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This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.

Overview¶

Pediatric and Adolescent Management¶

• Radial osteotomies are effective in improving short-term clinical outcomes and radiographic findings in teenage patients with Kienböck disease [3].
• Good and excellent clinical and radiological outcomes can be achieved with both nonsurgical and surgical treatments in skeletally immature patients with Kienböck disease [6].
• A prospective investigation is needed to delineate the appropriate management and expected outcomes of pediatric and adolescent Kienbock disease [7].
• Children, adolescents, and elderly patients with Kienböck disease respond well to nonoperative treatments, and this should be considered before any surgical intervention [12].
• Temporary scaphotrapezoidal joint fixation is recommended for the surgical treatment of adolescent Kienböck's disease [13].

Advanced Disease and Salvage Procedures¶

• Functional outcomes in medium-term follow-up are discouraging after scaphocapitate arthrodesis for advanced stages of Kienböck disease [2].
• The long-term clinical benefits of scaphocapitate arthrodesis for treatment of collapsed Kienböck disease are demonstrated [8].
• Radial shortening osteotomy for symptomatic Kienböck's disease yields reasonable long-term function, though approximately one in eight patients underwent salvage surgery [9].
• Radial shortening osteotomy should not be contraindicated in advanced Kienbock's disease (without radiocarpal osteoarthritis) as it achieves long-lasting good clinical results with very few complications [11].
• Tendon ball arthroplasty in advanced Kienböck's disease results in long-term satisfactory clinical outcomes, despite widespread changes in the bones and joints within the wrist [17].
• Radial shortening osteotomy offers at least comparable outcomes with proximal row carpectomy in treating Kienböck's disease, particularly in preserving joint function and patient satisfaction [26].

Anatomy & Pathophysiology¶

Lunate Vascular Anatomy¶

• The lunate typically receives arterial contributions from branches entering both dorsally and palmarly [14].
• In one study, the lunate was supplied by only a single palmar artery in 7% of wrists [14].
• Intraosseous branching patterns vary, with 31% of specimens in one study showing a single path through the bone without significant arborization [14].
• A lunate with a single vessel and minimal branching may be at increased risk of osteonecrosis after hyperflexion or hyperextension injuries or a minimally displaced fracture [14].
• Lunate dislocation can occur without the development of osteonecrosis because the lunate usually dislocates palmarly with a flap of palmar capsule still attached, which transmits sufficient vascular supply to maintain viability [14].
• Lee (1963) found in cadaver experiments that the lunate had three predictable vascular patterns [42].

