Patients › Shoulder
肩袖关节病
Rotator cuff arthropathy: shoulder arthritis following a long-standing, massive rotator cuff tear and its impact on function.
您正在感受到的症状¶
肩袖关节病是在长期存在的肩袖撕裂之后发生的肩关节炎。肩袖是一组肌腱,在您抬起手臂时使肩关节的球体保持居中。当这些肌腱不复存在时,关节会以一种原本并非为之设计的方式磨损,而这种磨损正是您所感受到的。
疼痛通常位于肩关节本身的深处,即球体与关节窝相接的部位。疼痛往往也会出现在上臂外侧。将手臂举过头顶、伸手够架子,或用患侧提购物袋,都会使疼痛加重。许多人发现疼痛在夜间加剧,侧卧压到患侧肩部可能会使您痛醒。起床活动后疼痛通常会稍有缓解,但在忙碌的一天之后又会再次加重。
由于肩袖已无法发挥作用,手臂的活动方式也会随之改变。您可能会注意到的不只是疼痛,还有无力:即使借助摆动将手臂甩起,也很难把手臂抬到肩膀高度或更高。把手伸到身后戴项链、晾晒衣物或从头上套毛衣,都可能感到别扭或无法完成。有些人会在肩部顶端附近出现一个光滑的圆形隆起,这是球体向上移位所致。
在数周和数月间,这些问题通常是逐渐加重的,而不是一下子全部出现。伸手拉安全带、用水壶倒水或穿外套等简单的事情,可能会成为一天中最困难的部分。
有些信号需要紧急处理。如果您的肩部变得发热、发红、肿胀并疼痛,尤其是伴有发烧时,请当天前往急诊科。如果您的手臂变得苍白、冰冷、发白或发蓝,或者突然失去感觉或无法活动,也请当天前往急诊科。如果您的症状没有缓解、在数周内逐渐加重,或在夜间将您痛醒,请咨询您的全科医生或要求我们进行专科评估。
实际发生了什么¶
健康的肩关节就像一个球体靠在一个浅窝中。肩袖肌腱包绕着球体,在您抬臂时使其保持居中。可以把它们想象成固定帐篷支杆的拉绳。拉绳一旦没有了,支杆就会倾斜。
在您的肩部,位于肩部外侧的强壮三角肌在您抬起手臂时仍会发力牵拉。由于没有肩袖将球体向下压住并保持居中,这种牵拉会把球体向上拉。随后,球体会与其上方的骨头——肩峰,即肩部顶端的骨性顶棚——相互摩擦。这两个表面本不应相互接触,因此会彼此磨损。这种磨损就是关节炎,这也解释了为什么您的疼痛位于关节深处,以及为什么球体会向上移位,形成您可能摸到的那个圆形隆起。
这种磨损也解释了无力的原因。抬起手臂依赖于球体保持居中,而您的球体已不再居中。因此,您虽然用了力,手臂却无法像应有的那样抬起。
有一种方法可以解决这个问题。反式肩关节置换术将球体和关节窝的位置互换:球体被安装在关节窝一侧,而关节窝被安装在手臂一侧。这一改变降低了关节的中心,使三角肌获得更长的杠杆来发力,有点像在离门铰链更远的地方握住门把手。这样,三角肌就能独立抬起手臂,而不需要已缺失的肩袖肌腱。新关节的设计还使球体无法滑脱,从而在您活动时保持稳定。
由于三角肌接管了这项工作,术后肩部的活动方式会有所不同。您的肩胛骨会比以前承担更多的活动。大多数人会在不知不觉中适应这一点,这也是新关节恢复活动能力的方式之一。
我们可以采取的措施¶
Mater Private Hospital Rockhampton 的上肢外科医生 Kieran Hirpara 医生会从最适合您病情的微创方案入手。患者通常由全科医生(GP)转诊至我们的诊所;如果物理治疗师建议您就诊,您仍需获得全科医生的转诊才能符合 Medicare 报销资格。诊所评估包括了解您的病史、进行体格检查,并在必要时安排影像学检查,以明确诊断。
第一步通常是非手术治疗。改变肩部的使用方式会有所帮助:避免举过头顶够取物品、用另一只手臂提举,以及合理安排事务,避免用患侧提重物。物理治疗旨在保持肩部的活动能力,增强仍能发挥作用的肌肉,并缓解疼痛。我们通常会给予数月的充分尝试,然后再考虑进一步的措施。
止痛药物可以作为辅助。简单的止痛药和抗炎药(即可减轻肿胀和刺激的药物)通常是起始选择。您的全科医生可以指导哪些药物对您来说是安全的。
如果这些措施未能带来足够的改善,可以考虑手术。对于肩袖关节病,手术方式是反式肩关节置换术,它将球体和关节窝的位置互换,使三角肌能够在没有肩袖肌腱的情况下抬起手臂。我们会与您详细讨论手术涉及哪些内容、它能为您做到什么和做不到什么,以及它是否符合您的目标。这个决定由您与我们共同做出,取决于您的疼痛、您的活动能力以及对您日常生活而言重要的事情。
预期情况¶
肩袖关节病通常在数月乃至数年间缓慢进展,而不是突然出现。如果不治疗,疼痛和无力往往会持续妨碍您的生活。关节内的磨损不会自行逆转,因此大多数人会发现,随着时间推移,肩部对他们的限制会越来越多,而不是越来越少。
在恰当的治疗下,前景则有所不同。物理治疗和简单止痛药等非手术治疗可以在一段时间内缓解症状,许多人借助这些方法能在数月甚至更长时间内应对良好。如果需要手术,反式肩关节置换术在治疗这种病症方面有着良好的记录。它能够可靠地缓解疼痛并恢复活动能力,因为三角肌接管了缺失肌腱原本承担的工作。大多数术前活动能力正常的人术后能够恢复其活动,重返运动也很常见。
术后恢复需要时间和努力。在物理治疗师指导下尽早进行主动康复是安全且有效的,与较缓慢、较谨慎的方式相比,它可以更早带来益处。物理治疗在最初几周之后也同样重要:它决定了您能恢复多少活动度,以及在数月乃至数年后您应对日常活动的难易程度。有些人发现自行进行的居家训练计划与正式的监督性训练效果相当,因此做好这部分康复的方法不止一种。
请对手术能做到什么、不能做到什么抱有现实的期望。因肩袖关节病而置换的肩关节,其起点比因单纯关节炎而置换的肩关节更差,因此效果往往比这些较简单的病例稍逊一些。任何肩关节置换术都可能发生并发症。最常见的是关节不稳定(即关节以不应有的方式移动)和感染。部分并发症一旦发生可以得到成功治疗;翻修手术(即重做部分或全部置换)仍能在疼痛、活动度和功能方面带来切实改善,尽管效果通常不如第一次手术。
您自身的起点很重要。术前肩部的状况是预测术后肩部状况的最有力因素之一,我们会据此与您一起规划康复。
何时就医¶
肩袖关节病通常进展缓慢,因此大多数人是在肩部开始限制日常生活时前来就诊,而不是作为急诊。如果疼痛在休息和服用简单止痛药后仍未缓解、在数周内逐渐加重,或在夜间将您痛醒,请要求专科医生评估。如果无力或肩部顶端的圆形隆起使您无法工作或使用手臂,也同样适用。
有些信号需要当天就医。如果您的肩部变得发热、发红、肿胀并疼痛,尤其是伴有发烧时,或者您的手臂变得苍白、冰冷、发白或发蓝,请前往急诊科。手臂突然失去感觉或无法活动,也需要急诊评估。
如果您已经接受过肩关节置换术,并注意到肩峰基底部出现新的疼痛、新出现的无力,或疼痛突然加剧或功能丧失,请及时告诉我们。如果无法联系到诊所,请前往离您最近的急诊科。
深入探讨¶
Advanced reading: the deeper science (optional)
本节内容超出了您做出自身治疗决策所需的深度。肩袖撕裂性关节病和巨大不可修复撕裂值得额外阅读,因为针对这两种情况所描述的手术数量本身便是最具信息量的事实:当多种术式相互竞争时,没有任何一种被明确证明为最佳。
所有治疗均有一定效果,但无一明确更优¶
在2,000例患者中,针对不可修复的后上肩袖撕裂所研究的十一种不同治疗方式均显示出具有临床意义的治疗效果,但患者特征、联合干预措施、结局报告及随访时长的差异使得任何可靠的比较都变得复杂 [1]。另一项针对3,363例患者的独立综述发现,所有六种非关节置换选项在一年或更长时间后均使关节活动度和患者报告结局产生具有统计学意义的改善,且翻修率较低 [2]。
十一种方式,六种选项,均产生改善,无一明确更优。这种模式通常表明两件事:自然病程本身包含一定程度的改善,且研究异质性过大,无法区分不同治疗的效果。
早期改善,后期下降¶
有一项发现值得强调,因为它在短期报告中容易被忽视。在 2,790 例接受上关节囊重建、部分修复、移植物间置及相关手术的患者中,尽管再撕裂率高,所有术式在肩关节评分上均显示出显著的初始改善,且肩关节评分在中长期随访中可能出现下降 [3]。
因此,同一手术在一年时可能看起来是成功的,而在五年时则可能不那么成功。当阅读某术式效果良好的报告时,随访间隔与数值本身同样重要。
2026 年一项针对 4,963 例患者的分析试图通过按失败率而非结果评分对治疗进行排名来解决这一问题。虽然该研究未确定出单一的最佳治疗方案,但产生了一个可靠性层级 [4]。当早期评分趋于一致时,按失败率排名可以说是更诚实的衡量标准。
为何肩袖缺失后关节会发生磨损¶
该机制解释了为何这是一种独立疾病,而不仅仅是巨大的撕裂。当三角肌上举时,肩袖将肱骨头保持在关节盂的中心位置。失去肩袖后,三角肌的牵拉会将肱骨头向上推,使其撞击肩峰的下表面。
这会产生一种特征性的模式:在X光片上肱骨头向上移位,肩峰与肱骨头在原本不应接触的部位相互磨损,关节面继发性退化。这是由力学因素而非原发性关节疾病引起的关节炎,因此,如果不解决力学问题而仅治疗关节炎,是无效的。
这也是反式肩关节置换术解决了该问题的原因,它使得仅靠三角肌即可发挥作用,无需依赖肩袖。当关节病已确立时,该手术在单独页面中介绍。
以正确的预期解读结局数据¶
解读结果时需留意一点:在此类适应证下,反式置换术后的结局相较于其他适应证有所下降,涉及 6,698 例患者 [5]。该手术是有效的,但不应期望因肩袖关节病而进行置换的肩关节能达到因单纯性关节炎且肩袖完整而进行置换的肩关节的效果,因为前者的起始状况更差。
参考文献¶
[1] Kooistra B, Gurnani N, Weening A, van den Bekerom M, van Deurzen D. 所有针对不可修复的后上肩袖撕裂的治疗方式证据水平均较低。Knee Surg Sports Traumatol Arthrosc. 2019;27(12):4038-48. https://doi.org/10.1007/s00167-019-05710-0
[2] Hughes JD, Davis B, Whicker E, Sprowls GR, Barrera L, Baradaran A, et al. 针对巨大且不可修复的肩袖撕裂的非关节置换选择改善了患者报告结局。Knee Surg Sports Traumatol Arthrosc. 2022;31(5):1883-902. https://doi.org/10.1007/s00167-022-07099-9
[3] Davies A, Singh P, Reilly P, Sabharwal S, Malhas A. 上关节囊重建、部分肩袖修复、移植物间置、肩峰下球囊间隔物或结节成形术:系统综述。J Orthop Surg Res. 2022;17(1). https://doi.org/10.1186/s13018-022-03411-y
[4] Cooke SP, Koh JL, Amirouche F. 针对大型至巨大不可修复肩袖撕裂的治疗选择失败率分析。J Shoulder Elbow Arthroplasty. 2026;10(1-2):100019. https://doi.org/10.1016/j.jsea.2026.100019
[5] Yazdanpanah S, Soth BT, Eskew JR, Dancy M, Fu MC, Taylor SA, et al. 针对肩袖撕裂关节病行反式全肩关节置换术后临床及功能结局下降:系统综述。JSES Rev Rep Tech. 2026;6(2):100691. https://doi.org/10.1016/j.xrrt.2026.100691
Evidence & references
This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.
Overview¶
- Favorable clinical outcomes can be achieved after hemiarthroplasty for glenohumeral arthritis complicated by massive rotator cuff tears [1].
- Shoulder arthroplasty restores shoulder function well in both osteoarthritis and rotator cuff tear arthropathy [2].
