Patients › General-Health
Exames dos nervos e estudos de condução nervosa
What nerve conduction studies and EMG are, why they are done for carpal tunnel and other nerve problems, what to expect, and how accurate they are.
O que é¶
Os exames dos nervos medem o quanto os seus nervos conduzem bem os sinais elétricos. Existem dois métodos elétricos para avaliar a função dos nervos, e ambos se mostraram úteis na prática [1]. O exame principal se chama estudo de condução nervosa. Um pequeno aparelho envia um pulso minúsculo ao nervo e registra a velocidade com que o sinal percorre o nervo. Se um nervo estiver comprimido ou lesionado, o sinal fica mais lento ou mais fraco.
Esses exames são usados com mais frequência na síndrome do túnel do carpo, em que o nervo na parte da frente do punho está sob pressão. Eles são considerados uma parte indispensável da avaliação antes da cirurgia para essa condição [2]. A maioria dos médicos não opera sem essa confirmação [3]. Os exames também podem ajudar em outros problemas dos nervos, como a pressão sobre o nervo no cotovelo (síndrome do túnel cubital) [4].
Geralmente, você fará um segundo exame na mesma consulta. Nele, uma agulha fina é colocada em alguns músculos. Ele verifica o quanto os músculos respondem bem ao estímulo dos seus nervos. Juntos, esses exames são chamados de estudos eletrodiagnósticos, o que significa simplesmente exames que usam eletricidade para estudar os nervos e os músculos.
Os exames funcionam porque os nervos conduzem sinais da mesma forma que os fios conduzem corrente. Um nervo comprimido se comporta como um cabo apertado, de modo que o sinal ao longo dele fica atrasado ou reduzido. Os resultados dão uma medida do grau de comprometimento do nervo, e esse é o melhor indicador disponível da gravidade geral da doença [5]. O valor desses exames está em acertar o diagnóstico e avaliar a sua gravidade, e não em prever como você vai se sentir depois da cirurgia [6].
Vale a pena saber de uma coisa: um exame normal não descarta a síndrome do túnel do carpo, porque a compressão do nervo pode ir e vir.
Funciona mesmo?¶
A resposta honesta é que esses exames são bons para algumas finalidades e limitados para outras. Eles são um complemento útil na investigação da síndrome do túnel do carpo, especialmente quando os exames padrão dão resultado normal [7]. Um estudo de um exame especial dos nervos verificou que ele detectou a condição em 69% dos casos, e todos os resultados positivos estavam corretos. Quando esse exame foi combinado com outra forma de medir a sensibilidade, ele detectou 84% dos casos [8].
Os exames também ajudam a confirmar o diagnóstico antes da cirurgia. Quando os seus sinais e sintomas indicam uma pressão leve a moderada sobre o nervo e a cirurgia está sendo considerada, exames adicionais podem aumentar a chance de a cirurgia ser direcionada a um problema real e tratável [9]. Um estudo encontrou uma grande diferença entre o número de pessoas diagnosticadas apenas pelos sintomas (73%) e o número confirmado por esses exames e pelo ultrassom (51%) [10]. Essa diferença é justamente o motivo pelo qual os exames são importantes: eles identificam quem realmente tem um problema no nervo que a cirurgia pode ajudar.
Há limitações. A qualidade desses exames varia entre os profissionais, e alguns laudos trazem mais detalhes do que outros [11]. Os critérios para interpretá-los também precisam ser definidos com mais precisão, para que os diagnósticos sejam corretos e a cirurgia não seja feita quando não é necessária [12]. E os exames não conseguem mostrar tudo. Eles medem o nervo, não os seus sintomas.
Alguns achados são contraditórios. As alterações nos resultados dos exames após uma injeção de corticoide não foram significativas em dois anos [13]. Por outro lado, uma boa resposta a uma injeção é um sinal útil de como a cirurgia pode correr [14]. Uma medida dos exames, chamada latência motora distal, que é simplesmente o tempo que o sinal leva para chegar a um músculo, tem algum valor para prever como você vai evoluir depois da cirurgia [15].