Etiology and Pathogenesis¶

• The exact mechanism(s) of Kienböck disease have not been established [1, 20].
• Mechanical factors described as having an influence in the development of Kienböck disease include ulnar variance, radial inclination, lunate morphology, intraosseous trabecular anatomy, ulnar length, lunate size, and repeated trauma [20].
• Vascular or biological factors postulated to favour the disease include a single arterial supply to the bone, poor intraosseous anastomoses, or a hypercoagulability status [20].
• The main aetiopathogenic theory is that repeated stresses to the lunate may induce a raised intraosseous pressure, which causes cessation of arterial blood flow and leads to hypoperfusion [20].
• This situation is similar to a bony "intracompartmental syndrome" and may cause progressive ischaemia, leading to interstitial oedema and necrosis of marrow fat [20].
• The pathogenesis of the disease cannot be attributed to one single cause; it seems more likely that a combination of risk and triggering factors is required [20].
• Disruption of venous outflow has been suggested as a cause of Kienböck disease [14].
• In vitro intraosseous pressure measurements within normal and necrotic lunates showed marked increases in pressure in the necrotic bones, a finding more consistent with venous stasis than with arterial compromise [14].
• It is unclear whether increased intraosseous pressure is a cause or a result of the disease process [14].
• Some believe that unrecognized and untreated fractures of the lunate lead to Kienböck's disease, based on cadaveric work by Verdan who observed that resulting fractures were not visible on standard radiographs but only on histology [61].
• Others have questioned these findings, with one study suggesting that early venous congestion, not fracture, of the lunate was responsible for the pathogenesis of Kienböck's disease [61].
• Kienböck disease is more common in patients with an ulnar minus variant [61].
• Ulter negative variance is a risk factor for Kienböck disease [33, 34].
• Decreased radial inclination is a risk factor for Kienböck disease [33, 34].
• Repetitive trauma is a risk factor for Kienböck disease [33, 34].
• Vascular patterns of the lunate are a risk factor for Kienböck disease [33, 34].
• Kienböck disease is most common in young men [33, 34].
• Kienböck disease manifests as atraumatic dorsal wrist pain and decreased grip strength [33, 34].
• Unexplained dorsal wrist pain in a young adult with negative ulnar variance should prompt magnetic resonance imaging (MRI) evaluation [33, 34].
• Kienböck disease is suspected in the face of central dorsal pain at the wrist, over the lunate [36].
• Kienböck disease often appears spontaneously, even if more or less intense or repeated injury events can be put forward [36].
• Patients with Kienböck disease often have limited mobility and grip strength [36].
• Kienböck disease is a progressive disease process that can lead to wrist pain and dysfunction [41].
• Anatomic, mechanical, vascular, and traumatic factors have been suggested to contribute to the disease [41].
• The natural history of Kienböck disease is unknown [41].
• Radiographic and clinical findings do not always correlate in Kienböck disease [41].
• Kienböck's disease is an eponym for idiopathic avascular osteonecrosis of the lunate [61].
• It usually has an insidious onset without a history of injury [61].
• Diagnosis is sometimes made after a simple fall that fractures the necrotic bone [61].
• Osteonecrosis may be the result of interruption of the vascular supply to the lunate, which shows no radiographic evidence of injury until sclerosis and osteochondral collapse [61].
• The lunate necrosis after perilunate dislocation is probably due to impairment of the arterial vasculature [61].

Carpal Anatomy and Biomechanics¶

• The wrist includes the distal radioulnar, radiocarpal, and ulnocarpal joints and the eight carpal bones and their proximal and distal articulations and attached ligaments [44].
• The eight carpal bones include the scaphoid, lunate, triquetrum, and pisiform in the proximal row and the trapezium, trapezoid, capitate, and hamate in the distal row [44].
• The radiocarpal joints are formed by the articulation of the distal radius with the scaphoid and lunate through their respective concave facets on the distal radius and the triquetrum on the triangular fibrocartilage [44].
• The distal concave articular surfaces of the proximal carpal row form the midcarpal articulations with the distal row [44].
• The distal ulnar convexity articulates at the lesser sigmoid notch of the distal radius [44].
• There is about a 20-degree inclination of the distal ulna at its articulation with the radius [44].
• The triangular fibrocartilage complex (TFCC) attaches to the ulnar margin of the lunate fossa of the radius and includes the ulnar collateral ligament, dorsal and volar radioulnar ligaments, articular disc, meniscal homologue, extensor carpi ulnaris sheath, and ulnolunate and ulnotriquetral ligament [44].
• The space of Poirier is a relatively thin area on the palmar side of the carpus, between the radiolunotriquetral ligament and the radioscapocapitate ligament, overlying the palmar surface of the lunate [44].
• The distal radius has three articular components: distally the scaphoid and lunate fossae, and medially the sigmoid notch [50].
• Between the scaphoid and the lunate fossa is a ridge that corresponds with the scapholunate interval [50].
• The concave elliptical distal radius is oriented in the sagittal plane with an average of 11 degrees of volar tilt [50].
• In the frontal plane, the average radial inclination is 23 degrees [50].
• Radial length is measured from the tip of the radial styloid to the ulnar articular surface and averages 13 mm [50].
• The radius bears 80% of the axial load transmitted through the radiocarpal joint, while the ulna bears 20% in neutral ulnar variance [51].
• The proximal row of carpal bones form an intercalated segment between the distal carpal row and the distal radius and are bound into a functional unit by the scapholunate interosseous ligament (SLIL) and lunotriquetral interosseous ligament (LTIL) [51].
• The distal row is rigid, with little motion between its bones due to stout intercarpal ligaments, and thus they act as a functional unit with the scaphoid bridging both rows [51].
• During wrist flexion from neutral, the proximal row translates dorsally [51].
• During wrist extension from neutral, the proximal row translates palmarly [51].
• The scapholunate interosseous ligament (SLIL) is the major stabilizer of the wrist and the most commonly injured wrist ligament [51].
• The SLIL is C-shaped, consisting of dorsal, palmar, and interosseous portions, with the dorsal portion being the strongest and thickest [51].
• The SLIL provides a flexion force on the lunate given its attachment to the scaphoid [51].
• The lunotriquetral interosseous ligament (LTIL) is C-shaped, where the volar portion is the thickest and strongest [51].
• The LTIL provides an extension moment on the lunate given its attachment to the triquetrum [51].
• The space of Poirier is an area adjacent to the proximal capitate without ligamentous attachment, situated ulnar to the radioscaphocapitate ligament and radial to the long radiolunate in the floor of the carpal tunnel [51].
• The space of Poirier is a weak area that is vulnerable to instability; the distal carpal row separates from the lunate through this space during a perilunate dislocation [51].

