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Cannabis at CBD para sa Pananakit

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What the evidence does and doesn't show for cannabis and CBD in musculoskeletal pain, and practical and safety considerations.

Updated Sep 2026
Isang dahon ng cannabis.
Lalong dumarami ang nagtatanong tungkol sa cannabis at CBD para sa pananakit ng kalamnan at buto; patuloy pang nagbabago ang ebidensya at mga regulasyon. Kieran Hirpara 4.0

Ang pahinang ito ay isinalin ng makina at hindi pa nasusuri ng isang doktor. Ang bersyong Ingles ang siyang opisyal.

Ano ito

Saklaw ng gamot na batay sa cannabis ang mga produktong gawa mula sa halamang cannabis, kabilang ang cannabidiol (CBD) at THC. Ang CBD ay isang bahagi ng halaman na hindi nagdudulot ng "high". Ang THC ang bahaging nagdudulot nito. Dumarating ang mga produktong ito bilang langis, tableta o cream na maaari mong ipahid sa balat.

Minsan nagtatanong tungkol dito ang mga taong may pangmatagalang pananakit mula sa arthritis, pananakit ng nerbiyo (nerve pain), o pananakit pagkatapos ng operasyon. Maraming pasyente ang interesado. Sa isang survey, 80.9% ng mga taong nagpapatingin sa isang klinika para sa kamay at upper limb ang nagsabing isasaalang-alang nila ang paggamit ng medical cannabis [1]. Sa mga taong may pananakit ng gulugod, isa sa bawat tatlo ang gumagamit na nito [2]. Malaking bilang ng mga taong may wear-and-tear arthritis sa puno ng hinlalaki ang nagsabing interesado silang subukan ito [3].

Pinag-aaralan pa kung paano ito gumagana. May sariling sistema ang iyong katawan na tumutugon sa mga compound sa cannabis, at may papel ang sistemang ito sa kung paano mo nararamdaman ang sakit. Iniulat ng isang review na ang kasalukuyang ebidensya ay nagmumungkahi ng benepisyo at kaligtasan para sa pangmatagalang pananakit ng kalamnan, buto at nerbiyo [4]. Ngunit magkakahalo ang larawan. Walang natuklasang klinikal na mahalagang benepisyo ang mga trial para sa pananakit ng nerbiyo pagkatapos ng mga pinsala sa brachial plexus (isang pinsala dahil sa pagkabatak ng mga nerbiyong dumadaloy mula sa iyong leeg papunta sa iyong braso) [5]. Ang isang synthetic na anyo ng THC ay mukhang hindi nakapagpababa ng pag-inom ng opioid pagkatapos ng operasyong knee replacement [6].

May ilang paalala. Ang regular na paggamit ng cannabis ay naiugnay sa mas mataas na paggamit ng opioid pagkatapos ng joint replacement [7]. Ang mga taong may dokumentadong pagkadepende sa cannabis ay may mas mataas na tsansa ng mga problema sa sugat pagkatapos ng operasyon sa malalambot na tisyu ng kamay at pulso [8]. Kailangan pa ng mas maraming pananaliksik bago makapagbigay ng malinaw na payo para sa maraming kondisyon [9, 4].

Gumagana ba ito?

Ang tapat na sagot ay nakadepende ito kung para saan mo ito ginagamit. Para sa pangmatagalang pananakit ng kalamnan, buto at nerbiyo, iniulat ng isang review na ang kasalukuyang ebidensya ay nagmumungkahi ng benepisyo at kaligtasan ng mga gamot na batay sa cannabis [4]. Natuklasan din ng isang review na maaari itong makatulong sa pananakit ng nerbiyo sa mga braso at binti, malayo sa gulugod [11]. Ngunit partikular para sa mga kondisyon ng kamay at braso, sinasabi ng mga mananaliksik na kailangan pa natin ng mas maraming pag-aaral bago makabuo ng matibay na konklusyon [4].