Portanto, os exames funcionam bem como ferramenta de diagnóstico. São menos confiáveis como bola de cristal para a sua recuperação.
Quais são os riscos?¶
Os exames dos nervos são seguros, mas você deve saber o que esperar. O efeito mais comum é o desconforto durante o próprio exame. Os pulsos elétricos dão a sensação de pequenas batidinhas ou fisgadas. Se uma agulha fina for colocada em um músculo, você vai sentir uma picada rápida, e o músculo pode ficar dolorido por um ou dois dias depois. A versão do exame feita no dedo anelar é rápida e exige muito pouco esforço de você [16].
Os pulsos elétricos não deixam efeitos duradouros na pele nem nos tecidos. Os pulsos são pequenos e passam pela pele sem danificá-la. Se você fizer o exame com agulha, os locais da agulha podem ficar levemente sensíveis, e pode aparecer um pequeno hematoma. Isso melhora sozinho.
As evidências não descrevem efeitos no restante do corpo, e não descrevem complicações raras, mas graves, causadas por esses exames. Vale a pena dizer isso com clareza: os estudos em que esta página se baseia avaliam o quanto os exames diagnosticam e preveem bem, e não os danos, por isso as informações aqui sobre riscos graves são limitadas.
Um dos riscos não é físico. Os exames podem ser interpretados de forma diferente por profissionais diferentes, e alguns laudos trazem mais detalhes do que outros [11]. Um laudo que lista pequenas alterações sem explicá-las pode levar a uma conclusão errada [17]. Os critérios para interpretar os exames também precisam ser definidos com mais precisão, para que os diagnósticos sejam corretos e a cirurgia não seja feita quando não é necessária [12]. Essa é a principal coisa que pode dar errado: não o exame em si, mas um diagnóstico baseado em um laudo incompleto ou pouco claro.
Se você já recebeu uma injeção de corticoide para a síndrome do túnel do carpo, as alterações nos resultados dos exames após essa injeção não foram significativas em dois anos [13]. Isso significa que a injeção não parece mudar o que os exames mostram a longo prazo, de modo que repetir o exame após uma injeção ainda deve dar uma ideia justa do estado do seu nervo.
Peça ao seu médico ou à pessoa que faz o exame para explicar o laudo a você. Uma descrição clara do que o exame encontrou, e do que isso significa, faz parte de um bom resultado.
É a opção certa para você?¶
Se os seus sintomas indicam síndrome do túnel do carpo e a cirurgia é uma possibilidade, esses exames geralmente fazem parte do plano. A maioria dos médicos não opera sem essa confirmação [3]. Exames adicionais podem aumentar a chance de a cirurgia ser direcionada a um problema real e tratável no nervo [9]. Isso é importante, porque os exames acertam o diagnóstico e mostram a gravidade da pressão sobre o seu nervo [6].
Eles podem ser menos úteis se os seus sintomas forem vagos ou forem e voltarem. A compressão do nervo pode passar despercebida no dia do exame. Um resultado normal não descarta a síndrome do túnel do carpo. Os exames também não conseguem prever como você vai se sentir depois da cirurgia, por isso são uma ferramenta de diagnóstico, e não uma promessa sobre a sua recuperação [6].
A principal alternativa é o ultrassom, que também pode verificar se há pressão sobre o nervo [9]. O seu médico pode sugerir um deles ou ambos. Cada um tem os seus pontos fortes, e a escolha certa depende dos seus sintomas e do exame físico.
Esta deve ser uma decisão compartilhada com o seu médico. Pergunte o que se espera que o exame mostre e o que vai acontecer se o resultado for normal. Se tiver dúvidas sobre os riscos do próprio exame, leia a seção acima sobre os riscos.
Conclusão¶
Se a cirurgia para a síndrome do túnel do carpo está sendo considerada, vale a pena fazer esses exames. Eles confirmam se a pressão sobre o seu nervo é real e mostram a sua gravidade [6]. Exames adicionais podem aumentar a chance de a cirurgia ser direcionada a um problema real e tratável [9]. Tenha uma expectativa realista: os exames são bons para o diagnóstico, mas não conseguem prever como você vai se sentir depois da cirurgia [6]. A ressalva mais importante é que um resultado normal não descarta a síndrome do túnel do carpo, porque a compressão do nervo pode ir e vir. Peça uma explicação clara do seu laudo antes de tomar qualquer decisão.