- Reverse total shoulder arthroplasty provides comparable clinical outcomes across indications of irreparable rotator cuff tear, rotator cuff tear arthropathy, and primary osteoarthritis at 2 years [3].
- Patients with rotator cuff arthropathy associated with a significant loss of deltoid function may be better managed with glenohumeral arthrodesis [4, 5].
- The short-term results of subacromial balloon spacers for management of massive rotator cuff tears demonstrate clinically relevant improvements in shoulder range of motion and substantial improvements in patient-reported outcome measures [6].
- Patients with irreparable massive rotator cuff tears without the presence of osteoarthritis have a high likelihood of achieving a painless shoulder and functional improvements after reverse shoulder arthroplasty [7].
- In patients with rotator cuff-intact glenohumeral osteoarthritis, anatomic total shoulder arthroplasty and reverse total shoulder arthroplasty demonstrated similar short-term to midterm clinical outcomes after propensity score matching, with no significant differences observed across age strata [8].
- Bipolar arthroplasty is indicated for patients with rotator cuff arthropathy [11].
- The functional results of large head or any type of hemiarthroplasty are unpredictable in rotator cuff tear arthropathy, but pain relief, the primary goal of surgery, is a predictable result of surgery [12].
- In selected and willing patients, deltoid release can be an efficacious alternative to shoulder prosthesis or to other technically complicated procedures [14].
- The most common postoperative complication in humeral head replacement was rotator cuff tearing, found in 23 (18.1%) of 127 shoulders [16, 25].
- Differences in postoperative patient-reported outcomes and improvement from baseline demonstrate a trend toward lower outcomes in patients with prior rotator cuff repair, but these differences may be below the minimal clinically important difference [17].
- Reverse shoulder arthroplasty provides optimal outcomes with low complication rates across a short term of follow-up for glenohumeral osteoarthritis with an intact rotator cuff [20].
- Irrespective of tissue source, superior capsular reconstruction serves as a reasonable joint-preserving option for massive, irreparable rotator cuff tears, with favorable short- to midterm improvements in patient-reported outcomes and range of motion [26].
- Under optimal circumstances, simultaneous shoulder arthroplasty is feasible [38].
- Tenodesis at the time of primary rotator cuff repair may be associated with a reduction in the utilization of ipsilateral shoulder revision surgery rates [41].
- Nonprosthetic glenoid arthroplasty is being expanded to individuals who do not want the risk of a glenoid prosthesis regardless of age for the treatment of glenohumeral arthritis [55].
- All six nonarthroplasty treatment options for irreparable rotator cuff tears resulted in statistically significant improvements in range of motion and patient-reported outcomes at 1 year follow-up or more, with low rates of revision and conversion to arthroplasty [56].
- Hemiarthroplasty does not provide for a successful outcome in all patients with rotator cuff arthropathy [60].
Anatomy & Pathophysiology¶
Bony Anatomy¶
- The glenoid is a convex structure of shallow depth shaped like an inverted pear [74].
- The glenoid articular surface radius of curvature is 2 to 3 mm larger than that of the humeral head [86].
- The average neck-shaft angle of the proximal humerus is 45 degrees (±5 degrees), with a range of 30 to 50 degrees [86].
- Arthritic shoulders have a flatter neck-shaft angle close to 50 degrees [86].
- The superior margin of the humeral head articular surface is normally superior to the top of the greater tuberosity by 8 to 10 mm [86].
- The distance from the lateral base of the coracoid process to the lateral margin of the greater tuberosity is called the lateral humeral offset [86].
- A significant decrease in lateral humeral offset reduces the lever arms for the deltoid and supraspinatus muscles, weakening abduction and impairing function [86].
- A significant increase in lateral humeral offset causes excessive tension on the soft tissues, resulting in loss of motion and likely accelerating polyethylene wear [86].
- Humeral articular malposition of more than 4 mm leads to increased subacromial contact [86].
- An offset of 8 mm in any direction significantly decreases passive range of motion [86].
- Proximal humeral retroversion is highly variable, ranging from 0 to 55 degrees depending on the method used for measurement [86].
- The glenoid averages 5° of retroversion in relation to the axis of the scapular body [77].
- The humeral head averages 19° of retroversion and 41° of inclination (neck-shaft angle) [77].
- The articular head of the humerus is spherical and has a diameter of 37 to 57 mm [74].
- The most superior portion of the articular surface of the humeral head averages 8 mm above the greater tuberosity [74].
- The humeral version averages 29.8 degrees (range, 10 to 55 degrees) [74].
- The head is inclined approximately 130 degrees with respect to the humeral shaft [74].
- The neck-shaft angle measures an average of 135 degrees, and the humeral head is retroverted an average of 30 degrees [75].