May ilang nakapagpapalakas-loob na natuklasan kaugnay ng operasyon. Maaaring isama ang CBD sa isang pinagsamang plano para sa pain relief pagkatapos ng keyhole rotator cuff repair nang hindi nakasasama sa iyong paggaling sa maikli o mahabang panahon [12, 13]. Ibig sabihin nito ay hindi nito pinalala ang mga resulta, hindi na napatunayang pinabuti nito ang mga ito. Para sa mga tinedyer at batang adulto na sumasailalim sa keyhole surgery sa balakang, ang mga gumamit ng marijuana bago ang operasyon ay may parehong antas ng sakit, pangangailangan sa painkiller at paggaling gaya ng mga hindi gumamit [14].

Ang ilang natuklasan ay hindi gaanong positibo. Sa mga tinedyer na sumasailalim sa reconstruction ng ligament ng tuhod, ang mga nag-ulat ng paggamit ng marijuana ay mas madalas na kinailangang ma-admit nang magdamag dahil sa sakit at mas natagalan bago makabalik sa sports [15]. Kaya ang parehong substansya ay maaaring mukhang walang panganib sa isang sitwasyon at may problema sa iba.

Mabuting malaman kung sino ang karaniwang gumagamit nito. Ang mga taong sumasailalim sa keyhole surgery na nag-uulat ng paggamit ng cannabis ay kadalasang mas bata at mas madalas na lalaki [16]. At karamihan ng mga taong nagpapatingin sa isang klinika para sa kamay at upper limb ay nakikita ang medical cannabis bilang ligtas na opsyon para sa mga karaniwang problemang orthopaedic [1].

Ang pinaka-importanteng punto: may tunay na ebidensya para sa ilang gamit, magkakahalong ebidensya para sa iba, at wala pang magagandang trial para sa maraming kondisyon ng kamay at braso. Kung pinag-iisipan mo ito, tanungin ang iyong doktor kung ano ang sinasabi ng ebidensya para sa iyong partikular na problema.

Ano ang mga panganib?

Ang tapat na sagot ay nakadepende ang mga panganib sa iyong sitwasyon, at hindi saklaw ng pananaliksik ang bawat kaso. Para sa pananakit ng nerbiyo sa mga braso at binti, natuklasan ng isang review na maaaring makatulong ang mga gamot na batay sa cannabis [11]. Ngunit para sa pananakit ng nerbiyo pagkatapos ng mga pinsala sa brachial plexus (isang pinsala dahil sa pagkabatak ng mga nerbiyong dumadaloy mula sa iyong leeg papunta sa iyong braso), walang natuklasang klinikal na mahalagang benepisyo ang mga trial nang idagdag ang paggamot na batay sa cannabis sa karaniwang mga plano para sa pain relief [5].

Kaugnay ng operasyon, magkakahalo ang larawan. Maaaring isama ang CBD sa isang pinagsamang plano para sa pain relief pagkatapos ng keyhole rotator cuff repair nang hindi nakasasama sa iyong paggaling sa maikli o mahabang panahon [12, 13]. Natuklasan ng isang pag-aaral ng CBD na sinisipsip sa pamamagitan ng pisngi na maayos itong natiis ng katawan at nagpabawas ito ng sakit sa mga unang araw pagkatapos ng parehong operasyong iyon [17]. Ngunit para sa mga tinedyer na sumasailalim sa reconstruction ng ligament ng tuhod, ang mga nag-ulat ng paggamit ng marijuana ay mas madalas na kinailangang ma-admit nang magdamag dahil sa sakit at mas natagalan bago makabalik sa sports [15]. Ang mga taong may dokumentadong pagkadepende sa cannabis ay may mas mataas na tsansa ng mga problema sa sugat pagkatapos ng operasyon sa malalambot na tisyu ng kamay at pulso [8].