Referências¶
[1] Sensory threshold and conductance testing in nerve injuries. The Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand. 1986. DOI: 10.1016/0266-7681(86)90252-4
[2] Correlation of Clinical Signs with Nerve Conduction Tests in the Diagnosis of Carpal Tunnel Syndrome. Journal of Hand Surgery. 1994. DOI: 10.1016/0266-7681(94)90244-5
[3] Current Practice in the Use of Nerve Conduction Studies in Carpal Tunnel Syndrome by Surgeons in the Netherlands. Journal of Hand Surgery (European Volume). 2007. DOI: 10.1016/j.jhse.2007.09.007
[4] Diagnosis of Ulnar Neuropathy at the Elbow Using Ultrasound — A Comparison to Electrophysiologic Studies. The Journal of Hand Surgery. 2023. DOI: 10.1016/j.jhsa.2023.08.014
[5] Use of nerve conduction studies in carpal tunnel syndrome. Journal of Hand Surgery (European Volume). 2023. DOI: 10.1177/17531934231191685
[6] Electrical studies as a prognostic factor in the surgical treatment of carpal tunnel syndrome. The Journal of Hand Surgery. 1996. DOI: 10.1016/s0363-5023(96)80384-4
[7] Provocative motor nerve conduction testing in presumptive carpal tunnel syndrome unconfirmed by traditional electrodiagnostic testing. The Journal of Hand Surgery. 1997. DOI: 10.1016/s0363-5023(97)80045-7
[8] The utility of portable nerve conduction testing for patients with carpal tunnel syndrome: A prospective clinical study. The Journal of Hand Surgery. 1992. DOI: 10.1016/0363-5023(92)90117-8
[9] Diagnosis of Mild-to-moderate Idiopathic Median Neuropathy at the Carpal Tunnel Based on Signs and Symptoms is Discordant From Diagnosis Based on Electrodiagnostic Studies and Ultrasound. Clinical Orthopaedics & Related Research. 2023. DOI: 10.1097/corr.0000000000002751
[10] CORR Insights®: Diagnosis of Mild-to-moderate Idiopathic Median Neuropathy at the Carpal Tunnel Based on Signs and Symptoms is Discordant From Diagnosis Based on Electrodiagnostic Studies and Ultrasound. Clinical Orthopaedics & Related Research. 2023. DOI: 10.1097/corr.0000000000002822
[11] Electrodiagnostic reports of median neuropathy at the wrist. The Journal of Hand Surgery. 1998. DOI: 10.1016/s0363-5023(98)80089-0
[12] Electrodiagnostic testing and carpal tunnel release outcome. The Journal of Hand Surgery. 1997. DOI: 10.1016/s0363-5023(05)80209-6
[13] Nerve Conduction Studies after Treatment for Carpal Tunnel Syndrome. Journal of Hand Surgery. 1992. DOI: 10.1016/0266-7681(92)90191-4
[14] Diagnostic and therapeutic value of carpal tunnel injection. The Journal of Hand Surgery. 1984. DOI: 10.1016/s0363-5023(84)80065-9
[15] Carpal Tunnel Syndrome: Neurophysiological Results of Surgery Based on Preoperative Electrodiagnostic Testing. Journal of Hand Surgery. 1997. DOI: 10.1016/s0266-7681(97)80355-5
[16] Relative slowing of the median antidromic sensory nerve conduction velocity to the ring finger in screening for carpal tunnel syndrome. The Journal of Hand Surgery. 2004. DOI: 10.1016/j.jhsa.2004.04.026
[17] Electrodiagnostic testing in hand surgery. The Journal of Hand Surgery. 1996. DOI: 10.1016/s0363-5023(96)80298-x
Evidence & references
This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.
Overview¶
- Nerve conduction studies serve as a measure of impaired nerve function and are the best available indicator of overall disease severity with some prognostic value for surgical outcome [1].
