 'ਤੇ ਖੋਜ ਜਾਰੀ ਹੈ। ਜਦੋਂ ਕਿ ਬਹੁਤ ਸਾਰੇ ਮਰੀਜ਼ ਚੰਗਾ ਨਤੀਜਾ ਪ੍ਰਾਪਤ ਕਰਦੇ ਹਨ, ਕੁਝ ਅਧਿਐਨਾਂ ਵਿੱਚ ਮਿਸ਼ਰਿਤ ਨਤੀਜੇ ਦਿਖਾਈ ਦਿੱਤੇ ਹਨ। ਇਹਨਾਂ ਦਵਾਈਆਂ ਨੂੰ ਸਰਜਰੀ ਦੇ ਆਸ-ਪਾਸ ਵਰਤਣ ਦੇ ਸਭ ਤੋਂ ਵਧੀਆ ਤਰੀਕੇ ਨੂੰ ਪੂਰੀ ਤਰ੍ਹਾਂ ਸਮਝਣ ਲਈ ਸਾਨੂੰ ਹੋਰ ਉੱਚ-ਗੁਣਵੱਤਾ ਵਾਲੇ ਅਧਿਐਨਾਂ ਦੀ ਲੋੜ ਹੈ।

ਹੱਡੀਆਂ ਦੀ ਸਿਹਤ ਇਸ ਤਸਵੀਰ ਦਾ ਇੱਕ ਹੋਰ ਹਿੱਸਾ ਹੈ। ਇਹ ਦਵਾਈਆਂ ਤੁਹਾਡੇ ਸਰੀਰ ਦੁਆਰਾ ਹੱਡੀਆਂ ਨਾਲ ਕਿਵੇਂ ਸਲੂਕ ਕੀਤਾ ਜਾਂਦਾ ਹੈ, ਇਸ 'ਤੇ ਅਸਰ ਪਾਉਂਦੀਆਂ ਹਨ। Exenatide (ਐਕਸੇਨਾਟਾਈਡ) ਸਮਾਨ ਵਰਗ ਦੀਆਂ ਹੋਰ ਵਿਕਲਪਾਂ ਦੀ ਤੁਲਨਾ ਵਿੱਚ ਟੁੱਟਣ (fracture) ਦੇ ਘੱਟ ਖਤਰੇ ਨਾਲ ਆ ਸਕਦੀ ਹੈ। ਕੀ ਇਹ ਦਵਾਈਆਂ ਘਸਣ-ਪਸ਼ਣ ਵਾਲੇ ਆਰਥਰਾਈਟਸ (wear-and-tear arthritis) ਦੇ ਨਵੇਂ ਕੇਸਾਂ ਨਾਲ ਜੁੜੀਆਂ ਹੋਈਆਂ ਹਨ, ਇਸ ਬਾਰੇ ਵੀ ਜਾਰੀ ਖੋਜ ਚੱਲ ਰਹੀ ਹੈ। ਇਹ ਇੱਕ ਜਟਿਲ ਖੇਤਰ ਹੈ ਜਿਸਨੂੰ ਤੁਹਾਡਾ ਸਰਜਨ ਘਨੀਸਤਾ ਨਾਲ ਨਿਗਰਾਨੀ ਵਿੱਚ ਰੱਖੇਗਾ।