Disease Progression and Carpal Instability¶

• Fragmentation of the lunate results in loss of the mechanical strength of the central column and proximal migration of the capitate [58].
• Proximal migration of the capitate slackens the radioscaphocapitate (RSC) and scaphocapitate (SC) ligaments and leads to kinematic disruption of the carpus [58].
• In such circumstances, the loaded scaphoid is apt to follow its natural tendency and progressively collapse into flexion, an example of adaptive carpal instability [58].
• Rarely does Kienböck disease demonstrate scapholunate gap, dorsal intercalated segment instability (DISI), or dorsal translation of the scaphoid, which are pathognomonic findings of dissociative instability [58].
• One of the prognostic factors of Kienböck disease is the absence (stage 3A) or presence (stage 3B) of abnormal flexion and pronation deformity of the scaphoid [58].
• In stage 3A, the carpus remains relatively stable, whereas in stage 3B, it has collapsed [58].
• DISI can be caused by Kienböck disease [65].
• In DISI, the lunate extends with midcarpal flexion because the lunate remains connected to the triquetrum through the LTIL, while the scaphoid cannot exert its normal flexion movement [65].

Classification¶

Osseous Staging (Lichtman)¶

• The Lichtman classification for Kienböck's disease has good reliability and reproducibility [43].
• Stage III of Kienböck disease is the most common stage at initial presentation [37].
• Lichtman Stage IIIA is defined by lunate fragmentation without changes in carpal alignment [37].
• Lichtman Stage IIIB is defined by lunate fragmentation associated with fixed anterior flexion of the scaphoid, proximal migration of the capitate, and loss of carpal height [37].
• Lunate collapse and the appearance of radiocarpal or midcarpal degenerative arthritis occur in Lichtman Stage IV [37].
• The diagnosis of Kienböck disease in the precollapse stages is not well defined, as evidenced by substantial interobserver variability [29].
• Traditional radiographic indices measured on plain radiographs have poor diagnostic performance in the detection of carpal collapse in Kienböck's disease [16].
• High-resolution computed tomography has been shown to be more accurate than conventional radiography in the assessment of the osseous microstructure of the lunate in Kienböck disease [39].
• Assessment of the internal osseous structure and integrity of the lunate is often not possible by conventional radiography owing to superimposition of other information in the image [39].

Vascular Staging¶

• A separate vascular classification for Kienböck disease was developed by Schmitt et al. [39].
• The Schmitt classification is one of three existing classifications (osseous, vascular, cartilage) that Lichtman et al. recently combined into a unified classification and treatment algorithm [39].