- Nerve conduction studies are considered an indispensable part of the pre-operative evaluation for carpal tunnel syndrome [2].
- Provocative nerve conduction testing is a useful and simple addition to the overall evaluation of patients with carpal tunnel syndrome, particularly those with otherwise normal findings on traditional electrodiagnostic studies [3].
- The selection of an appropriate electrical screening test for peripheral nerve injury depends on the prevalence and seriousness of the target disease and the relative consequences of over- and underdiagnosis [4].
- The absence of any real difference in nerve conduction time between a working group with symptoms and a group with diagnosed carpal tunnel syndrome indicates a high probability that many participants with symptoms would have had abnormal findings on standard electrodiagnostic tests [5].
- The value of preoperative nerve conduction studies lies in obtaining the correct diagnosis and determining the severity of the median nerve disease, not in predicting postoperative outcome [6].
- Electrodiagnostic criteria used in some referenced studies were inadequate and not the most sensitive available, potentially leading to the erroneous conclusion that electrodiagnostic studies offer no additional diagnostic power in carpal tunnel syndrome [7].
- The value of electrodiagnostic testing is not negated by findings that it does not predict postoperative outcome [8].
- When signs and symptoms suggest mild-to-moderate median neuropathy and surgery is being considered, patients and clinicians might consider additional testing, such as electrodiagnostic studies or ultrasound, to increase the probability of actual median neuropathy that can benefit from surgery [9].
- Clinical, electrodiagnostic, and physical examination criteria need better definition to avoid inaccurate diagnoses and unnecessary surgeries [10].
- Highly sensitive tests are required to assess or exclude the diagnosis in one quarter of cases of carpal tunnel syndrome [11].
- Nerve conduction studies were more sensitive than sensibility testing in confirming the diagnosis of carpal tunnel syndrome [13].
- The combination of nerve conduction studies and sensibility testing is more sensitive than either test alone in confirming the diagnosis of carpal tunnel syndrome [13].
- Given specific clinical criteria for establishing the diagnosis of carpal tunnel syndrome, electrodiagnostic testing does not appear to correlate with improved final symptomatic outcome after carpal tunnel release [20].
- Surgical intervention is advocated for patients with symptoms only, even when electrodiagnostic studies are normal, in the context of cubital tunnel syndrome [21].
- The majority of neurosurgeons and orthopaedic surgeons seldom operate without electrodiagnostic confirmation in line with the Dutch consensus guideline on this subject [29].
- When used together, Semmes-Weinstein monofilament mappings and sensory nerve conduction parameters present a clearer picture of the patient's sensory status than either test used alone [31].
- Receiver operating characteristic curves showed distal sensory latency measurement to be a superior diagnostic test for carpal tunnel syndrome, with 3.3 ms as optimal upper limit of normal, giving a sensitivity of 74% and a specificity of 87% [45].
How It Works¶
Diagnostic Utility and Role¶
- The clinical, electrodiagnostic, and physical examination criteria need better definition to avoid inaccurate diagnoses and unnecessary surgeries [10].
- Electrodiagnostic studies are used as part of a clinical evaluation process and are considered a reasonable way to practice medicine [12].
Sensitivity and Specificity¶
- Nerve conduction studies were more sensitive than sensibility testing in confirming the diagnosis of carpal tunnel syndrome, but the combination of the two studies is more sensitive than either test alone [13].
- The sensitivity of the neurometer test alone was 69% and specificity was 100%, increasing to 84% sensitivity when combined with quantitative sensibility testing [28].
- The relative slowing of the antidromic sensory conduction velocity of the median nerve to the ring finger is determined easily and efficiently and imposes minimal strain on the patient [34].
Prognostic Value and Outcomes¶
- Compound muscle action potential amplitude, but not other conventional electrodiagnostic parameters, was predictive of functional outcomes after in situ decompression of the ulnar nerve [22].
- Suprascapular nerve dysfunction, evidenced by reduced nerve amplitudes and supraspinatus muscle atrophy, significantly predicts poor functional outcomes following shoulder hemiarthroplasty, even when tuberosities are well healed [19].