ਸਮੁੱਚੇ ਤੌਰ 'ਤੇ, ਇਹਨਾਂ ਸਾਧਨਾਂ ਨਾਲ ਵਜ਼ਨ ਅਤੇ ਡਾਈਬੀਟੀਜ਼ (diabetes) ਦਾ ਪ੍ਰਬੰਧਨ ਕਰਨ ਵਾਲਿਆਂ ਲਈ ਭਵਿੱਖਬਾਣੀ ਆਮ ਤੌਰ 'ਤੇ ਸਕਾਰਾਤਮਕ ਹੈ। ਤੁਹਾਨੂੰ ਆਪਣੀ ਪ੍ਰਕਿਰਿਆ (procedure) ਵਿੱਚੋਂ ਇੱਕ ਸੁਚੱਜਾ ਰਾਹ ਤੈਅ ਕਰਨ ਲਈ ਮਿਲ ਸਕਦਾ ਹੈ। ਤੁਹਾਨੂੰ ਘੱਟ ਜਟਿਲਤਾਵਾਂ ਅਤੇ ਰੋਜ਼ਾਨਾ ਜੀਵਨ ਵਿੱਚ ਤੇਜ਼ ਵਾਪਸੀ ਦਾ ਸਾਹਮਣਾ ਕਰਨਾ ਪੈ ਸਕਦਾ ਹੈ। ਤੁਹਾਡਾ ਸਰਜਨ ਯੋਜਨਾ ਨੂੰ ਤੁਹਾਡੀਆਂ ਖਾਸ ਲੋੜਾਂ ਅਨੁਸਾਰ ਢਾਲੇਗਾ। ਆਪਣੀ ਦਵਾਈ ਨਿਰਦੇਸ਼ਾਂ ਅਨੁਸਾਰ ਜਾਰੀ ਰੱਖੋ। ਕੋਈ ਵੀ ਬਦਲਾਅ ਹੋਣ 'ਤੇ ਆਪਣੀ ਦੇਖਭਾਲ ਕਰਨ ਵਾਲੀ ਟੀਮ ਨੂੰ ਜਾਣਕਾਰੀ ਦਿੰਦੇ ਰਹੋ। ਇਹ ਦ੍ਰਿਸ਼ਟੀਕੋਣ ਤੁਹਾਡੀ ਸਰਜਰੀ ਲਈ ਸਭ ਤੋਂ ਵਧੀਆ ਸੰਭਵ ਨਤੀਜੇ ਦਾ ਸਮਰਥਨ ਕਰਦਾ ਹੈ।

Reviewed by Kieran Hirpara · 13 June 2026.

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Evidence & references

This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.

Overview

  • GLP-1 receptor agonists induce delayed gastric emptying, which has implications for perioperative aspiration risk during anesthesia [1].
  • The increasing prevalence of GLP-1 receptor agonist use in patients with obesity presents a new challenge for anesthesiologists [2].
  • High-quality studies are needed to determine optimal perioperative care for patients on GLP-1 receptor agonists [2].
  • GLP-1 receptor agonists show potential to reduce postoperative complications in total joint arthroplasty, but findings remain inconsistent [3].
  • Further research is needed to clarify the impact of GLP-1 receptor agonists on surgical outcomes and establish perioperative management guidelines [3].
  • Conflicting findings regarding the impact of GLP-1 receptor agonists on postoperative outcomes in arthroplasty highlight the need for well-designed multicenter studies and randomized controlled trials [4].
  • Arthroplasty surgeons will encounter an increasing number of patients on GLP-1 agonists, necessitating an understanding of their perioperative implications [5].
  • GLP-1 receptor agonist therapy is not associated with adverse events following shoulder surgery [6].
  • GLP-1 agonist use should not be a contraindication for proceeding with total shoulder arthroplasty [6].
  • Elective preprocedural cessation of GLP-1 receptor agonists and GLP-1/GIP receptor agonists is not recommended due to insufficient data supporting cessation and risks of hyperglycemia and compromised weight control [7].
  • Variability in available studies, potential confounding factors, and severe heterogeneity of conclusions emphasize the need for more high-quality evidence-based primary research to optimize perioperative management of patients taking GLP-1 receptor agonists [8].
  • Narrative reviews explore the mechanisms of action of GLP-1 agonists, their effects on bone health, and their implications in perioperative patients undergoing orthopedic surgery, with an emphasis on spine surgery [9].
  • Semaglutide and other GLP-1 agonists may increase the number of eligible candidates for elective total joint arthroplasty by enabling weight loss and improving diabetic control [10].
  • Semaglutide and other GLP-1 agonists may potentially reduce postoperative complications such as sepsis and prosthetic joint infections [10].
  • GLP-1 receptor agonist use suggests a potential benefit for optimizing high-risk patients with obesity or diabetes undergoing total joint arthroplasty [11].
  • GLP-1 receptor agonists may provide skeletal benefits in type 2 diabetes patients by addressing specific mechanisms underlying diabetic osteopathy [16].
  • The effects of GLP-1 receptor agonists on diabetic osteopathy vary by agent type, patient characteristics, and treatment duration [16].
  • Further investigation is needed to elucidate the association between GLP-1 receptor agonist use and the increased incidence of osteoarthritis diagnosis and conversion to total knee arthroplasty in patients with no preexisting osteoarthritis [19].