Articular Cartilage Staging¶

• A separate cartilage classification for Kienböck disease was developed by Bain and Begg [39].
• The Bain and Begg arthroscopic classification provides a high probability of good long-term relief of pain and a minimal chance of requiring a salvage procedure when used for an articular-based approach to treatment [67].
• Contrary to current classifications, the articular cartilage of the lunate degenerates in early stages of Kienböck disease [5].

Unified Classification and Treatment Algorithms¶

• Lichtman et al. recently developed a unified classification and treatment algorithm combining the osseous, vascular, and cartilage classifications [39].
• The unified classification and treatment algorithm coordinates osseous, vascular, and articular data alongside patient age to allow for more precise and individualized treatment plans [24].
• A new treatment algorithm has been proposed that integrates traditional osseous classification with perfusion/viability and articular cartilage-based classifications [46].
• Bone morphology is particularly important for choosing the most appropriate treatment in Kienböck disease, specifically for determining surgical treatment decisions from stage III and IV [39].

Clinical Presentation¶

• Kienböck disease is suspected clinically in the presence of central dorsal pain at the wrist over the lunate [36].
• The onset of Kienböck disease often appears spontaneously, although more or less intense or repeated injury events may be present [36].
• Patients with Kienböck disease often exhibit limited mobility and grip strength [36].
• Clinical examination can suggest the presence of Kienböck disease but cannot confirm the diagnosis [36].
• Dorsal wrist swelling is a common manifestation of Kienböck disease and constitutes part of the pathology [53].
• The diagnosis of Kienböck disease in precollapse stages is not well defined, as evidenced by substantial interobserver variability [29].
• Traditional radiographic indices measured on plain radiographs have poor diagnostic performance in detecting carpal collapse in Kienböck disease [16].
• Lunate morphology may affect the severity of Kienböck disease at the time of initial presentation [10].

Investigations¶

Imaging Modalities and Diagnostic Performance¶

• High-resolution computed tomography (CT) is more accurate than conventional radiography in assessing the osseous microstructure of the lunate in Kienböck disease [39].
• Computed tomography of the lunate in Kienböck disease is an important investigative tool [66].
• Proton density–weighted MRIs reflected the extent and localization of the necrotic area in Kienböck-diseased lunates, as evidenced by comparison with histological analyses of the lunate specimens [70].
• Fast-field echo images using a 47-mm microscopy coil did not reflect the extent and localization of the necrotic area in Kienböck-diseased lunates when compared with histological analyses [70].
• MRI is the modality of choice for imaging radiographically occult fractures of the hand and wrist [52].
• The primary advantages of MRI compared with CT and radiography are improved tissue characterization, especially of soft tissues such as ligamentous structures and synovium, and the lack of ionizing radiation [52].
• Dynamic contrast enhancement has been used with inconsistent results to assess for the presence of avascular necrosis in the lunate or scaphoid after injury [52].
• 3T MRI is much preferred for hand and wrist imaging, especially for imaging small fields of view [52].

Staging and Classification¶

• The lunate consists of osseous, vascular, and cartilaginous components, for each of which a separate classification has been developed: osseous (Lichtman), vascular (Schmitt), and cartilage (Bain) [39].
• Lichtman et al. recently developed a unified classification and treatment algorithm combining the three existing classifications [39].
• Bone morphology is particularly important for choosing the most appropriate treatment in Kienböck disease, particularly for surgical decisions from stage III and IV [39].
• The authors propose a unified classification and treatment algorithm that coordinates osseous, vascular, and articular data alongside patient age to allow for more precise and individualized treatment plans for Kienböck disease [24].

Radiographic Progression and Indices¶

• Radiographic progression of Kienböck disease over 1 year or more seems slight on average regardless of treatment [21].
• There were no differences in changes in carpal height ratio, Stahl index, and carpal angles between patients who had radial shortening osteotomy and those who had nonsurgical treatment [21].
• Nearly half of the patients had no decrease in the carpal height ratio and/or the Stahl index over a minimum 1-year interval [21].
• Kienböck's disease progresses substantially faster than previously described [5].