- This strength recovers gradually as the median nerve heals, but never returns to normal, indicating that this test can be extrapolated to the reinnervation of the abductor pollicies brevis [23].
Technical Considerations and Reporting¶
- There is variability with respect to the thoroughness of electrodiagnostic studies and in the quality of information in the reports [16].
- Electrodiagnostic reports should specifically indicate abnormalities of latency and conduction and present a clear description of the probable pathophysiologic processes rather than just compiling slight abnormalities [26].
- The conduction velocity of the ulnar nerve after an anterior transposition is determined by both the position of the elbow and the location for the measurement of the skin distance [37].
Physiological Mechanisms and Intraoperative Findings¶
- When in situ nerve strain reached 8.1 ± 0.5%, the compound muscle action potential was not evoked [33].
- Intraoperative conduction latencies indicated a dramatic and immediate reduction in the conduction latency across the carpal canal in all but seven patients, two of whom had diabetes [36].
- Electrodiagnostic studies revealed an acute median nerve lesion at the wrist with motor and/or sensory conduction blocks in 20/30 women with pregnancy-related carpal tunnel syndrome [18].
Comparative Modalities¶
- Ultrasound is a valid alternative confirmatory test compared with electrodiagnostic studies in detecting ulnar neuropathy at the elbow [14].
- The study confirms the high diagnostic value of the pre-operative antidromic sensory conduction velocity findings [25].
What the Evidence Shows¶
Diagnostic Role and Sensitivity¶
- The absence of any real difference in nerve conduction time between the working group with symptoms and the group with diagnosed carpal tunnel syndrome indicates a high probability that many participants with symptoms would have had abnormal findings on standard electrodiagnostic tests [5].
- There is a severe discordance between the estimated prevalence of mild-to-moderate carpal tunnel syndrome based on clinical signs and symptoms (73%) versus electrodiagnostic studies and ultrasound (51%) [27].
- The authors argue that the electrodiagnostic criteria used in the referenced study were inadequate and not the most sensitive available, potentially leading to the erroneous conclusion that electrodiagnostic studies offer no additional diagnostic power in carpal tunnel syndrome [7].
- Carpal tunnel injection is a reasonably accurate diagnostic test, as a good response to injection is an excellent diagnostic and prognostic sign for surgical treatment [42].
Prognostic Value and Outcomes¶
- Upper arm motor nerve conduction velocity might be a useful predictor of poor surgical outcome in cubital tunnel syndrome [32].
- Distal motor latency is a simple test with a predictive value of the postoperative neurophysiological and clinical outcome of carpal tunnel syndrome [39].
- The changes in electrophysiological findings occurring spontaneously in carpal tunnel syndrome and after treatment by injection are not statistically significant at two years [38].
Clinical Application and Reporting¶
- The author continues to use electrodiagnostic studies as part of a clinical evaluation process and considers this a reasonable way to practice medicine [12].
- The author proposes that the clinical, electrodiagnostic, and physical examination criteria need better definition to avoid inaccurate diagnoses and unnecessary surgeries [10].
- The study confirms the high diagnostic value of the pre-operative antidromic sensory conduction velocity findings in carpal tunnel syndrome [25].
- Surgical intervention is advocated for patients with symptoms only, even when electrodiagnostic studies are normal, in cases of cubital tunnel syndrome [21].
- The incidence of abnormal conduction times was not reliably correlated with either age or duration of paralysis in the paraplegic hand [24].
- In primates, there is no significant difference in the conduction velocity of peripheral nerves repaired in adults and those repaired in early life [15].
- Although there are essential differences between Semmes-Weinstein monofilament mappings and sensory nerve conduction parameters, when used together they present a clearer picture of the patient's sensory status than either test used alone [31].
- The strength of the abductor pollicis brevis recovers gradually as the median nerve heals but never returns to normal, indicating that this test can be extrapolated to the reinnervation of the abductor pollicis brevis [23].
- Chitosan phonophoresis demonstrated significant improvements in nerve conduction, pain reduction, and enhancement of hand function for mild to moderate cubital tunnel syndrome [17].