Effects on Surgery and Recovery

  • Interdisciplinary collaboration between endocrinologists and anesthesiologists is important to ensure safe and individualized perioperative management of patients on GLP-1 RAs [1].
  • High-quality studies are needed to address the optimal perioperative care of patients on GLP-1RAs [2].
  • Further research is needed to clarify the impact of GLP-1 receptor agonists on outcomes and establish perioperative management guidelines for total joint arthroplasty [3].
  • Conflicting findings regarding the effects of GLP-1 RAs on surgical outcomes highlight the need for well-designed multicenter studies and randomized controlled trials [4].
  • GLP-1 agonist use should not be a contraindication for proceeding with total shoulder arthroplasty (TSA) [6].
  • Elective preprocedural cessation of GLP-1RAs and GLP-1/GIPRAs is not recommended due to insufficient data supporting cessation and risks of hyperglycemia and compromised weight control [7].
  • Variability in available studies, potential confounding factors, and severe heterogeneity of conclusions emphasize the need for more high-quality evidence-based primary research to optimize perioperative management of patients taking GLP-1 RAs [8].
  • Semaglutide and other GLP-1 agonists may reduce postoperative complications such as sepsis and prosthetic joint infections in total joint arthroplasty [10].
  • GLP-1RA use has a potential benefit for optimizing high-risk patients with obesity or diabetes undergoing total joint arthroplasty [11].
  • Preoperative glucagon-like peptide-1 receptor agonist use may be linked to reduced readmission risk following joint arthroplasty [12].
  • Preoperative glucagon-like peptide-1 receptor agonist use is not associated with evidence of increased postoperative medical harm following joint arthroplasty [12].
  • Current observational data suggest that perioperative GLP-1 RA use in patients undergoing total hip or knee arthroplasty is not associated with a consistent increase in short-term revision rates [13].
  • Perioperative GLP-1 RA use in patients undergoing total hip or knee arthroplasty may be associated with a reduced risk of postoperative infection [13].
  • Extended GLP-1 RA withholding, 24-hour clear liquid diets, and pre-procedural gastric POCUS may be associated with reduced residual gastric content in selected patient populations [14].
  • Perioperative GLP-1RA use was associated with a small yet statistically significant reduction in the odds of wound dehiscence following carpal tunnel release (CTR) [15].
  • Perioperative GLP-1RA use did not increase the odds of any other 90-day postoperative complications following carpal tunnel release [15].
  • Exenatide is the best option agent with regard to the risk of fracture among GLP-1 receptor agonists [17].
  • GLP-1 receptor agonists are a promising tool for preoperative weight loss in patients with obesity and type-2 diabetes mellitus undergoing orthopaedic surgery [18].

Practical Considerations

  • The increasing prevalence of GLP-1 RA use in patients with obesity presents a new challenge for anesthesiologists regarding perioperative care [2].
  • High-quality studies are needed to address the optimal perioperative care of patients on GLP-1 RAs [2].
  • Further research is needed to clarify the impact of GLP-1 RAs on outcomes and establish perioperative management guidelines for total joint arthroplasty [3].
  • Conflicting findings regarding the effects of GLP-1 RAs on surgical outcomes highlight the need for further research, including well-designed multicenter studies and randomized controlled trials [4].
  • Elective preprocedural cessation of GLP-1 RAs and GLP-1/GIP RAs is not recommended due to insufficient data supporting cessation and the risks of hyperglycemia and compromised weight control [7].
  • Narrative reviews explore the mechanisms of action of GLP-1 agonists, their effects on bone health, and their implications for perioperative patients undergoing orthopedic surgery, with an emphasis on spine surgery [9].
  • GLP-1 RA use may benefit high-risk patients with obesity or diabetes undergoing total joint arthroplasty [11].
  • Preoperative GLP-1 receptor agonist use may be linked to reduced readmission risk following joint arthroplasty [12].
  • Preoperative GLP-1 receptor agonist use is not associated with evidence of increased postoperative medical harm in joint arthroplasty [12].