Para sa mga tinedyer at batang adulto na sumasailalim sa keyhole surgery sa balakang, ang mga gumamit ng marijuana bago ang operasyon ay may parehong antas ng sakit, pangangailangan sa painkiller at paggaling gaya ng mga hindi gumamit [14]. Tiningnan din ng mga mananaliksik kung binago ng pagsasama ng cannabis at nicotine ang panganib ng mga problema pagkatapos ng operasyon sa bali sa upper limb. Wala silang natuklasang malinaw na dagdag na epekto, ngunit sinasabi nilang maaaring hindi sapat ang laki ng pag-aaral para matukoy ang isang maliit na epekto [18].

May mga tunay na puwang sa kung ano ang alam. Natuklasan ng isang pag-aaral na hindi naapektuhan ng paggamit ng cannabis ang mga resulta pagkatapos ng operasyong hip replacement, bagaman sinasabi ng mga may-akda nito na kailangan pa rin ng mas maraming pag-aaral [10]. Sinasabi rin ng mga mananaliksik na kailangan pa ng mas maraming pag-aaral para sa maraming kondisyon ng kamay at braso [9, 4]. Kaya kung gumagamit ka ng cannabis o CBD, sabihin sa iyong doktor. Matitimbang nila kung ano ang sinasabi ng ebidensya para sa iyong partikular na operasyon o kondisyon, at kung ano ang hindi pa nito sinasabi.

Tama ba ito para sa iyo?

Walang simpleng oo o hindi rito. Maaaring sulit pag-isipan ang gamot na batay sa cannabis para sa pangmatagalang pananakit ng kalamnan, buto at nerbiyo, kung saan iniulat ng isang review na ang kasalukuyang ebidensya ay nagmumungkahi ng benepisyo at kaligtasan [4]. Maaari rin itong makatulong sa pananakit ng nerbiyo sa mga braso at binti, malayo sa gulugod [11]. Ngunit para sa maraming kondisyon ng kamay at braso, wala pang magagandang trial, kaya walang makapagsasabi nang tiyak kung makatutulong ito sa iyo [9, 4].

Kaugnay ng operasyon, nakadepende ang sagot sa iyong operasyon at sa iyong kasaysayan. Maaaring maging bahagi ang CBD ng isang pinagsamang plano para sa pain relief pagkatapos ng keyhole rotator cuff repair nang hindi nakasasama sa iyong paggaling [12, 13]. Ngunit kung regular kang gumamit ng cannabis, may ilang paalala. Ang regular na paggamit ay naiugnay sa mas mataas na paggamit ng opioid pagkatapos ng joint replacement [7]. At ang mga taong may dokumentadong pagkadepende sa cannabis ay may mas mataas na tsansa ng mga problema sa sugat pagkatapos ng operasyon sa malalambot na tisyu ng kamay at pulso [8]. Ang mga tinedyer na sumasailalim sa reconstruction ng ligament ng tuhod na nag-ulat ng paggamit ng marijuana ay mas madalas na kinailangang ma-admit nang magdamag dahil sa sakit at mas natagalan bago makabalik sa sports [15].

Kumpara sa karaniwang mga plano para sa pain relief, hindi pamalit ang gamot na batay sa cannabis. Para sa pananakit ng nerbiyo pagkatapos ng mga pinsala sa brachial plexus (isang pinsala dahil sa pagkabatak ng mga nerbiyong dumadaloy mula sa iyong leeg papunta sa iyong braso), walang natuklasang klinikal na mahalagang benepisyo ang mga trial nang idagdag ito sa karaniwang pangangalaga [5]. Ang isang synthetic na anyo ng THC ay mukhang hindi nakapagpababa ng pag-inom ng opioid pagkatapos ng operasyong knee replacement [6].