Treatment¶

General Principles and Non-Operative Management¶

• The natural history of Kienböck's disease is generally considered a progressive condition that can end in Stage IV changes [4].
• Treatment strategies for Kienböck's disease focus on biomechanical unloading, vascularized bone grafts, or salvage procedures depending on the stage [4].
• There is limited, low-quality evidence that surgical treatment slows progression of Kienböck's disease [56].
• Many uncontrolled case series document slight improvement in motion and grip after surgical treatment without clear evidence that this is better than placebo or no intervention [56].

Operative: Joint-Leveling and Osteotomies¶

• The Lichtman classification directs treatment for Kienböck disease [33, 34].
• First-line surgical treatment for Kienböck disease includes a joint-leveling procedure or core decompression of the radius [33, 34].
• Radial shortening osteotomy is indicated for patients with ulnar-negative variance [33, 34].
• Radial shortening osteotomy provides decade-long improvement in 75% of patients and seems to be a reasonable treatment for symptomatic Kienböck’s disease [19].
• Radial shortening osteotomy offers at least comparable outcomes with proximal row carpectomy (PRC) in treating Kienböck's disease, particularly in preserving joint function and patient satisfaction [26].
• Capitate shortening is a safe and effective approach for treatment of the early stages of Kienböck's disease and can be associated with a satisfying outcome [45].

Operative: Vascularized Bone Grafting¶

• Supplemental vascularized bone grafting is described as part of the first-line surgical treatment for Kienböck disease [33, 34].
• Vascularized bone grafting for stage III Kienböck disease demonstrated favorable long-term results and is recommended as a surgical treatment [15].
• The treatment of Kienböck disease with vascularized bone graft from the dorsum of the radius has encouraging results and needs no other additional procedures [73].
• Vascularized grafts in general have demonstrated satisfactory clinical results in Kienböck disease, with excellent pain relief and improvement in range of motion and strength [64].
• Improved results were found in postoperative grip strength, pain relief, and function when a vascularized graft was combined with 4 months’ temporary scaphocapitate (SC) pinning [64].
• For Kienböck disease without collapse or injury to the articular surfaces, 5 plus 4 ECA grafts are currently considered a primary option [68].
• Osteochondral MFT flaps may prove to be a useful option to replace fragmented and very small proximal pole scaphoid nonunions and proximal lunate bone and cartilage in Kienböck cases, as an alternative to more common salvage procedures [68].
• The osteochondral, or MFT, flap has been used for replacement of the majority of the lunate, including the proximal articular surface [64].
• In a series of 16 patients treated with MFT flaps for lunate replacement, all but 1 patient had a good clinical result [64].
• In a series of 16 patients treated with MFT flaps for lunate replacement, radiographic changes demonstrated either no further collapse or improvement in lunate and carpal height over time in 14 of 16 patients [64].

Operative: Arthroscopic Procedures¶

• Arthroscopic lunate core decompression appears to be an effective and safe surgery for treating Kienböck disease on the basis of mid-term follow-up [59].