- All patients had good clinical and electrophysiological recovery at 6 months following single-stage opponensplasty added at the time of release for severe carpal tunnel syndrome [41].
- Three weeks after the operation, 77% of the patients in the tourniquet group had denervation in other than thenar muscles [46].
Practical Considerations¶
Diagnostic Interpretation and Utility¶
- Nerve conduction studies serve as a measure of impaired nerve function and the best available indicator of overall disease severity, rather than a test that determines the diagnosis [1].
- The value of preoperative nerve conduction studies lies in obtaining the correct diagnosis and determining the severity of median nerve disease, not in predicting postoperative outcome [6].
- Electrodiagnostic testing does not appear to correlate with improved final symptomatic outcome after carpal tunnel release given specific clinical criteria for establishing the diagnosis [20].
- When signs and symptoms suggest mild-to-moderate median neuropathy and surgery is being considered, patients and clinicians might consider additional testing, such as EDS or US, to increase the probability of actual median neuropathy that can benefit from surgery [9].
- The authors argue that the electrodiagnostic criteria used in the referenced study were inadequate and not the most sensitive available, potentially leading to the erroneous conclusion that electrodiagnostic studies offer no additional diagnostic power in CTS [7].
- This does not negate the value of electrodiagnostic testing [8].
Testing Variations and Screening¶
- Provocative nerve conduction testing is a useful and simple addition to the overall evaluation of patients with CTS, particularly those with otherwise normal findings on traditional electrodiagnostic studies [3].
- The absence of any real difference in nerve conduction time between the working group with symptoms and the group with diagnosed CTS indicates a high probability that many of the participants with symptoms would have had abnormal findings on standard electrodiagnostic tests [5].
- There is a significant discrepancy between the practice recommended by the Danish Society of Neurophysiology of performing neurophysiological investigations in all cases of suspected CTS and what is actually done in most surgical departments [35].
Specific Clinical Scenarios¶
- Upper arm motor nerve conduction velocity (MNCV) might be a useful predictor of poor surgical outcome in cubital tunnel syndrome [32].
- Surgical intervention is advocated for patients with symptoms only, even when electrodiagnostic studies are normal, in cases of electrodiagnostic-negative cubital tunnel syndrome [21].
- SSN dysfunction, evidenced by reduced nerve amplitudes and supraspinatus muscle atrophy, significantly predicts poor functional outcomes following shoulder hemiarthroplasty, even when tuberosities are well healed [19].
- The incidence of abnormal conduction times in the paraplegic hand was not reliably correlated with either age or duration of paralysis [24].
- Intraoperative electrodiagnosis may offer limited value in neonatal brachial plexus palsy surgery, but there is insufficient evidence to reach robust conclusions [44].
- This underscores the need for surgeons to carefully evaluate suprascapular nerve integrity in cases of rotator cuff tear [40].
Methodological and Prognostic Notes¶
- Only studies with randomization, blinding, and sham injection or sham surgery can address subjective symptoms and satisfaction reliably and accurately [30].