Mas detalyadong tinatalakay ng seksyon tungkol sa mga panganib sa itaas ang mga paalala. Kung pinag-iisipan mong subukan ito, pag-usapan muna ito kasama ng iyong doktor. Matitimbang nila kung ano ang sinasabi ng ebidensya para sa iyong partikular na problema, at kung ano ang hindi pa nito sinasabi. Dapat itong maging desisyong pinagsasaluhan mo at ng iyong doktor.

Ang pinaka-importanteng punto

Maaaring sulit pag-isipan ang gamot na batay sa cannabis para sa pangmatagalang pananakit ng kalamnan, buto at nerbiyo, kung saan iniulat ng isang review na ang kasalukuyang ebidensya ay nagmumungkahi ng benepisyo at kaligtasan [4]. Kaugnay ng operasyon, maaaring maging bahagi ang CBD ng isang pinagsamang plano para sa pain relief pagkatapos ng keyhole rotator cuff repair nang hindi nakasasama sa iyong paggaling sa maikli o mahabang panahon [12, 13]. Ngunit ang parehong substansya ay maaaring mukhang walang panganib sa isang sitwasyon at may problema sa iba, kaya nakadepende ang ebidensya sa iyong partikular na kondisyon o operasyon. Ang pinakamahalagang paalala: sabihin sa iyong doktor kung gumagamit ka ng cannabis o CBD, para matimbang nila kung ano ang sinasabi ng pananaliksik para sa iyong sitwasyon, at kung ano ang hindi pa nito sinasabi.

Mga Sanggunian

[1] Hand Surgery Patient Perspectives on Medical Cannabis: A Survey of Over 600 Patients. Journal of Hand Surgery Global Online. 2023. DOI: 10.1016/j.jhsg.2022.02.009

[2] Perceptions in orthopedic surgery on the use of cannabis in treating pain: a survey of patients with spine pain (POSIT Spine). Journal of Orthopaedic Surgery and Research. 2024. DOI: 10.1186/s13018-024-04558-6

[3] Assessment of Medical Cannabis in Patients With Osteoarthritis of the Thumb Basal Joint. The Journal of Hand Surgery. 2023. DOI: 10.1016/j.jhsa.2021.10.018

[4] Medical Cannabis in Hand Surgery: A Review of the Current Evidence. The Journal of Hand Surgery. 2023. DOI: 10.1016/j.jhsa.2022.11.008

[5] CORR Insights®: Does Cannabis-based Medicine Improve Pain and Sleep Quality in Patients With Traumatic Brachial Plexus Injuries? A Triple-blind, Crossover, Randomized Controlled Trial. Clinical Orthopaedics & Related Research. 2024. DOI: 10.1097/corr.0000000000003265

[6] A Synthetic Form of Cannabinoid Does Not Decrease Opioid Use After Total Knee Arthroplasty: A Prospective, Randomized, Triple-Blind, Placebo-Controlled Study. The Journal of Arthroplasty. 2026. DOI: 10.1016/j.arth.2026.02.047

[7] CORR Insights®: Do Medical and Recreational Marijuana State Laws Impact Trends in Postoperative Opioid Prescriptions Among Patients Who Have Undergone TJA?. Clinical Orthopaedics & Related Research. 2025. DOI: 10.1097/corr.0000000000003472

[8] Is Cannabis Dependence Associated with Postoperative Infections in Hand and Wrist Surgeries?. Journal of Hand Surgery Global Online. 2026. DOI: 10.1016/j.jhsg.2026.100948

[9] Knowledge and Opinion on Cannabinoids Among Orthopaedic Traumatologists. JAAOS: Global Research and Reviews. 2021. DOI: 10.5435/jaaosglobal-d-21-00047

[10] Cannabis Use Does Not Affect Outcomes After Total Hip Arthroplasty. The Journal of Arthroplasty. 2023. DOI: 10.1016/j.arth.2023.03.040

[11] The Use of Cannabinoids in the Treatment of Peripheral Neuropathy and Neuropathic Pain: A Systematic Review. The Journal of Hand Surgery. 2025. DOI: 10.1016/j.jhsa.2024.09.015