- The glenoid cavity is a shallow socket, approximately one third the size of the humeral head [75].
- The linear correlation between glenoid inclination and acromial angle suggests the presence of a balance between the glenoid inclination and the acromial coverage in a healthy shoulder [39].
- The critical shoulder angle should be considered as a “combined shoulder angle” with balanced contributions of glenoid inclination and acromial angle in shoulder arthritis progression [120].
Soft Tissue Anatomy¶
- The rotator cuff consists of four muscles: the subscapularis, supraspinatus, infraspinatus, and teres minor [75].
- The teres major is not a rotator cuff muscle [75].
- The cuff muscles serve as depressors of the humeral head to allow the deltoid to efficiently abduct the humerus [75].
- The infraspinatus and teres minor are external rotators, while the subscapularis is an internal rotator of the humerus [75].
- The greater tuberosity provides attachment for the supraspinatus, infraspinatus, and teres minor muscles [75].
- The lesser tuberosity contains the attachment of the subscapularis muscle [75].
- The rotator cuff is a sheet of conjoined tendons closely applied over the shoulder capsule and inserting mainly into the greater tuberosity of the humerus, with the subscapularis inserted into the lesser tuberosity [82].
- The coracoacromial arch is formed by the acromion process posterosuperiorly, the coracoid process anteriorly, and the coracoacromial ligament joining them [82].
- The subacromial bursa separates the tendons from the coracoacromial arch and allows them to glide [82].
- The rotator interval is defined medially by the base of the coracoid, superiorly by the supraspinatus tendon, and inferiorly by the subscapularis tendon [77].
- The rotator interval contains the coracohumeral ligament, the superior glenohumeral ligament, and the intra-articular portion of the long head of the biceps tendon [77].
- Laxity of the rotator interval results in inferior laxity (the sulcus sign), and contracture of the interval is seen with adhesive capsulitis [77].
- The coracohumeral ligament restricts external rotation in adduction and is a static restraint to inferior and posterior translation in adduction and external rotation [77].
- The superior glenohumeral ligament is a primary static restraint against anterior translation with the arm at the side [77].
- With the coracohumeral ligament, the superior glenohumeral ligament forms a pulley that provides restraint against medial subluxation of the long head of the biceps tendon [77].
- The middle glenohumeral ligament is a primary static restraint against anterior translation with the arm in external rotation and 45° of abduction [77].
- The anterior band of the inferior glenohumeral ligament is a primary static restraint against anterior-inferior dislocation of the glenohumeral joint in 90° of abduction and external rotation [77].
- The posterior band of the inferior glenohumeral ligament is a primary static restraint against posterior-inferior translation in internal rotation and adduction [77].
- The glenoid labrum provides concavity and up to 50% of marginal glenoid socket depth [77].
- The fibrocartilaginous glenoid labrum deepens the socket by 50% around the humeral head and increases stability [87].
- The glenoid articular surface and the labrum combine to create a socket that is approximately 9 mm deep in the superoinferior direction and 5 mm deep in the anteroposterior direction [87].
- Adding the glenoid labrum increases the glenoid surface to 75% of the humeral head vertically and 57% horizontally [87].
- The tendinous insertions of the rotator cuff muscles, the articular capsule, the coracohumeral ligament, and the glenohumeral ligament complex blend into a confluent sheet before insertion into the humeral tuberosities [87].
- The tendons of the infraspinatus and supraspinatus muscles join approximately 15 mm proximal to their insertion and cannot be readily separated by blunt dissection [87].
- The infraspinatus and teres minor fuse near their musculotendinous junctions [87].
- The supraspinatus and subscapularis tendons join as a sheath that surrounds the biceps tendon at the entrance of the bicipital groove [87].
- The roof of the biceps sheath consists of a portion of the supraspinatus tendon, and a sheet of the subscapularis tendon forms the floor [87].
- The coracoacromial ligament is a thick band of fibrous tissue extending from the coracoid process along the surface of the capsule to the tuberosities between the supraspinatus and subscapularis tendons [87].
- The coracoacromial ligament contributes to anterosuperior stability in rotator cuff deficiency and should be preserved with irreparable cuff tears to prevent anterosuperior escape [88].
- The subscapular bursa lies between the subscapularis tendon and the neck of the scapula and communicates with the joint cavity between the superior and middle glenohumeral ligaments [78].
- The subscapular bursa often houses loose bodies in the shoulder and is a region in which synovitis of the shoulder may be most intense [78].
- The humeroscapular motion interface lies between the inner structures of the proximal humerus, rotator cuff, coracohumeral ligament, and biceps tendon sheath and the superficial layer of the acromion, deltoid, coracoacromial ligament, coracoid process, and the conjoined tendon [80].
- Smooth, unrestricted motion at the humeroscapular motion interface is vital to shoulder mobility [80].
- The axillary nerve has an intimate relationship within the humeroscapular motion interface [80].
- The anterior and middle deltoid muscle receives sole innervation from the anterior branch of the axillary nerve [80].
- The posterior deltoid muscle innervation varies, with supply only from the anterior branch in 2.3% of cases, from the posterior branch in 8.5%, and from both branches in 89.1% [80].
- The proximal humerus receives its blood supply from the anterior and posterior humeral circumflex branches from the third division of the axillary artery [74].
- The anterior humeral circumflex artery provides vascular inflow to the humeral head by way of its terminal anterolateral branch known as the artery of Laing (also known as the arcuate artery) [74].
- Injury to the arcuate artery may result in osteonecrosis of the humeral head [74].
- Additional extraosseous collateral branches can permit humeral head perfusion despite complete ligation of the arcuate artery [74].
- The anterolateral ascending branch of the anterior humeral circumflex artery provides the primary blood supply to the humeral head [77].
- The terminal intraosseous portion of the artery enters at the proximal aspect of the intertubercular groove as the arcuate artery [77].
- Quantitative assessment has shown that 64% of the humeral head blood supply arises from the posterior humeral circumflex artery [81].
- The scapula is suspended by muscles alone and reflects the adaptive development of the shoulder [84].
- Broadening of the infraspinatus fossa has resulted in a change in the vector of muscle pull from the axillary border of the scapula to the glenoid fossa [84].
- This adaptation allows the infraspinatus and teres minor muscles to be more effective in their roles as depressors and external rotators of the humeral head [84].
- The acromion has enlarged over time, reflecting the increasing role of the deltoid muscle in shoulder function [84].
- The broader attachment of the deltoid on the acromion and its more distal insertion on the humerus have increased its mechanical advantage in shoulder motion [84].
- With the shoulder in 90 degrees of abduction, the coracoid extension over the glenohumeral joint can mechanically limit anterior translation of the humerus relative to the glenoid [84].
Pathophysiology¶
- Cuff tear arthropathy (CTA) is the final stage of the shoulder impingement syndrome spectrum [102].
- CTA affects patients with long-term insufficient massive rotator cuff tears, superior migration of the humeral head toward the acromion, subchondral osteoporosis, humeral head collapse, and painful debilitating shoulder arthritis [102].
- CTA was initially known as Milwaukee shoulder syndrome due to the rapidly progressive destruction of cartilage and bone, noninflammatory joint effusion containing calcium hydroxyapatite crystals, synovial hyperplasia, and multiple loose bodies [102].
- CTA affects women (3:1 female to male ratio), over 70 years old, more commonly on the dominant shoulder [102].
- Risk factors for CTA include chronic rotator cuff tears, hemorrhagic shoulder (oral anticoagulants and hematologic diseases), rheumatic disease, and crystal-induced arthropathy [102].
- Neer suggested mechanical, nutritional, and crystal-induced arthropathy pathways for CTA, but no definitive pathogenesis has been identified [102].
- Mechanical factors in CTA include insufficient cuff, superior migration of the humeral head, instability, eccentric wear of the glenoid, humeral head deformity, and decreased shoulder function [102].
- Nutritional factors in CTA include hypomobility-induced cartilage atrophy, poor nutrition (decrease in glycosaminoglycans), dehydration, and subchondral osteoporosis [102].
- Crystalline-induced arthropathy in CTA involves synovial-based matrix proteins degradation destroying rotator cuff tendons and cartilage, with end-stage calcium-phosphate crystal deposition [102].
- A massive cuff tear induces both nutritional and mechanical factors that provide a logical explanation for the development of humeral head collapse [15].
- Hydroxyapatite is strongly related to the pathogenesis of Milwaukee shoulder syndrome, which is nearly identical to cuff tear arthropathy [15].
- CPPD crystal deposition can hasten the development of cuff tear arthropathy [15].
- Cuff tear arthropathy is defined as a combination of massive cuff tear, elevation and collapse of the humeral head, and damage to the glenohumeral joint [15].