Operative: Arthrodesis and Salvage Procedures¶

• For Stage IIIB Kienböck disease, a salvage procedure for associated carpal instability and/or degenerative osteoarthritis is proximal row carpectomy (PRC) [33, 34].
• Scaphocapitate arthrodesis is an effective procedure for treatment of Kienböck disease associated with satisfactory functional outcomes and significant improvement in pain scores and grip strength [25].
• Nonetheless, functional outcomes in medium-term follow-up are discouraging after scaphocapitate arthrodesis for advanced stages of Kienböck disease [2].
• Scaphocapitate arthrodesis should be considered as a treatment option for wrist salvage in the patient with advanced Kienbock's disease [79].
• In scaphocapitate arthrodesis for Kienböck disease, debate remains regarding whether to remove the lunate, with a preference stated to not remove it [69].
• Studies have demonstrated successful pain relief is achieved without excision of the lunate in scaphocapitate arthrodesis for Kienböck disease [69].
• Expected outcomes for scaphocapitate arthrodesis include 50% to 60% range of motion in comparison to the opposite wrist [69].
• Expected outcomes for scaphocapitate arthrodesis include 80% grip strength [69].
• The nonunion rate for scaphocapitate arthrodesis is 15% [69].
• Minimum recovery time before sports participation after scaphocapitate arthrodesis is 3 months [69].
• Longer-term studies of outcome for scaphocapitate arthrodesis have demonstrated rates of progression of radioscaphoid arthritis between 9% and 50% [69].
• Progression of radioscaphoid arthritis after scaphocapitate arthrodesis has not proven to be predictably clinically relevant [69].
• Patients who smoke have a higher likelihood of nonunion after scaphocapitate arthrodesis [69].

Operative: Adolescent-Specific Procedures¶

• Surgical management of Kienböck's disease in adolescent patients can yield satisfactory outcomes in those that fail conservative management [28].

Complications¶

• Kienböck disease is a progressive condition that can end in Stage IV changes [4].
• The articular cartilage of the lunate degenerates in early stages of Kienböck disease [5].
• Approximately one in eight patients undergoing radial shortening osteotomy for symptomatic Kienböck's disease underwent salvage surgery [9].
• Scaphocapitate arthrodesis for advanced stages of Kienböck disease yields discouraging functional outcomes in medium-term follow-up [2].

Recovery¶

• Kienböck's disease is generally considered a progressive condition that can end in Stage IV changes [4].
• Contrary to current classifications, the articular cartilage of the lunate degenerates in early stages of Kienböck's disease [5].
• In a study comparing radial shortening osteotomy to nonsurgical treatment, there were no differences in changes to carpal height ratio and Stahl index between the two groups [21].
• Nearly half of patients with Kienböck disease had no decrease in the carpal height ratio and/or the Stahl index over a minimum 1-year interval [21].
• Radial shortening osteotomy provides decade-long improvement in 75% of patients with symptomatic Kienböck's disease [19].
• Radial shortening osteotomy for symptomatic Kienböck's disease yields reasonable long-term function [9].
• The medium- and long-term results of radial shortening osteotomy for Kienböck's disease in patients with negative ulnar variance are comparable to short-term results [35].
• Radial shortening osteotomy for Kienböck's disease in patients with negative ulnar variance provides long-lasting pain relief [35].
• Radial osteotomies are effective in improving short-term clinical outcomes in teenage patients with Kienböck disease [3].
• Radial osteotomies are effective in improving radiographic findings in teenage patients with Kienböck disease [3].
• Vascularized bone grafting for stage III Kienböck disease demonstrated favorable long-term results [15].
• Free vascularized iliac bone grafting for Kienböck's disease results in clinical and radiological improvements that last for a long period of time [22].
• The longer-term results of titanium lunate arthroplasty for stage III Kienböck disease are promising [31].
• Tendon ball arthroplasty in advanced Kienböck's disease results in long-term satisfactory clinical outcomes [17].
• Tendon ball arthroplasty in advanced Kienböck's disease is associated with widespread changes in the bones and joints within the wrist [17].
• Based on retrospective data from uncontrolled studies, no active treatment is superior in the treatment of Kienböck's disease [40].
• There are insufficient data to determine whether the outcomes of any intervention for Kienböck's disease are superior to placebo or the natural history of the disease [40].