[12] Cannabidiol for Postoperative Pain Control After Arthroscopic Rotator Cuff Repair Demonstrates No Deficits in Patient-Reported Outcomes Versus Placebo: 1-Year Follow-up of a Randomized Controlled Trial. Orthopaedic Journal of Sports Medicine. 2024. DOI: 10.1177/23259671231222265

[13] Poster 186: Cannabidiol for Post-Operative Pain Control after Arthroscopic Rotator Cuff Repair Demonstrates No Functional Deficits at 1-Year. Orthopaedic Journal of Sports Medicine. 2023. DOI: 10.1177/2325967123s00172

[14] No Evidence That Preoperative Marijuana Use Influences the Success of Hip Arthroscopy for Femoracetabular Impingement in Adolescents and Young Adults. Orthopaedic Journal of Sports Medicine. 2025. DOI: 10.1177/23259671251385152

[15] Effect of Marijuana Use on Pain Management and Return to Sport After Anterior Cruciate Ligament Reconstruction in Pediatric and Adolescent Patients: A Matched Control Study. Orthopaedic Journal of Sports Medicine. 2025. DOI: 10.1177/23259671251369015

[16] Poster 189. Cannabis Use in Patients Undergoing Sports Medicine Procedures and Post-Operative Pain Scores. Orthopaedic Journal of Sports Medicine. 2026. DOI: 10.1177/2325967126s00487

[17] Effects Of Cannabidiol On Post-Operative Pain Following Arthroscopic Rotator Cuff Repair. Journal of Shoulder and Elbow Surgery. 2023. DOI: 10.1016/j.jse.2023.02.032

[18] Cannabis and nicotine use are independently associated with adverse surgical, medical, and psychosocial outcomes following upper extremity fracture fixation. Journal of Orthopaedic Surgery and Research. 2026. DOI: 10.1186/s13018-025-06635-w

Reviewed by Kieran Hirpara · 13 June 2026.

Want the clinical detail? Read the clinician version.

Talk to your treating clinician for advice specific to you.

For an appointment with the CQ Hand + Upper Limb team, ask your GP about a referral or visit www.cqupperlimb.com.

Evidence & references

This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.

Overview

  • Cannabidiol (CBD) can be considered in a postoperative multimodal pain management regimen without detrimental effects on patient-reported outcomes at 1-year follow-up after arthroscopic rotator cuff repair [1].
  • CBD can be considered in a postoperative multimodal pain management regimen without long-term functional deficits at 1-year follow-up after arthroscopic rotator cuff repair [2].
  • Cannabis-based medicines are applicable for the treatment of peripheral neuropathy and neuropathic pain [3].
  • 89% of participants in a survey of musculoskeletal pain patients considered medical cannabis to be more effective than narcotics for adequate pain management [4].
  • Regular cannabis use may be associated with increased opioid usage in the context of total joint arthroplasty [5].
  • No specific guidance for the use of cannabis in perioperative pain management can be suggested based on the association between regular cannabis use and increased opioid usage after total joint arthroplasty [5].
  • Patients estimated that medical cannabis could treat more than half of their spine pain [6].
  • One in three patients with spine pain were already using medical cannabis [6].
  • 79% of patients with spine pain believe cannabis could reduce opioid usage [6].
  • Most survey respondents in the orthopaedic sports medicine community believed that CBD has a role in postoperative and chronic pain management [7].
  • Large numbers of patients with osteoarthritis of the thumb basal joint would be interested in trialing either oral or topical formulations of medical cannabis for treatment of their pain [8].
  • 80.9% of patients presenting for hand and upper-extremity complaints would consider using medical cannabis [9].
  • Patients presenting for hand and upper-extremity complaints perceive medical cannabis as a safe treatment option for common orthopedic conditions [9].
  • Cost is identified as a major barrier to the use of medical cannabis by patients presenting for hand and upper-extremity complaints [9].
  • A synthetic form of THC does not appear to limit opioid intake after primary total knee arthroplasty [10].
  • Current evidence demonstrates efficacy and safety for chronic musculoskeletal and neuropathic pain [19].
  • Definitive conclusions regarding the efficacy of medical cannabis in hand and upper extremity conditions require continued investigation [19].