- The dysfunction of the rotator cuff results in loss of the concavity-compression mechanism, instability, and a predictable wear pattern with superior humeral migration and ultimate acetabularization of the acromion [70].
- The reverse total shoulder design counteracts a rotator cuff-deficient system by changing the center of rotation of the native glenohumeral joint to one that is more distal and medial [70].
- Distalization of the humerus lengthens the lever arm of the deltoid and increases the resting tension of the muscle, thus increasing the compression between the glenosphere and humeral prosthesis [70].
- Medialization minimizes the shear forces experienced at the bone-base plate interface [70].
- The compressive, stabilizing force generated by deltoid pressing along the lateral aspect of the proximal humerus is referred to as deltoid wrapping [70].
- Impingement-rotator cuff tears are a spectrum of disease that start with tendinitis (20 to 35 years old), progress to tendinosis (35 to 45 years old), rotator cuff tears (>45 years old), and, if not treated, evolve to cuff arthropathy (>65 years old) [118].
- Intrinsic degeneration in rotator cuff tears involves age-related (>60 years old) changes in collagen, proteoglycan, water content, and vascularity (tendinosis), usually involving the supraspinatus and infraspinatus starting on the articular side [118].
- Extrinsic rotator cuff tears result from chronic impingement on the coracoacromial arch, usually starting on the bursal side of the tendon, and may be associated with a hook-shaped acromion [118].
- Acute traumatic rotator cuff tears occur after a fall and/or dislocation of the shoulder in patients under 40 years old [118].
- The hypovascular critical zone is located on the articular side of the rotator cuff close to the insertion on the greater tuberosity [118].
- Microangiographic studies showed an area of hypovascularity near Codman’s “critical zone” just proximal to the supraspinatus insertion into the greater tuberosity [101].
- This hypoperfusion is believed to initiate degenerative changes, which subsequently lead to calcification or susceptibility to tearing [101].
- Other histologic studies showed no evidence of inadequate vascularization, and the supraspinatus, including the critical zone, was found to be well supplied with an anastomosis of vessels [101].
- One histologic study demonstrated neovascularization and neoinnervation in calcific tendonitis, with an associated substantial inflammatory response as the cause of pain [101].
- Calcific tendinitis follows a definite progression in most patients, with resolution seen in almost all of them [101].
- The precalcification stage of calcific tendinitis involves fibrocartilaginous metaplasia at the site of predilection for calcification, possibly a site with diminished blood supply [101].
- During the calcification stage, calcium is deposited into matrix vesicles, which are excreted by the cells and coalesce into larger calcium deposits [101].
- The resorption phase of calcific tendinitis involves an inflammatory response and is exquisitely painful [101].
- The precise pathogenesis of calcific tendinitis remains unclear, but an active, cell-mediated process is widely accepted [116].
- The precalcific stage of calcific tendinitis consists of predominantly fibrocartilaginous metaplasia presumably within less vascular areas of the tendon [116].
- In the formative phase of the calcific stage, matrix vesicles unite to form calcium hydroxyapatite deposits that are separated by fibrocollagenous tissue [116].
- Without a clear trigger, the resorption phase involves an inflammatory response [116].
- Pain in calcific tendinitis is variable during the proliferative phase and is correlated with the macrophage activity during the resorptive phase [116].
- Rotator cuff pathology spans a spectrum of severity that includes rotator cuff tendinopathy, partial-thickness tears, full-thickness tears, and rotator cuff arthropathy [93].
- The requisites for normal cuff function include healthy, strong cuff muscles, normal capsular laxity, intact cuff tendons, a smooth contour of the underside of the coracoacromial arch, a thin, lubricating bursa, a smooth upper surface of the cuff and tuberosities, and concent
Classification¶
- The hypothesis proposed by Neer concerning the pathomechanics of cuff tear arthropathy is that a massive cuff tear induces both nutritional and mechanical factors that provide a logical explanation for the development of humeral head collapse [15].
- McCarty described a shoulder condition called the Milwaukee shoulder syndrome, which was nearly identical to cuff tear arthropathy, and emphasized that hydroxyapatite was strongly related to the pathogenesis of this shoulder condition [15].
- CPPD crystal deposition has been suggested to hasten the development of cuff tear arthropathy [15].
- Primary osteoarthritis is confirmed where glenohumeral joint narrowing is observed on radiographs, together with sclerotic osteophytes on the humeral head, and acromiohumeral distance >6 mm [33].
- Secondary osteoarthritis is confirmed where glenohumeral joint narrowing is observed on radiographs, together with proximal humeral migration, as a consequence of large or massive rotator cuff tears observed on MRI or CTA [33].
- Secondary osteoarthritis includes cuff tear arthropathy (Hamada stage 5), as well as early stage of OA combined with mRCT (Hamada stages 1 and 2), and shoulders with no humeral necrosis [33].
- Fatty infiltration of the supraspinatus, infraspinatus, and subscapularis is graded using the classification of Goutallier et al [33].
- Fatty infiltration of the rotator cuff muscles is dichotomized as either functional (Goutallier classification 0, 1, or 2) or nonfunctional (Goutallier classification 3 or 4) [33].
- The Walch classification is used to assess glenoid morphology in the transverse plane [33].
- The Hamada classification is used to confirm secondary osteoarthritis due to rotator cuff tears [33].
Clinical Presentation¶
- Hydroxyapatite is strongly related to the pathogenesis of Milwaukee shoulder syndrome, which was described as nearly identical to cuff tear arthropathy [15].
- CPPD crystal deposition may hasten the development of cuff tear arthropathy [15].
- Overhead function is experienced only in cases when the rotating cuff was intact or properly reconstructed [13].
- Rotator cuff deficiency and instability are important factors for a poor result in shoulder arthroplasty for non-tumorous glenohumeral desintegration [128].
- The glenoid should not be resurfaced in the setting of a deficient rotator cuff, significant bone loss, or a young active patient because of the increased failure rates in these populations [19].
- Favorable clinical outcome can be achieved after hemiarthroplasty for glenohumeral arthritis complicated by massive rotator cuff tears [1].
- The functional results of large head or any type of hemiarthroplasty are unpredictable in rotator cuff tear arthropathy, but pain relief is a predictable result of surgery [12].
- Significant theoretical advantages exist for the BiPolar shoulder design which are particularly important in cases of cuff tear arthropathy [42, 62].
- Results with the Neer Shoulder prosthesis are adversely influenced by cuff tear arthritis, with a Constant Score of 45 per cent [18].
- In cadaveric studies, subacromial balloon spacers resist superior humeral head migration and reduce subacromial pressure [22].
- Arthroscopic debridement is one of the useful methods for osteoarthritis with massive rotator cuff tears, but its utility is limited [40].
- Patients with irreparable massive rotator cuff tears without presence of osteoarthritis have a high likelihood of achieving a painless shoulder and functional improvements after reverse shoulder arthroplasty [7].
- Reverse total shoulder arthroplasty can provide reliable improvement in clinical outcomes regardless of preoperative diagnosis, with few differences across diagnostic groups regarding preoperative to postoperative improvement [133].
- Within a group of patients with primary glenohumeral degenerative joint disease, shoulder arthroplasty was effective within a relatively short time frame in improving the patients' assessment of both shoulder function and overall health status [27].
- Shoulder function and outcome scores showed no significant deterioration between 5 and 20 years of follow-up after reverse total shoulder arthroplasty for rotator cuff dysfunction [35].
- Patients undergoing primary reverse shoulder arthroplasty demonstrated clinically significant improvements in both range of motion and clinical outcome scores [63].
- The most common diagnosis in a systematic review of patient satisfaction after reverse total shoulder arthroplasty was cuff tear arthropathy (25.8%) [30].
- Cuff tear arthropathy was the most common indication for reverse shoulder arthroplasty in a systematic review of outcomes following failed rotator cuff repair [31].
- Reverse total shoulder arthroplasty has continued to increase in clinical utility and popularity as an effective treatment for cuff tear arthropathy [121].
Investigations¶
Plain Radiography¶
- The purpose of shoulder imaging is to help establish the diagnosis, determine the severity of the pathoanatomy, assist in surgical planning, and enable the surgeon to illustrate the condition of the shoulder to the patient [49].
- Standardized plain films are almost always sufficient to garner the information needed for shoulder arthroplasty planning [49].
- The first key radiographic view is the anteroposterior (AP) view in the plane of the scapula, taken so that the x-ray beam passes through the glenohumeral joint [49].
- The AP view in the plane of the scapula shows the superoinferior position of the humeral head relative to the glenoid, the presence of osteophytes on the humeral head and glenoid, narrowing of the joint space, and the degree of medial displacement of the humerus in relation to the lateral acromial line [49].