Key Evidence¶

• [L5] [1] (10.5435/jaaos-d-20-00020)
• [L4] Nonetheless, functional outcomes in medium-term follow-up are discouraging after scaphocapitate arthrodesis for advanced stages of Kienböck disease. [2] (10.1016/j.jhsa.2013.08.063)
• [L4] The current results indicate that radial osteotomies are effective in improving not only short-term clinical outcomes, but also radiographic findings in teenage patients with Kienböck disease. [3] (10.1097/01.blo.0000173254.46899.72)
• [L5] The natural history of Kienbock's disease is not fully known, though it is generally considered a progressive condition that can end in Stage IV changes; treatment strategies focus on biomechanical unloading, vascularized bone grafts, or salvage procedures depending on the stage. [4] (10.1016/j.hcl.2006.07.003)
• [L4] Kienböck's disease progresses substantially faster than previously described and, contrary to current classifications, the articular cartilage of the lunate degenerates in early stages. [5] (10.1016/j.jhsa.2014.06.032)
• [L4] Good and excellent clinical and radiological outcomes can be achieved with both nonsurgical and surgical treatments in skeletally immature patients with Kienböck disease. [6] (10.1016/j.jhsa.2018.02.029)
• [L3] A prospective investigation is needed to delineate the appropriate management and expected outcomes of pediatric and adolescent Kienbock disease. [7] (10.1016/j.jhsg.2026.101068)
• [L4] The long-term clinical benefits of scaphocapitate arthrodesis for treatment of collapsed Kienböck disease are demonstrated. [8] (10.1177/1753193413496177)
• [L4] Radial shortening osteotomy for symptomatic Kienböck's disease yields reasonable long-term function, though approximately one in eight patients underwent salvage surgery. [9] (10.1055/s-0040-1714750)
• [L3] Lunate morphology may affect the severity of Kienböck disease at the time of initial presentation. [10] (10.1016/j.jhsa.2014.12.024)
• [L4] Radial shortening osteotomy should not be contraindicated in advanced Kienbock's disease (without radiocarpal osteoarthritis) as it achieves long-lasting good clinical results with very few complications. [11] (10.1055/s-0039-1688947)
• [L4] Children, adolescents, and elderly patients with Kienböck disease respond well to nonoperative treatments, and this should be considered before any surgical intervention. [12] (10.2106/jbjs.24.01090)
• [L4] We therefore recommend this procedure for the surgical treatment of adolescent Kienböck's disease. [13] (10.1016/j.jhsa.2008.09.019)
• [L5] [14] (10.5435/00124635-200103000-00006)
• [L3] Vascularized bone grafting for stage III Kienböck disease demonstrated favorable long-term results and is recommended as a surgical treatment. [15] (10.1016/j.jhsa.2013.02.010)
• [L3] Traditional radiographic indices measured on plain radiographs have poor diagnostic performance in the detection of carpal collapse in Kienböck's disease. [16] (10.1177/17531934231153966)
• [L4] Tendon ball arthroplasty in advanced Kienböck's disease results in long-term satisfactory clinical outcomes, despite widespread changes in the bones and joints within the wrist. [17] (10.1177/1753193412471183)
• [L4] Radial shortening osteotomy provides decade-long improvement in 75% of patients and seems to be a reasonable treatment for symptomatic Kienböck’s disease. [19] (10.1177/1753193413512222)
• [L5] [20] (10.1177/17531934221146851)
• [L4] [21] (10.1016/j.jhsa.2016.02.016)
• [L4] Free vascularized iliac bone grafting for Kienböck's disease is a reasonable treatment option, and clinical and radiological improvements last for a long period of time. [22] (10.1016/j.jhsa.2007.11.005)
• [L5] The authors propose a unified classification and treatment algorithm that coordinates osseous, vascular, and articular data alongside patient age to allow for more precise and individualized treatment plans for Kienböck disease. [24] (10.1016/j.jhsa.2022.03.014)
• [L4] Scaphocapitate arthrodesis is an effective procedure for treatment of Kienböck disease associated with satisfactory functional outcomes and significant improvement in pain scores and grip strength. [25] (10.1016/j.jhsg.2023.03.014)