How It Works

  • Cannabidiol (CBD) can be considered in a postoperative multimodal pain management regimen without long-term functional deficits at 1-year follow-up after arthroscopic rotator cuff repair [2].
  • 89% of participants considered medical cannabis to be more effective than narcotics for adequate pain management [4].
  • No specific guidance in the use of cannabis in perioperative pain management can be suggested based on the association between regular cannabis use and increased opioid usage after total joint arthroplasty [5].
  • Cannabis-based medicine did not provide clinical improvement in pain compared with a placebo in patients with traumatic brachial plexus injuries [11].
  • A majority of sports medicine surgeons believe that CBD has a role in post-operative and chronic pain management [12].
  • More clinical research for cannabinoids is needed to help orthopaedic traumatologists provide guidance for patients seeking advice for this therapeutic [13].
  • Patients with documented cannabis dependence demonstrated higher odds of developing wound complications following hand and wrist soft-tissue surgical procedures [16].

What the Evidence Shows

Postoperative Pain Management

  • CBD can be considered in a post-operative multimodal pain management regimen without long-term functional deficits at 1-year follow-up after arthroscopic rotator cuff repair [2].
  • Buccally absorbed CBD demonstrates an acceptable safety profile and shows significant promise in reducing pain in the immediate peri-operative period following arthroscopic rotator cuff repair compared to control [17].
  • Cannabis use does not affect outcomes after total hip arthroplasty [14].
  • Further studies are warranted to determine the efficacy and safety of perioperative cannabis use after total hip arthroplasty to help guide orthopaedic surgeons in counseling patients [14].
  • Higher-level studies are needed to ascertain the impact of cannabis use for patients undergoing total joint arthroplasty [15].

Neuropathic Pain

  • Cannabis-based treatment did not provide clinically important benefit as an adjuvant to standard multimodal drug therapy for neuropathic pain in traumatic brachial plexus injuries [18].
  • Findings suggest the applicability of cannabis-based medicines for peripheral neuropathy [3].

Patient and Surgeon Perceptions

  • Patients estimated medical cannabis could treat more than half of their spine pain [6].

Practical Considerations

Postoperative Pain Management

  • CBD can be considered in a postoperative multimodal pain management regimen without detrimental effects on outcome [1].
  • CBD can be considered in a post-operative multimodal pain management regimen without long-term detrimental effects [2].

Patient and Provider Perceptions

  • Large numbers of patients with osteoarthritis of the thumb basal joint would be interested in trialing either oral or topical formulations of medical cannabis for treatment of their thumb basal joint pain [8].

Clinical Guidance and Research Needs

  • No specific guidance in the use of cannabis in perioperative pain management can be suggested based on the association between regular cannabis use and increased opioid usage in total joint arthroplasty [5].
  • More clinical research for cannabinoids is needed to help orthopaedic traumatologists provide guidance for patients seeking advice [13].