Key Evidence

  • [L4] This review summarizes the pharmacological mechanisms and clinical implications of GLP-1 RA-induced delayed gastric emptying, evaluates current literature on perioperative aspiration risk, and emphasizes the importance of interdisciplinary collaboration between endocrinologists and anesthesiologists to ensure safe and individualized perioperative management. [1] (10.3904/kjim.2025.277)
  • [L4] Due to the increasing popularity of GLP-1RAs in patients with obesity, the authors call for further high-quality studies to address the optimal perioperative care of patients on GLP-1RAs. [2] (10.5114/ait/203167)
  • [L5] The paper concludes that while GLP-1 receptor agonists show potential to reduce postoperative complications in total joint arthroplasty, findings remain inconsistent, and further research is needed to clarify their impact on outcomes and establish perioperative management guidelines. [3] (10.1016/j.arth.2025.10.027)
  • [L4] However, conflicting findings highlight the need for further research, particularly well-designed multicenter studies and randomized controlled trials, to clarify the effects of GLP-1 RAs on surgical outcomes. [4] (10.1016/j.arth.2025.07.015)
  • [L5] Arthroplasty surgeons will encounter an increasing number of patients on GLP-1 agonists, making it important to understand the implications of their use in the perioperative period. [5] (10.1016/j.arth.2023.12.002)
  • [L1] Based on this data, GLP-1 agonist use should not be a contraindication for proceeding with TSA. [6] (10.1016/j.jse.2025.12.005)
  • [L2] The variability in available studies, potential confounding factors, and the severe heterogeneity of conclusions all emphasize the need for more high-quality evidence-based primary research to optimize perioperative management of patients taking GLP-1 RAs. [8] (10.1186/s13741-026-00662-9)
  • [L4] This narrative review explores the mechanisms of action of GLP-1 agonists, their effects on bone health, and the implications of their use in perioperative patients undergoing orthopedic surgery, with an emphasis on spine surgery. [9] (10.1177/15563316261438492)
  • [L5] Semaglutide and other GLP-1 agonists may increase the number of eligible candidates for elective total joint arthroplasty by enabling weight loss and improving diabetic control, while also potentially reducing postoperative complications such as sepsis and prosthetic joint infections. [10] (10.1016/j.arth.2023.12.014)
  • [L1] These findings suggest a potential benefit of GLP-1RA use for optimizing high-risk patients who have obesity or diabetes undergoing total joint arthroplasty. [11] (10.1016/j.arth.2025.09.054)
  • [L1] Preoperative glucagon-like peptide-1 receptor agonist use may be linked to reduced readmission risk following joint arthroplasty, without evidence of increased postoperative medical harm. [12] (10.1016/j.arth.2025.11.036)
  • [L4] Current observational data suggest that perioperative GLP-1 RA use in patients undergoing total hip or knee arthroplasty is not associated with a consistent increase in short-term revision rates and may be associated with a reduced risk of postoperative infection. [13] (10.1186/s42836-026-00375-w)
  • [L4] Available observational evidence suggests that extended GLP-1 RA withholding, 24-hour clear liquid diets, and pre-procedural gastric POCUS may be associated with reduced residual gastric content in selected patient populations. [14] (10.7759/cureus.108216)
  • [L3] Perioperative GLP-1RA use was associated with a small yet statistically significant reduction in the odds of wound dehiscence following CTR and did not increase the odds of any other 90-day postoperative complications. [15] (10.1016/j.jhsg.2025.100746)
  • [L1] GLP-1 RAs may provide skeletal benefits in T2DM patients by addressing specific mechanisms underlying diabetic osteopathy, with effects varying by agent type, patient characteristics, and treatment duration. [16] (10.1186/s12891-025-09022-y)
  • [L1] Exenatide is the best option agent with regard to the risk of fracture. [17] (10.1007/s00198-018-4649-8)
  • [L5] GLP-1 receptor agonists are a promising tool for preoperative weight loss in patients with obesity and type-2 diabetes mellitus undergoing orthopaedic surgery. [18] (10.2106/jbjs.24.01287)
  • [L3] Further investigation is needed to elucidate the association between GLP-1-RA use and the increased incidence of OA diagnosis and conversion to TKA in patients with no preexisting OA. [19] (10.1177/23259671241297157)