- The AP view also demonstrates the quality of the humeral and glenoid bone, the presence of loose bodies, and whether there is humeral head collapse or deformity [49].
- The second key radiographic view is the axillary view taken with the arm in the functional position of elevation in the plane of the scapula [49].
- The axillary view is oriented so that both the spinoglenoid notch and the scapular neck are visible [49].
- The axillary view shows a different perspective of the humeral anatomy, the amount of glenoid bone, the shape of the glenoid, its version in relation to the plane of the scapula, and the relationship of the humeral head to the glenoid fossa [49].
- The axillary view is referred to as the "truth view" because it demonstrates the glenohumeral relationships in the functional position of elevation [49].
- CT scans have the disadvantage of being taken with the arm in the adducted position, whereas the axillary truth view is taken in elevation [49].
- When taken properly, standardized anteroposterior and axillary views indicate the thickness of the cartilage space between the humerus and the glenoid, relative positions of the humeral head and the glenoid, presence of osteophytes, degree of osteopenia, and extent of bony deformity and erosion [49].
- Joint space narrowing is most evident on the axillary truth view as opposed to images made with the arm at the side [49].
- The axillary truth view can show posterior subluxation or "functional decentering" that is not evident in images taken with the arm at the side [49].
- The degree of posterior subluxation can be measured as the position of the center of the humeral head in relation to the plane of the scapula, the position of the center of the humeral head in relation to the glenoid face, or the point of contact of the humeral articular surface on the glenoid articular surface [49].
- The point of contact of the humeral articular surface on the glenoid articular surface reflects the degree of centering of the net humeral joint reaction force on the glenoid [49].
- Malcentering of the joint reaction force leads to posterior instability, posterior glenoid wear, and "rocking horse" loosening of prosthetic glenoid components [49].
- At least two X-ray views should be obtained: an anteroposterior in the plane of the glenoid and an axillary projection with the arm in abduction to show the relationship of the humeral head to the glenoid [91].
- The standard shoulder series should include orthogonal views of the shoulder, including a true AP view in the scapular plane, an AP view, an axillary view, and a scapular Y view [104].
- The true AP view in the scapular plane visualizes the anterior greater tuberosity in profile and can reveal proximal humeral migration when the arm is held in neutral rotation with the shoulder in slight abduction [104].
- The AP view with the arm held in internal rotation visualizes the posterior aspect of the greater tuberosity and the lesser tuberosity in profile [104].
- The axillary view enables determination of the humeral head position in the glenoid fossa and may detect occult, locked posterior shoulder dislocation [104].
- The axillary view is helpful in evaluation of glenoid morphology in glenohumeral osteoarthritis and provides good visualization of the coracoid process, acromion, and distal clavicle [104].
- The scapular Y view provides visualization of the coracoacromial arch and can reveal coracoacromial spurs associated with rotator cuff pathology [104].
- The scapular Y view is a reliable alternative for evaluation of glenohumeral subluxation and dislocation and can show scapular body abnormalities and acromial shape [104].
- The acromiohumeral distance is normally 7 to 14 mm [104].
- The width of the glenohumeral joint space should be symmetric superiorly and inferiorly [104].
- The coracoclavicular distance is normally 1.1 to 1.3 cm [104].
- Neer classified acromial morphology as type I (flat), type II (curved), and type III (hooked) [104].
- Type III acromial morphology has been shown to have a correlation with the presence of rotator cuff disease, although no direct causal relationship has been demonstrated [104].
- The glenohumeral offset ratio in normal shoulders can be reliably calculated from a single radiograph [168].
- Plain radiographs are appropriate for patients presenting with shoulder pain with any history of trauma, dislocation, night pain, or chronic shoulder pain [104].
- Arthritis, calcific tendinitis, and osteolysis of the distal clavicle can be observed on plain radiograph [100].
Computed Tomography¶
- CT imaging is frequently used to evaluate fractures of the shoulder, to assess for bony lesions in recurrent instability cases, or for preoperative templating for shoulder arthritis [100].
- CT with three-dimensional reconstructions is the advanced imaging study of choice for determining the extent of glenoid bone loss in the setting of shoulder instability [104].
- CT is helpful for planning fracture surgery and shoulder joint replacement [91].
- Although CT scans may offer a few degrees of increased precision in the measurement of glenoid version, this precision does not necessarily improve the quality of the surgery or the clinical outcome [49].
- Three-dimensional reconstructions can reveal fine details of the shoulder anatomy, but this additional information rarely changes the planning or conduct of the arthroplasty [49].
Magnetic Resonance Imaging¶
- MRI is useful to identify osteonecrosis of the humeral head, or a bone tumour [91].
- MRI can identify labral tears and rotator cuff tears, although the accuracy for these is enhanced by combining the scan with arthrography [91].
- MRI is the modality of choice for evaluating the rotator cuff, biceps, and subacromial/subdeltoid bursa [100].
- T1-weighted MRI can reveal Hill-Sachs lesions and is often used with magnetic resonance arthrograms to provide a more detailed picture of the joint surfaces [100].
- T2-weighted MRI provides better visualization of full thickness rotator cuff tears [100].
- Magnetic resonance accuracy in identifying labral and rotator cuff tears in the literature ranges from 70% to 100% [98].
- The acquired multi-planar imaging of MRI allows for the detailed evaluation of the glenoid, labrum, joint capsule, and rotator cuff in different planes [98].
- MR arthrography (MRA) refers to MRI of a joint that has been injected with an intra-articular contrast agent such as diluted gadolinium or saline solution [98].
- MRA increases the sensitivity for detecting tears and other lesions by distending the joint capsule and outlining the cartilage, ligaments, and labrum with contrast [98].
- MRA has proven utility by increasing both sensitivity and specificity in detecting injuries to the capsulolabral–ligamentous complex as compared to traditional MRI [98].
- In a meta-analysis of 6 studies including 4,667 shoulders, MRA had greater diagnostic test accuracy for the detection of glenoid labral lesions than MRI, with MRA sensitivity of 88% and specificity of 93% versus MRI sensitivity of 76% and specificity of 87% [98].
- Abduction and external rotation (ABER) of the arm is an alternative position utilized to increase the sensitivity and specificity for detecting anteroinferior labroligamentous injury [98].
- Limited range of motion or pain may prohibit patients from performing the ABER provocative maneuver [98].
- MRAs can demonstrate a patulous capsule on the coronal, sagittal, and axial imaging in patients with multidirectional instability [98].
- MRAs can be helpful in evaluating lesions of the rotator interval and other associated findings that may affect the eventual surgical plan [98].
- The presence of glenoid dysplasia, increased capsular cross-sectional area, and increased glenoid retroversion have been found to be associated with increased posterior labral tears and symptomatic instability [98].
- Glenoid retroversion was significantly increased in patients with symptomatic posterior labral tears, but there was no significant association between instability and increased humeral head subluxation [98].
- The diagnosis of multidirectional instability is a clinical one, and the need for expensive and/or invasive imaging should be weighed against the information that will be gained from these studies [98].
- MR arthrography is considered the benchmark for evaluation of labral tears and is rarely indicated for evaluation of rotator cuff pathology [100].
- When MRI or MR arthrography is contraindicated, such as in patients with a pacemaker or vascular clips, CT arthrography is indicated [100].
Ultrasonography¶
- Ultrasonography is a simple and accurate test for identifying rotator cuff tears and calcific tendinitis [91].
- Ultrasonography can be useful in guiding injections or barbotage, such as aspirating calcific deposits in the rotator cuff [91].
- Ultrasonography is a low-cost alternative to MRI and arthrography for evaluating both skeletal and soft-tissue structures of the shoulder [100].
- Ultrasonography can provide immediate, real-time visualization of the rotator cuff, biceps tendon, and calcific deposits [100].
- Ultrasonography can be used to measure the subacromial space and detect atrophy of rotator cuff muscles [100].
- As a result of providing images in real-time, ultrasonography can evaluate impingement in various positions and motions [100].
- Ultrasonography is highly operator dependent and is not as useful for evaluating labral tears or rotator cuff tears that are very small or larger than 3 cm [100].
- The most commonly performed joint examination using ultrasonography is the shoulder examination [89].
- Accuracy of rotator cuff ultrasonography depends on the skill of the scanner operator and an awareness of pitfalls that are encountered [89].
- Ten common pitfalls of rotator cuff ultrasonography have been identified to reduce overdiagnosis or underdiagnosis of rotator cuff pathology [89].
Arthroscopy¶
- Arthroscopy is useful for diagnosing and treating subacromial impingement, intra-articular lesions, detachment of the glenoid labrum and rotator cuff tears [91].