Key Evidence

  • [L2] These findings suggest that CBD can be considered in a postoperative multimodal pain management regimen without detrimental effects on outcome. [1] (10.1177/23259671231222265)
  • [L2] These findings suggest that CBD can be considered in a post-operative multimodal pain management regimen without long-term detrimental effects. [2] (10.1177/2325967123s00172)
  • [L2] These findings suggest the applicability of cannabis-based medicines for peripheral neuropathy. [3] (10.1016/j.jhsa.2024.09.015)
  • [L4] In addition, 89% of the participants considered medical cannabis to be more effective than narcotics for adequate pain management. [4] (10.5435/jaaosglobal-d-22-00055)
  • [Paper] Regular cannabis use may be associated with increased opioid usage in the context of total joint arthroplasty, and no specific guidance in the use of cannabis in perioperative pain management can be suggested based on this discovery. [5] (10.1097/corr.0000000000003472)
  • [L4] Patients estimated medical cannabis could treat more than half of their spine pain, with one in three patients already using medical cannabis, and 79% of patients believe cannabis could reduce opioid usage. [6] (10.1186/s13018-024-04558-6)
  • [L4] Most survey respondents believed that CBD has a role in postoperative and chronic pain management. [7] (10.1177/23259671231191766)
  • [L4] Large numbers of these patients would be interested in trialing either oral or topical formulations of medical cannabis for treatment of their thumb basal joint pain. [8] (10.1016/j.jhsa.2021.10.018)
  • [L3] Most patients presenting for hand and upper-extremity complaints would consider using medical cannabis (80.9%) and perceive it as a safe treatment option for common orthopedic conditions, with cost identified as a major barrier to use. [9] (10.1016/j.jhsg.2022.02.009)
  • [L1] Despite enthusiasm for cannabis after orthopaedic surgical procedures, this THC does not appear to limit opioid intake after primary TKA. [10] (10.1016/j.arth.2026.02.047)
  • [L1] Cannabis-based medicine did not provide clinical improvement in pain compared with a placebo in patients with traumatic brachial plexus injuries. [11] (10.1097/corr.0000000000003221)
  • [L4] A majority of sports medicine surgeons believe that CBD has a role in post-operative and chronic pain management. [12] (10.1177/2325967123s00336)
  • [L4] More clinical research for cannabinoids is needed to help orthopaedic traumatologists provide guidance for patients seeking advice for this recently popular therapeutic. [13] (10.5435/jaaosglobal-d-21-00047)
  • [L3] Further studies are warranted to determine the efficacy and safety of perioperative cannabis use after THA to help guide orthopaedic surgeons in counseling patients. [14] (10.1016/j.arth.2023.03.040)
  • [L1] Higher-level studies are needed to ascertain the impact of cannabis use for patients undergoing TJA. [15] (10.1016/j.arth.2023.07.008)
  • [L2] Patients with documented cannabis dependence demonstrated higher odds of developing wound complications following hand and wrist soft-tissue surgical procedures. [16] (10.1016/j.jhsg.2026.100948)
  • [L1] Buccally absorbed CBD demonstrates an acceptable safety profile and shows significant promise in reduction of pain in the immediate peri-operative period following ARCR compared to the control. [17] (10.1016/j.jse.2023.02.032)
  • [Paper] This is a commentary on a randomized controlled trial by Kittithamvongs et al., which found no clinically important benefit to cannabis-based treatment as an adjuvant to standard multimodal drug therapy for neuropathic pain in traumatic brachial plexus injuries. [18] (10.1097/corr.0000000000003265)
  • [L4] Current evidence demonstrates efficacy and safety for chronic musculoskeletal and neuropathic pain, but definitive conclusions regarding efficacy in hand and upper extremity conditions require continued investigation. [19] (10.1016/j.jhsa.2022.11.008)

References

[1] Cannabidiol for Postoperative Pain Control After Arthroscopic Rotator Cuff Repair Demonstrates No Deficits in Patient-Reported Outcomes Versus Placebo: 1-Year Follow-up of a Randomized Controlled Trial. Orthopaedic Journal of Sports Medicine. 2024. DOI: 10.1177/23259671231222265

[2] Poster 186: Cannabidiol for Post-Operative Pain Control after Arthroscopic Rotator Cuff Repair Demonstrates No Functional Deficits at 1-Year. Orthopaedic Journal of Sports Medicine. 2023. DOI: 10.1177/2325967123s00172