References

[1] Delayed gastric emptying induced by glucagon-like peptide-1 receptor agonists and its implications for perioperative risk during anesthesia. The Korean Journal of Internal Medicine. 2026. DOI: 10.3904/kjim.2025.277

[2] GLP-1 agonists: a new hope for patients, a new challenge for anaesthetists. Anaesthesiology Intensive Therapy. 2025. DOI: 10.5114/ait/203167

[3] Glucagon-Like Peptide-1 Receptor Agonists: Have We Found the Holy Grail for Total Joint Arthroplasty?. The Journal of Arthroplasty. 2025. DOI: 10.1016/j.arth.2025.10.027

[4] Impact of Glucagon-Like Peptide-1 Receptor Agonists on Postoperative Outcomes in Arthroplasty: A Systematic Review. The Journal of Arthroplasty. 2025. DOI: 10.1016/j.arth.2025.07.015

[5] The Impact of Glucagon-Like Peptide-1 Agonists on Hip and Knee Arthroplasty and Perioperative Considerations. The Journal of Arthroplasty. 2024. DOI: 10.1016/j.arth.2023.12.002

[6] GLP-1 receptor agonist therapy is not associated with adverse events following shoulder surgery: a systematic review and meta-analysis. Journal of Shoulder and Elbow Surgery. 2026. DOI: 10.1016/j.jse.2025.12.005

[7] Periprocedural use of GLP-1 receptor agonists: ANZCA Clinical Practice Recommendations. ANZCA. 2025.

[8] Perioperative anesthesia management of GLP-1 receptor agonists: a systematic review of potential risks. Perioperative Medicine. 2026. DOI: 10.1186/s13741-026-00662-9

[9] GLP-1 Agonists in Orthopedic Surgery: A Narrative Review of Bone Health and Surgical Implications. HSS Journal. 2026. DOI: 10.1177/15563316261438492

[10] Semaglutide and Other GLP-1 Agonists: A Boon for the Arthroplasty Industry?. The Journal of Arthroplasty. 2024. DOI: 10.1016/j.arth.2023.12.014

[11] The Impact of Glucagon-Like Peptide-1 Receptor Agonist Use on Clinical Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis of 346,899 Patients. The Journal of Arthroplasty. 2025. DOI: 10.1016/j.arth.2025.09.054

[12] Glucagon-Like Peptide-1 Receptor Agonists, Readmission, and Postoperative Complications in Arthroplasty: A Systematic Review and Meta-Analysis. The Journal of Arthroplasty. 2025. DOI: 10.1016/j.arth.2025.11.036

[13] Glucagon-like peptide-1 receptor agonists in total joint arthroplasty: a comprehensive systematic review of what orthopaedic surgeons should know. Arthroplasty. 2026. DOI: 10.1186/s42836-026-00375-w

[14] Peri-Procedural Fasting and Gastric Ultrasound Strategies in Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Users: A Systematic Review With Qualitative Synthesis. Cureus. 2026. DOI: 10.7759/cureus.108216

[15] Impact of Perioperative Glucagon-Like Peptide-1 Receptor Agonists on Postoperative Outcomes Following Carpal Tunnel Release. Journal of Hand Surgery Global Online. 2025. DOI: 10.1016/j.jhsg.2025.100746

[16] Differential effects of GLP-1 receptor agonists on diabetic osteopathy in type 2 diabetes: a patient-stratified network meta-analysis. BMC Musculoskeletal Disorders. 2025. DOI: 10.1186/s12891-025-09022-y

[17] Glucagon-like peptide-1 receptor agonists and fracture risk: a network meta-analysis of randomized clinical trials. Osteoporosis International. 2018. DOI: 10.1007/s00198-018-4649-8

[18] GLP-1 Receptor Agonists in Orthopaedic Surgery: Implications for Perioperative Care and Outcomes. Journal of Bone and Joint Surgery. 2025. DOI: 10.2106/jbjs.24.01287

[19] The Impact of Contemporary Glucagon-like Peptide-1 Receptor Agonists on the Onset, Severity, and Conversion to Arthroplasty in Hip and Knee Osteoarthritis. Orthopaedic Journal of Sports Medicine. 2025. DOI: 10.1177/23259671241297157

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