• [L4] Radial shortening osteotomy offers at least comparable outcomes with PRC in treating Kienböck's disease, particularly in preserving joint function and patient satisfaction. [26] (10.1016/j.jhsa.2026.02.031)
• [L4] Surgical management of Kienböck ' s disease in adolescent patients can yield satisfactory outcomes in those that fail conservative management. [28] (10.1055/s-0040-1701511)
• [L4] Surgeons should be aware that the diagnosis of Kienböck disease in the precollapse stages is not well defined, as evidenced by the substantial interobserver variability. [29] (10.1177/1558944716677538)
• [L4] The longer-term results of TLA for stage III Kienböck disease are promising. [31] (10.1016/j.jhsa.2018.02.009)
• [L3] The medium- and long-term results of radial shortening osteotomy for Kienböck's disease in patients with negative ulnar variance are comparable to short-term results, providing long-lasting pain relief. [35] (10.1097/blo.0b013e318041d309)
• [L4] [36] (10.1016/j.otsr.2021.103161)
• [L4] [37] (10.1177/1753193416676723)
• [L3] [39] (10.1177/17531934241286115)
• [L4] Based on retrospective data from uncontrolled studies, no active treatment is superior in the treatment of Kienböck's disease and there are insufficient data to determine whether the outcomes of any intervention are superior to placebo or the natural history of the disease. [40] (10.1016/j.jhsa.2010.02.002)
• [L5] [41] (10.1016/j.jhsa.2012.06.029)
• [L4] [42] (10.1177/1753193408098481)
• [L4] The Lichtman et al. classification for Kienböck's disease has good reliability and reproducibility. [43] (10.1177/1753193410373862)
• [L2] Capitate shortening is a safe and effective approach for treatment of the early stages of Kienböck's disease and can be associated with a satisfying outcome. [45] (10.1177/15589447221081564)
• [L5] The manuscript reviews recent advances in diagnostics, classification, and treatment options for Kienböck disease to present a new treatment algorithm that integrates traditional osseous classification with perfusion/viability and articular cartilage-based classifications. [46] (10.1016/j.jhsa.2016.02.013)
• [L3] Dorsal wrist swelling in Kienböck ' s disease is a common manifestation and constitutes a part of pathology of Kienböck ' s disease, although further study is required to clarify the relation between wrist swelling and etiology of Kienböck ' s disease. [53] (10.1055/s-0038-1661420)
• [L5] There is limited, low-quality evidence that surgical treatment slows progression of Kienböck's disease, and many uncontrolled case series document slight improvement in motion and grip after surgical treatment without clear evidence that this is better than placebo or no intervention. [56] (10.1016/j.jhsa.2009.10.013)
• [L4] Arthroscopic lunate core decompression appears to be an effective and safe surgery for treating Kienböck disease on the basis of mid-term follow-up. [59] (10.1016/j.jhsa.2023.02.011)
• [L4] Computed tomography of the lunate in Kienböck disease is an important investigative tool. [66] (10.1016/j.jhsa.2018.05.008)
• [L4] This study confirms that the Bain and Begg arthroscopic classification and an articular-based approach to Kienböck disease provide a high probability of good longterm relief of pain and a minimal chance of requiring a salvage procedure. [67] (10.1016/j.jhsa.2020.11.004)
• [L4] Proton density–weighted MRIs but not fast-field echo images using a 47-mm microscopy coil reflected the extent and localization of the necrotic area in Kienböck-diseased lunates, as evidenced by comparison with histological analyses of the lunate specimens. [70] (10.1016/j.jhsa.2011.09.027)
• [L4] The treatment of Kienböck disease with vascularized bone graft from the dorsum of the radius has encouraging results and needs no other additional procedures. [73] (10.1007/s00402-008-0586-x)
• [L4] Given the significant postoperative reduction in associated pain symptoms at the time of follow-up, scaphocapitate arthrodesis should be considered as a treatment option for wrist salvage in the patient with advanced Kienbock's disease. [79] (10.1007/s11552-014-9705-z)

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