Treatment¶
Non-Operative Management¶
- Nonoperative modalities for shoulder arthritis include activity modification, NSAIDs, physical therapy focusing on capsular stretching, and corticosteroid injections [107].
- Any surgical treatment for glenohumeral arthritis should be preceded by an adequate trial of conservative management that includes activity modification, physical therapy, antiinflammatory medication, and corticosteroid injections [92].
- Injectable viscosupplementation is an additional nonoperative treatment option for glenohumeral arthritis, although there is a paucity of evidence that supports its use in the shoulder and it is not currently approved by the U.S. Food and Drug Administration for injection in joints other than the knee [92].
- The minimal duration of non-operative treatment prior to surgery for irreparable posterosuperior rotator cuff tears varied from 0 months to 6 months across studies, with 28 studies not reporting on prior non-operative treatment [137].
Arthroscopic and Joint-Preserving Procedures¶
- Arthroscopic debridement for glenohumeral arthritis lacks high-quality evidence to support its routine use [92].
- Arthroscopic debridement with a combination of subacromial decompression, tuberoplasty, subacromial bursectomy, and biceps tenotomy produces good functional outcomes and improvement in pain at mid to long term follow up for the low-demand population greater than 65 years of age looking for pain relief over substantial increase in function [162].
- Comprehensive arthroscopic management consists of glenohumeral débridement, capsular release, and removal of humeral osteophytes [107].
- The optimal treatment of glenohumeral arthritis in young patients is not firmly established [44].
- Arthroscopic repairs of chronic, massive rotator cuff tears, whether complete or partial, are associated with significant improvements in pain, function and objective outcome scores [36].
- Superior capsule reconstruction serves as a reasonable joint-preserving option for massive, irreparable rotator cuff tears, with favorable short- to midterm improvements in patient-reported outcomes and range of motion irrespective of tissue source [26].
- Superior capsule reconstruction is a useful treatment modality for patients with irreparable rotator cuff tears, associated with significantly improved functional outcome scores and preserved or increased mean acromiohumeral distance [160].
- Shoulder scores may decline at mid- to long-term follow-up for large and massive irreparable rotator cuff tears treated with superior capsule reconstruction, partial cuff repair, graft interposition, arthroscopic debridement, or balloon spacers [21].
- Subacromial balloon spacer implantation for patients with massive irreparable rotator cuff tears may achieve satisfactory outcomes between 3 months and 3 years of follow-ups [127].
- Patients undergoing subacromial spacer implantation for the treatment of massive irreparable rotator cuff tears have satisfactory outcomes at the 2- to 3-year follow-up with a low rate of complications [58].
- Placement of the subacromial balloon spacer is a minimally invasive, technically simple procedure with favorable patient-reported outcomes at limited short-term follow-up [161].
- In selected and willing patients, deltoid release can be an efficacious alternative to shoulder prosthesis or to other technically complicated procedures for symptomatic cuff tear arthropathy [14].
Hemiarthroplasty¶
- Hemiarthroplasty is an option for young and active patients with severe glenohumeral arthritis, but glenoid erosion and need for early revision have been challenges in this patient population [117].
- Hemiarthroplasty is associated with a high rate of glenoid erosion and revision, and its use should be limited to a young patient with severe glenohumeral arthritis and a high level of heavy activity [117].
- The authors are optimistic for the role of shoulder hemiarthroplasty with nonprosthetic glenoid arthroplasty in the treatment of glenohumeral arthritis and have begun to expand indications to individuals who do not want the risk of a glenoid prosthesis regardless of age [55].
- Evaluation of patients suggests that bipolar arthroplasty is indicated for patients with rotator cuff arthropathy [11].
Anatomic Total Shoulder Arthroplasty¶
- Anatomic total shoulder arthroplasty is the benchmark for surgical treatment of primary glenohumeral arthritis with an intact rotator cuff and ample glenoid bone stock [117].
- Both keeled and pegged glenoid components yield similar pain relief, functional gains, and shoulder motion across most patient-reported outcome measures in total shoulder arthroplasty for primary osteoarthritis [37].
- Primary total shoulder arthroplasty performed through the rotator interval allows access to the glenohumeral joint without sacrificing the integrity of the subscapularis complex, maintains soft tissue balancing, allows optimal placement of the glenoid component, and allows patients to be started on a nonrestrictive physical therapy regimen [69].
Reverse Total Shoulder Arthroplasty¶
- Reverse total shoulder arthroplasty provides comparable clinical outcomes across indications of irreparable rotator cuff tear, rotator cuff tear arthropathy, and primary osteoarthritis at 2 years, supporting its broad applicability [3].
- Reverse total shoulder arthroplasty can address multiple issues including poor rotator cuff function, instability, and poor glenoid bone stock and is the treatment of choice in severe cuff tear arthropathy, and revision arthroplasty in elderly patients [117].
- The complication rate of reverse total shoulder arthroplasty is higher than anatomic total shoulder arthroplasty and patients commonly achieve less internal rotation postoperatively [117].
- Differences in postoperative patient-reported outcomes and improvement from baseline demonstrate a trend toward lower outcomes in patients with prior rotator cuff repair undergoing reverse shoulder arthroplasty, but these differences may be below the minimal clinically important difference [17].
- The presence of os acromiale does not appear to have a negative impact on the clinical outcomes after surgery and reverse total shoulder arthroplasty remains a safe and effective treatment option [59].
- Pre-operative glenoid bone mineral density varies significantly by indication for reverse total shoulder arthroplasty [139].
- Reverse shoulder arthroplasty provides the least benefit in forward flexion among multiple surgical treatments for massive irreparable rotator cuff tears in patients younger than 70 years of age [65].
- The postoperative rehabilitation protocol for reverse total shoulder arthroplasty generally occurs in 4 phases: 0 to 2 weeks (shoulder immobilizer with abduction pillow, non-weight-bearing), 2 to 6 weeks (active and passive ROM exercise), 6 to 16 weeks (weight-bearing as tolerated, strengthening exercises), and 16 to 24 weeks (gradual return to full activities) [66].
- In the overall study population of a systematic review on patient satisfaction after reverse total shoulder arthroplasty, the most common diagnosis was cuff tear arthropathy at 25.8%, followed by glenohumeral osteoarthritis at 20.6%, and rotator cuff tear at 19.4% [30].
- Within the subset of patients stratified by diagnosis in a systematic review on patient satisfaction after reverse total shoulder arthroplasty, the most common diagnoses were glenohumeral osteoarthritis at 34.5%, cuff tear arthropathy at 33.4%, and massive rotator cuff tear at 32.1% [30].
Arthrodesis¶
- Shoulder arthrodesis remains an alternative for failed prosthetic reconstructions, combined rotator cuff and deltoid deficiency, paralytic disorders, brachial plexus palsies, infection, and intractable instability in a patient who is not a candidate for reverse total shoulder arthroplasty [107].
- The position of fusion for shoulder arthrodesis is 30 degrees of abduction, 30 degrees of forward flexion, and 30 degrees of internal rotation [107].
Contraindications and Special Considerations¶
- Contraindications to shoulder arthroplasty include nonfunctioning deltoid and rotator cuff deficiency, intractable instability (though reverse arthroplasty may still be indicated), active infection, Charcot arthropathy, and poor patient compliance [107].
- Nonarthroplasty surgical interventions for shoulder arthritis are generally reserved for relatively young patients [107].
Complications¶
Postoperative Complications and Revision Rates¶
- In a literature review of 782 reverse total shoulder arthroplasties (RTSAs), the rate of postoperative complications was 20% [159].
- In a series of 825 RTSAs performed between 1996 and 2013, there were 84 reinterventions, including 60 revision surgeries [159].
- The complication rate for revision RTSA was 33.3%, which was almost 3-fold higher than the 13.4% rate for primary RTSA [159].
- In a cohort of 127 shoulders treated for osteonecrosis of the humeral head, the most common postoperative complication was rotator cuff tearing, occurring in 23 (18.1%) of shoulders [16, 25].
- In a study of total shoulder arthroplasty with an uncemented glenoid component, radiolucencies were noted around the glenoid component and/or screws in 45% of shoulders [64].
- Glenoid loosening is the most common long-term complication of total shoulder replacement [10].
- In a systematic review and meta-analysis of patients over 70 without a full-thickness rotator cuff tear, higher revision rates were identified following anatomic total shoulder arthroplasty (aTSA) compared to reverse total shoulder arthroplasty (rTSA) [130].
- In patients with rotator cuff-intact glenohumeral osteoarthritis, aTSA and rTSA demonstrated similar short-term to midterm clinical outcomes with no significant differences observed across age strata [8].