[3] The Use of Cannabinoids in the Treatment of Peripheral Neuropathy and Neuropathic Pain: A Systematic Review. The Journal of Hand Surgery. 2025. DOI: 10.1016/j.jhsa.2024.09.015

[4] Patient Experience and Perspective on Medical Cannabis as an Alternative for Musculoskeletal Pain Management. JAAOS: Global Research and Reviews. 2022. DOI: 10.5435/jaaosglobal-d-22-00055

[5] CORR Insights®: Do Medical and Recreational Marijuana State Laws Impact Trends in Postoperative Opioid Prescriptions Among Patients Who Have Undergone TJA?. Clinical Orthopaedics & Related Research. 2025. DOI: 10.1097/corr.0000000000003472

[6] Perceptions in orthopedic surgery on the use of cannabis in treating pain: a survey of patients with spine pain (POSIT Spine). Journal of Orthopaedic Surgery and Research. 2024. DOI: 10.1186/s13018-024-04558-6

[7] Perceptions and Opinions on Cannabidiol in the Orthopaedic Sports Medicine Community. Orthopaedic Journal of Sports Medicine. 2023. DOI: 10.1177/23259671231191766

[8] Assessment of Medical Cannabis in Patients With Osteoarthritis of the Thumb Basal Joint. The Journal of Hand Surgery. 2023. DOI: 10.1016/j.jhsa.2021.10.018

[9] Hand Surgery Patient Perspectives on Medical Cannabis: A Survey of Over 600 Patients. Journal of Hand Surgery Global Online. 2023. DOI: 10.1016/j.jhsg.2022.02.009

[10] A Synthetic Form of Cannabinoid Does Not Decrease Opioid Use After Total Knee Arthroplasty: A Prospective, Randomized, Triple-Blind, Placebo-Controlled Study. The Journal of Arthroplasty. 2026. DOI: 10.1016/j.arth.2026.02.047

[11] Does Cannabis-based Medicine Improve Pain and Sleep Quality in Patients With Traumatic Brachial Plexus Injuries? A Triple-blind, Crossover, Randomized Controlled Trial. Clinical Orthopaedics & Related Research. 2024. DOI: 10.1097/corr.0000000000003221

[12] Poster 373: Perceptions & Opinions on Cannabidiol Among Sports Medicine Orthopaedic Surgeons. Orthopaedic Journal of Sports Medicine. 2023. DOI: 10.1177/2325967123s00336

[13] Knowledge and Opinion on Cannabinoids Among Orthopaedic Traumatologists. JAAOS: Global Research and Reviews. 2021. DOI: 10.5435/jaaosglobal-d-21-00047

[14] Cannabis Use Does Not Affect Outcomes After Total Hip Arthroplasty. The Journal of Arthroplasty. 2023. DOI: 10.1016/j.arth.2023.03.040

[15] Cannabis Use Following Total Joint Arthroplasty is Associated With Increased Risks? A Meta-Analysis. The Journal of Arthroplasty. 2024. DOI: 10.1016/j.arth.2023.07.008

[16] Is Cannabis Dependence Associated with Postoperative Infections in Hand and Wrist Surgeries?. Journal of Hand Surgery Global Online. 2026. DOI: 10.1016/j.jhsg.2026.100948

[17] Effects Of Cannabidiol On Post-Operative Pain Following Arthroscopic Rotator Cuff Repair. Journal of Shoulder and Elbow Surgery. 2023. DOI: 10.1016/j.jse.2023.02.032

[18] CORR Insights®: Does Cannabis-based Medicine Improve Pain and Sleep Quality in Patients With Traumatic Brachial Plexus Injuries? A Triple-blind, Crossover, Randomized Controlled Trial. Clinical Orthopaedics & Related Research. 2024. DOI: 10.1097/corr.0000000000003265

[19] Medical Cannabis in Hand Surgery: A Review of the Current Evidence. The Journal of Hand Surgery. 2023. DOI: 10.1016/j.jhsa.2022.11.008

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