Key Evidence¶
- [L5] Nerve conduction studies should be understood not as a test that determines the diagnosis but as a measure of impaired nerve function, serving as the best available indicator of overall disease severity with some prognostic value for surgical outcome. [1] (10.1177/17531934231191685)
- [L3] We consider nerve conduction studies to be an indispensable part of the pre-operative evaluation. [2] (10.1016/0266-7681(94)90244-5)
- [L2] Provocative nerve conduction testing is a useful and simple addition to the overall evaluation of patients with CTS, particularly those with otherwise normal findings on traditional electrodiagnostic studies. [3] (10.1016/s0363-5023(97)80045-7)
- [L3] The selection of an appropriate electrical screening test for peripheral nerve injury, such as entrapment neuropathy, depends on the prevalence and seriousness of the target disease and the relative consequences of over- and underdiagnosis. [4] (10.1016/s0363-5023(96)80165-1)
- [L3] The absence of any real difference in nerve conduction time between the working group with symptoms and the group with diagnosed CTS indicates a high probability that many of the participants with symptoms would have had abnormal findings on standard electrodiagnostic tests. [5] (10.1016/0363-5023(92)90116-7)
- [L5] The value of preoperative nerve conduction studies lies in obtaining the correct diagnosis and determining the severity of the median nerve disease, not in predicting postoperative outcome. [6] (10.1016/s0363-5023(96)80384-4)
- [L5] The authors argue that the electrodiagnostic criteria used in the referenced study were inadequate and not the most sensitive available, potentially leading to the erroneous conclusion that electrodiagnostic studies offer no additional diagnostic power in CTS. [7] (10.1067/jhsu.2000.jjhsu00025a1le01)
- [L5] This does not negate the value of electrodiagnostic testing. [8] (10.1016/s0363-5023(96)80222-x)
- [L3] When signs and symptoms suggest mild-to-moderate median neuropathy and surgery is being considered, patients and clinicians might consider additional testing, such as EDS or US, to increase the probability of actual median neuropathy that can benefit from surgery. [9] (10.1097/corr.0000000000002751)
- [L5] The author proposes that the clinical, electrodiagnostic, and physical examination criteria need better definition to avoid inaccurate diagnoses and unnecessary surgeries. [10] (10.1016/s0363-5023(05)80209-6)
- [L3] Highly sensitive tests are required to assess or exclude the diagnosis in one quarter of cases of carpal tunnel syndrome. [11] (10.1016/0266-7681(94)90245-3)
- [L5] The author continues to use electrodiagnostic studies as part of a clinical evaluation process and considers this a reasonable way to practice medicine. [12] (10.1016/s0363-5023(96)80380-7)
- [L4] The results indicate that nerve conduction studies were more sensitive than sensibility testing in confirming the diagnosis of carpal tunnel syndrome, but the combination of the two studies is more sensitive than either test alone. [13] (10.1016/s0363-5023(82)80176-7)
- [L4] Ultrasound is a valid alternative confirmatory test compared with electrodiagnostic studies in detecting ulnar neuropathy at the elbow. [14] (10.1016/j.jhsa.2023.08.014)
- [L3] The study demonstrates that in primates there is no significant difference in the conduction velocity of peripheral nerves repaired in adults and those repaired in early life. [15] (10.1016/s0363-5023(83)80199-3)
- [L4] There is variability with respect to the thoroughness of electrodiagnostic studies and in the quality of information in the reports. [16] (10.1016/s0363-5023(98)80089-0)
- [L1] This approach demonstrated significant improvements in nerve conduction, pain reduction, and enhancement of hand function. [17] (10.1016/j.jht.2024.02.006)
- [L4] Electrodiagnostic studies revealed an acute median nerve lesion at the wrist with motor and/or sensory conduction blocks in 20/30 women. [18] (10.1016/s0266-7681(98)80232-5)
- [L3] SSN dysfunction, evidenced by reduced nerve amplitudes and supraspinatus muscle atrophy, significantly predicts poor functional outcomes following SHA, even when tuberosities are well healed. [19] (10.1016/j.jse.2025.07.001)
- [L3] Given specific clinical criteria for establishing the diagnosis of carpal tunnel syndrome, electrodiagnostic testing does not appear to correlate with improved final symptomatic outcome after carpal tunnel release. [20] (10.1016/s0363-5023(96)80164-x)
- [L2] We advocate surgical intervention for patients with symptoms only, even when electrodiagnostic studies are normal. [21] (10.1053/jhsu.2001.26327)