- In a systematic review of 2879 shoulders, differences in postoperative patient-reported outcomes and improvement from baseline demonstrated a trend toward lower outcomes in patients with prior rotator cuff repair, but these differences may be below the minimal clinically important difference [17].
- In a systematic review of 2149 patients undergoing reverse shoulder arthroplasty following failed rotator cuff repair, 760 patients had a history of prior rotator cuff repair and 1389 did not [31].
Risk Factors for Fracture and Complications¶
- Risk factors for acromial and scapular fractures following reverse shoulder arthroplasty include osteoporosis, inflammatory arthritis, female gender, and previous rotator cuff repair [23].
- The most commonly cited risk factors for acromial stress fractures following rTSA include osteoporosis, rheumatoid arthritis, female sex, and rotator cuff arthropathy [54].
Functional Limitations and Contraindications¶
- Overhead function was experienced only in cases when the rotating cuff was intact or properly reconstructed [13].
- In patients younger than 50 years, clinical outcomes after total shoulder arthroplasty tended to decline, ultimately with a large number of unsatisfactory results [110].
- In patients older than 80 years, total shoulder arthroplasty is associated with an increased risk for perioperative medical complications [110].
Disease-Specific Complications and Outcomes¶
- In patients with cuff tear arthritis or post-traumatic arthritis, the use of the Neer Shoulder prosthesis is more difficult and adversely influences results, with a Constant Score of 45% in both categories [18].
- In a rare case of cuff tear arthropathy associated with chondrocalcinosis, microscopic examination of the subscapularis tendon stump revealed calcium deposition closely approximating those of CPPD crystal on X-ray diffraction analysis [15].
Recovery¶
Arthroplasty Outcomes¶
- Patients with irreparable massive rotator cuff tears without osteoarthritis have a high likelihood of achieving a painless shoulder and functional improvements after reverse shoulder arthroplasty [7].
- In patients with rotator cuff-intact glenohumeral osteoarthritis, anatomic total shoulder arthroplasty and reverse total shoulder arthroplasty demonstrated similar short-term to midterm clinical outcomes with no significant differences observed across age strata [8].
- Shoulder function and outcome scores showed no significant deterioration between 5 and 20 years of follow-up for reverse total shoulder arthroplasty for rotator cuff dysfunction [35].
- All 68 shoulders achieved satisfactory long term results in total shoulder replacement for the treatment of primary glenohumeral osteoarthritis [61].
- Results with the Neer Shoulder prosthesis are influenced by etiology, with excellent and good results predictable with osteoarthritis (Constant score: 75 per cent) and rheumatoid arthritis (Constant score: 59 per cent), while cuff tear arthritis and post-traumatic arthritis make the procedure more difficult and adversely influence the results (Constant Score: 45 per cent in both categories) [18].
- Patients with prior rotator cuff repair undergoing reverse shoulder arthroplasty have worse postoperative functional scores and pain scores than those without prior repair [68].
- Patients in the proximal humerus fracture cohort were less likely to report persistent shoulder pain at all evaluated time points compared to the osteoarthritis cohort, suggesting that symptom relief following treatment of traumatic pathology may differ fundamentally from that of chronic degenerative disease [173].
Complications and Risks¶
- Glenoid loosening remains the most common long-term complication of total shoulder replacement [10].
- The most common postoperative complication was rotator cuff tearing, found in 23 (18.1%) of 127 shoulders in a study of osteonecrosis of the humeral head replacement [16].
- Further long-term studies are needed to assess durability for stemless versus stemmed reverse total shoulder arthroplasty as primary treatment in the elderly [140].
Joint-Preserving and Alternative Procedures¶
- Irrespective of tissue source, superior capsule reconstruction serves as a reasonable joint-preserving option for massive, irreparable rotator cuff tears, with favorable short- to midterm improvements in patient-reported outcomes and range of motion [26].
- Shoulder scores may decline at mid- to long-term follow-up for superior capsule reconstruction, partial cuff repair, graft interposition, arthroscopic debridement or balloon spacers for large and massive irreparable rotator cuff tears [21].
- Early results for meniscal allograft interposition arthroplasty for the arthritic shoulder appear promising, and the procedure does not preclude conversion to a total shoulder replacement or arthrodesis should this become necessary in the future [174].
Technical and Surgical Considerations¶
- Radiographs at 6 month follow-up demonstrate a space between the humeral head and the glenoid in all cases for surgical treatment of glenohumeral arthritis in the young patient [28].
- All glenoid components remain well fixed, with no loss of position noted, in patient-specific instrument-assisted structural glenoid bone grafting in reverse shoulder arthroplasty [67].
Key Evidence¶
- [L4] Favorable clinical outcome can be achieved after hemiarthroplasty for glenohumeral arthritis complicated by massive rotator cuff tears. [1] (10.1067/mse.2000.105138)
- [L3] Shoulder arthroplasty restores shoulder function well in both osteoarthritis (OA) and rotator cuff tear arthropathy (CTA). [2] (10.1016/j.otsr.2024.103852)
- [L3] rTSA provides comparable clinical outcomes across indications of irreparable rotator cuff tear, rotator cuff tear arthropathy, and primary osteoarthritis at 2 years, supporting its broad applicability. [3] (10.1016/j.jsea.2026.100080)
- [L4] Patients with rotator cuff arthropathy associated with a significant loss of deltoid function may be better managed with glenohumeral arthrodesis. [4] (10.1016/s1058-2746(95)80214-2)
- [L4] Patients with rotator cuff arthropathy associated with a significant loss of deltoid function may be better managed with glenohumeral arthrodesis. [5] (10.1016/s1058-2746(96)80227-8)
- [L4] The short-term results of subacromial balloon spacers for management of massive rotator cuff tears demonstrate clinically relevant improvements in shoulder range of motion and substantial improvements in patient-reported outcome measures. [6] (10.1016/j.arthro.2023.05.028)
- [L1] Patients with irreparable massive rotator cuff tears without presence of osteoarthritis have a high likelihood of achieving a painless shoulder and functional improvements after reverse shoulder arthroplasty. [7] (10.1016/j.jse.2017.03.039)
- [L3] In patients with rotator cuff-intact glenohumeral osteoarthritis, aTSA and rTSA demonstrated similar short-term to midterm clinical outcomes after PSM, with no significant differences observed across age strata. [8] (10.1016/j.jsea.2026.100050)
- [Paper] Glenoid loosening remains the most common long-term complication of total shoulder replacement. [10] (10.1097/00132589-200303000-00002)
- [L4] Evaluation of these patients suggests that Bipolar arthroplasty is indicated for patients with rotator cuff arthropathy. [11] (10.1016/s1058-2746(97)90083-5)
- [L4] The functional results of large head or any type of hemiarthroplasty are unpredictable in rotator cuff tear arthropathy, but pain relief, the primary goal of surgery, is a predictable result of surgery. [12] (10.1016/s1058-2746(95)80213-4)
- [L4] Overhead function was experienced only in cases when the rotating cuff was intact or properly reconstructed. [13] (10.1016/s1058-2746(95)80151-0)
- [L4] The author believes that in selected and willing patients, deltoid release can be an efficacious alternative to shoulder prosthesis or to other technically complicated procedures. [14] (10.1097/01.bte.0000159728.28049.43)
- [L5] [15] (10.1016/s1058-2746(98)90111-2)
- [L4] The most common postoperative complication was rotator cuff tearing, found in 23 (18.1%) of 127 shoulders. [16] (10.1067/mse.2000.105126)
- [L4] Differences in postoperative patient-reported outcomes and improvement from baseline demonstrate a trend toward lower outcomes in patients with prior rotator cuff repair, but these differences may be below the minimal clinically important difference. [17] (10.1177/17585732241268712)
- [L4] Results with the Neer Shoulder prosthesis are influenced by the etiology: excellent and good results are predictable with osteoarthritis (Constant score: 75 per cent) and rheumatoid arthritis (Constant score: 59 per cent) while cuff tear arthritis and post-traumatic arthritis makes the procedure more difficult and adversely influence the results (Constant Score: 45 per cent in both categories). [18] (10.1016/s1058-2746(96)80401-0)
- [L5] The glenoid should not be resurfaced in the setting of a deficient rotator cuff, significant bone loss, or a young active patient because of the increased failure rates in these populations. [19] (10.1097/bte.0b013e3181e0b319)