- [L2] Compound muscle action potential amplitude, but not other conventional electrodiagnostic parameters, was predictive of functional outcomes after in situ decompression of the ulnar nerve. [22] (10.1016/j.jhsa.2022.10.008)
- [L5] This strength recovers gradually as the median nerve heals, but never returns to normal, indicating that this test can be extrapolated to the reinnervation of the abductor pollicies brevis. [23] (10.1016/s0266-7681(03)00022-6)
- [L4] The incidence of abnormal conduction times was not reliably correlated with either age or duration of paralysis. [24] (10.1016/s0363-5023(88)80132-1)
- [L4] The study confirms the high diagnostic value of the pre-operative antidromic sensory conduction velocity findings. [25] (10.1016/0266-7681(88)90161-1)
- [L5] EDX reports should specifically indicate abnormalities of latency and conduction and present a clear description of the probable pathophysiologic processes rather than just compiling slight abnormalities. [26] (10.1016/s0363-5023(96)80298-x)
- [L5] There is a severe discordance between the estimated prevalence of mild-to-moderate carpal tunnel syndrome based on clinical signs and symptoms (73%) versus electrodiagnostic studies and ultrasound (51%), calling into question whether clinicians can confidently diagnose patients with mild-to-moderate CTS. [27] (10.1097/corr.0000000000002822)
- [L3] The sensitivity of the neurometer test alone was 69% and specificity was 100%, increasing to 84% sensitivity when combined with quantitative sensibility testing. [28] (10.1016/0363-5023(92)90117-8)
- [L4] The majority of neurosurgeons and orthopaedic surgeons seldom operate without electrodiagnostic confirmation in line with the Dutch consensus guideline on this subject. [29] (10.1016/j.jhse.2007.09.007)
- [L4] Although there are essential differences in these two tests, when used together they present a clearer picture of the patient's sensory status than either test used alone. [31] (10.1016/s0894-1130(87)80010-8)
- [L3] Upper arm motor nerve conduction velocity (MNCV) might be a useful predictor of poor surgical outcome. [32] (10.1177/17585732241293360)
- [Paper] The results showed that when the in situ nerve strain reached 8.1 ± 0.5%, the compound muscle action potential was not evoked. [33] (10.1016/s0736-0266(02)00080-3)
- [L3] The relative slowing of the antidromic sensory conduction velocity of the median nerve to the ring finger is determined easily and efficiently and imposes minimal strain on the patient. [34] (10.1016/j.jhsa.2004.04.026)
- [L4] There is a significant discrepancy between the practice recommended by the Danish Society of Neurophysiology of performing neurophysiological investigations (NI) in all cases of suspected CTS and what is actually done in most surgical departments. [35] (10.1016/s0266-7681(97)80443-3)
- [L4] The results of intraoperative conduction latencies indicated a dramatic and immediate reduction in the conduction latency across the carpal canal in all but seven patients, two of whom had diabetes. [36] (10.1016/s0363-5023(78)80119-1)
- [L4] The conduction velocity of the ulnar nerve after an anterior transposition is determined by both the position of the elbow and the location for the measurement of the skin distance. [37] (10.1016/s0363-5023(87)80051-5)
- [L3] The changes in electrophysiological findings occurring spontaneously in carpal tunnel syndrome and after treatment by injection are not statistically significant at two years. [38] (10.1016/0266-7681(92)90191-4)
- [L3] DML is a simple test with a predictive value of the postoperative neurophysiological and clinical outcome of carpal tunnel syndrome. [39] (10.1016/s0266-7681(97)80355-5)
- [L5] This underscores the need for surgeons to carefully evaluate suprascapular nerve integrity in such cases. [40] (10.1186/s12891-025-09195-6)
- [L3] All patients had good clinical and electrophysiological recovery at 6 months. [41] (10.1177/1558944716660555fx)
- [L4] Results suggest that carpal tunnel injection is also a reasonably accurate diagnostic test, as a good response to injection is an excellent diagnostic and prognostic sign for surgical treatment. [42] (10.1016/s0363-5023(84)80065-9)
- [L4] Intraoperative electrodiagnosis may offer limited value in neonatal brachial plexus palsy surgery, but there is insufficient evidence to reach robust conclusions. [44] (10.1177/17531934261478357)
- [L3] Receiver operating characteristic curves showed distal sensory latency measurement to be a superior diagnostic test, with 3.3 ms as optimal upper limit of normal, giving a sensitivity of 74% and a specificity of 87%. [45] (10.1016/s0363-5023(96)80020-7)
- [L1] Three weeks after the operation 77% of the patients in the tourniquet group had denervation in other than thenar muscles. [46] (10.1016/s0363-5023(89)80011-5)
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