- [L4] Reverse shoulder arthroplasty provides optimal outcomes with low complication rates across a short term of follow-up for glenohumeral osteoarthritis with an intact rotator cuff. [20] (10.1016/j.jse.2021.06.010)
- [L1] Shoulder scores may decline at mid- to long-term follow-up. [21] (10.1186/s13018-022-03411-y)
- [L1] In cadaveric studies, subacromial balloon spacers resist superior humeral head migration and reduce subacromial pressure. [22] (10.1016/j.asmr.2020.06.011)
- [L1] Other risk factors identified included osteoporosis, inflammatory arthritis, female gender, and previous rotator cuff repair. [23] (10.1016/j.xrrt.2025.08.015)
- [L4] The most common postoperative complication was rotator cuff tearing, found in 23 (18.1%) of 127 shoulders. [25] (10.1016/s1058-2746(00)90052-1)
- [L1] Irrespective of tissue source, SCR serves as a reasonable joint-preserving option for massive, irreparable rotator cuff tears, with favorable short- to midterm improvements in patient-reported outcomes and range of motion. [26] (10.1016/j.asmr.2020.09.002)
- [L4] The data presented indicate that within a group of patients with primary glenohumeral degenerative joint disease, shoulder arthroplasty was effective within a relatively short time frame in improving the patients' assessment of both shoulder function and overall health status. [27] (10.1016/s1058-2746(95)80203-7)
- [L4] Radiographs at 6 month follow-up demonstrate a space between the humeral head and the glenoid in all cases. [28] (10.1097/01.bte.0000135965.23606.f0)
- [L4] [30] (10.1016/j.jse.2024.03.036)
- [L1] [31] (10.1177/17585732231194785)
- [L3] [33] (10.1016/j.jse.2023.07.027)
- [L1] Shoulder function and outcome scores also showed no significant deterioration between 5 and 20 years of follow-up. [35] (10.1016/j.jse.2018.10.005)
- [L2] Arthroscopic repairs of chronic, massive RCTs, whether complete or partial, are associated with significant improvements in pain, function and objective outcome scores. [36] (10.1007/s00167-020-06190-3)
- [L2] Both designs yield similar pain relief, functional gains, and shoulder motion across most patient-reported outcome measures. [37] (10.5397/cise.2025.01480)
- [L5] Under optimal circumstances simultaneous shoulder arthroplasty is feasible. [38] (10.1016/s1058-2746(96)80400-9)
- [L4] However, the linear correlation between GI and AA suggests the presence of a balance between the glenoid inclination and the acromial coverage in a healthy shoulder. [39] (10.1016/j.jseint.2024.08.157)
- [L4] Arthroscopic debridement is one of the useful methods for osteoarthritis with massive rotator cuff tears, but limited. [40] (10.1016/s1058-2746(96)80524-6)
- [L3] This suggests that tenodesis at the time of primary rotator cuff repair may be associated with a reduction in the utilization of ipsilateral shoulder revision surgery rates. [41] (10.5435/jaaosglobal-d-24-00046)
- [L4] Significant theoretical advantages exist for the BiPolar shoulder design which are particularly important in cases of cuff tear arthropathy. [42] (10.1016/s1058-2746(96)80462-9)
- [L5] The optimal treatment of glenohumeral arthritis in young patients is not firmly established. [44] (10.1097/bte.0b013e31825ce947)
- [L4] The most commonly cited risk factors for ASFs following rTSA include osteoporosis, rheumatoid arthritis, female sex, and rotator cuff arthropathy. [54] (10.1016/j.jse.2025.02.032)
- [Paper] The authors are optimistic for its role in the treatment of glenohumeral arthritis and have begun to expand indications to individuals who do not want the risk of a glenoid prosthesis regardless of age. [55] (10.1097/bte.0b013e3181976bb9)
- [L4] All six nonarthroplasty treatment options for irreparable rotator cuff tears resulted in statistically significant improvements in range of motion and patient-reported outcomes at 1 year follow-up or more, with low rates of revision and conversion to arthroplasty. [56] (10.1007/s00167-022-07099-9)
- [L1] Patients undergoing subacromial spacer implantation for the treatment of massive irreparable rotator cuff tears have satisfactory outcomes at the 2- to 3-year follow-up with a low rate of complications. [58] (10.1016/j.arthro.2018.08.006)
- [L4] The presence of os acromiale does not appear to have a negative impact on the clinical outcomes after surgery and rTSA remains a safe and effective treatment option. [59] (10.1016/j.xrrt.2025.01.002)
- [L4] Hemiarthroplasty does not provide for a successful outcome in all patients with rotator cuff arthropathy. [60] (10.1016/s1058-2746(96)80079-6)
- [L4] All 68 shoulders achieved satisfactory long term results. [61] (10.1016/s1058-2746(96)80399-5)
- [L4] Significant theoretical advantages exist for the BiPolar shoulder design which are particularly important in cases of cuff tear arthropathy. [62] (10.1016/s1058-2746(95)80108-1)
- [L1] Additionally, patients demonstrated clinically significant improvements in both range of motion and clinical outcome scores. [63] (10.1016/j.jse.2022.06.005)
- [L4] Radiolucencies were noted around the glenoid component and/or screws in 45% of shoulders. [64] (10.1097/00132589-200412000-00002)
- [L3] Reverse shoulder arthroplasty provides the least benefit in forward flexion. [65] (10.1177/03635465231204623)
- [L3] [66] (10.5435/jaaosglobal-d-22-00264)
- [L4] All glenoid components remain well fixed, with no loss of position noted. [67] (10.1097/bte.0000000000000123)
- [L1] Patients with prior rotator cuff repair undergoing reverse shoulder arthroplasty have worse postoperative functional scores and pain scores than those without prior repair. [68] (10.1016/j.xrrt.2023.01.006)
- [L5] This novel approach is advantageous because it allows access to the glenohumeral joint without sacrificing the integrity of the subscapularis complex, maintains soft tissue balancing, allows optimal placement of the glenoid component, and patients can be started on a nonrestrictive physical therapy regimen. [69] (10.1097/bte.0b013e3181b170ed)
- [L4] [70] (10.2106/jbjs.rvw.23.00238)
- [L4] Thus, CSA should indeed be considered as a “combined shoulder angle.” [120] (10.1016/j.xrrt.2026.100812)
- [L1] [121] (10.1016/j.jse.2021.07.014)
- [L1] Subacromial balloon spacer implantation for patients with massive irreparable rotator cuff tears may achieve satisfactory outcomes between 3 months and 3 years of follow-ups. [127] (10.1007/s00167-019-05834-3)
- [L4] Rotator cuff deficiency and instability are important factors for a poor result. [128] (10.1016/s1058-2746(96)80409-5)
- [L1] Higher revision rates were identified following aTSA in our study population, although admittedly this is within retrospective studies. aTSA displayed equal functional results and postoperative complications compared to rTSA in patients over 70 without a full-thickness rotator cuff tear. [130] (10.1177/24715492231206685)
- [L4] Reverse total shoulder arthroplasty can provide reliable improvement in clinical outcomes regardless of preoperative diagnosis, with few differences across diagnostic groups regarding preoperative to postoperative improvement. [133] (10.1016/j.jse.2020.10.003)
- [L4] [137] (10.1007/s00167-019-05710-0)
- [L4] Pre-operative glenoid bone mineral density (BMD) varies significantly by indication for reverse total shoulder arthroplasty. [139] (10.1016/j.jseint.2026.101720)
- [L1] Further long-term studies are needed to assess durability. [140] (10.1177/17585732251388447)
- [L4] [159] (10.1016/j.otsr.2015.06.031)
- [L1] This review demonstrates that SCR is a useful treatment modality for patients with irreparable rotator cuff tears, associated with significantly improved functional outcome scores and preserved or increased mean AHD. [160] (10.1016/j.otsr.2019.07.022)
- [L4] Placement of the subacromial balloon spacer is a minimally invasive, technically simple procedure with favorable patient-reported outcomes at limited short-term follow-up. [161] (10.1177/2325967119875717)
- [L1] Arthroscopic debridement with a combination of subacromial decompression, tuberoplasty, subacromial bursectomy, and biceps tenotomy produces good functional outcomes and improvement in pain at mid to long term follow up for the low-demand population greater than 65 years of age looking for pain relief over substantial increase in function. [162] (10.1016/j.xrrt.2021.08.012)
- [L4] The evidence indicates that a fairly constant glenohumeral offset ratio in normal shoulders can be reliably calculated from a single radiograph. [168] (10.1016/s1058-2746(09)80050-5)
- [L3] Patients in the proximal humerus fracture (PHF) cohort were less likely to report persistent shoulder pain at all evaluated time points compared to the osteoarthritis (OA) cohort, suggesting that symptom relief following treatment of traumatic pathology may differ fundamentally from that of chronic degenerative disease. [173] (10.1016/j.jsea.2026.100012)
- [L5] Early results appear promising, and the procedure does not preclude conversion to a total shoulder replacement or arthrodesis should this become necessary in the future. [174] (10.1097/00132589-200112000-00004)
References¶
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