Patients › Wrist
Quistes ganglionares de la muñeca
Wrist ganglia are common, fluid-filled lumps – often painless – and this page covers observation, aspiration, and excision.
Qué está sintiendo¶
Un quiste ganglionar de muñeca es un bulto lleno de líquido que se forma a partir de la articulación o de un tendón de la muñeca. Normalmente se percibe como un bulto liso en la parte dorsal de la muñeca, justo encima del centro de la articulación. Algunos quistes, en cambio, se localizan en la cara palmar, cerca del pliegue anterior de la muñeca. El tamaño del bulto puede variar; suele ser firme al tacto y permanece en el mismo lugar.
El bulto suele ser lo primero que se nota, pero también es frecuente sentir molestias o dolor. El dolor suele localizarse exactamente en el sitio del bulto y a veces se extiende un poco a toda la muñeca. Con frecuencia empeora tras realizar actividades, especialmente aquellas que implican flexionar la muñeca contra resistencia, como levantarse de una silla empujando con las manos, cargar bolsas de la compra o apoyarse en la mano para incorporarse del suelo. El reposo y el uso de una férula pueden aliviarlo. Algunas personas notan más dolor por la noche o al despertar.
Las tareas cotidianas que requieren una muñeca fuerte y estable pueden volverse incómodas: presionar con la palma, retorcer un paño, levantar una tetera pesada o sujetar una herramienta pueden empeorar los síntomas. En algunos casos, el quiste ejerce presión sobre estructuras cercanas, provocando chasquidos, sensación de “traba” o disminución de la fuerza de agarre.
Hay algunos datos importantes que conviene conocer. La mayoría de los quistes en la parte dorsal de la muñeca disminuyen o desaparecen por sí solos con el tiempo; aproximadamente el 40 % se reducen durante los primeros 6 años. En niños menores de 10 años, la mayoría de los quistes en la cara palmar desaparecen solos en un plazo de 12 a 18 meses. Algunos quistes parecen pequeños en la superficie, pero se extienden más profundamente dentro de la muñeca de lo que se aprecia a simple vista; por eso los examinamos cuidadosamente antes de recomendar cualquier tratamiento.
Si el bulto no duele y no le causa molestias, observarlo y esperar puede ser una opción razonable. En cambio, si le provoca dolor, limita el uso de la mano o le impide dormir, entonces merece la pena considerar un tratamiento.
¿Qué está ocurriendo realmente?¶
Un ganglio es un saco relleno de un líquido espeso y gelatinoso. Se forma a partir del revestimiento de una articulación de la muñeca o de la vaina tendinosa cercana. Imagine el revestimiento articular como una especie de junta blanda que sella y amortigua la articulación. Cuando esa junta se debilita, el líquido puede filtrarse y formar una protuberancia bajo la piel, similar a una pequeña ampolla de agua en una manguera de jardín.
La protuberancia en sí no lo explica todo. Por lo general, permanece conectada a la articulación mediante un tallo estrecho, parecido a una pajita. El líquido circula a través de ese tallo entre la articulación y la protuberancia; por eso esta puede aumentar o disminuir de tamaño. En el dorso de la muñeca, el tallo casi siempre conduce a un ligamento pequeño situado en el centro de la articulación. En la cara palmar, suele conectarse a una articulación cercana a la base del pulgar.
Esa conexión explica sus síntomas. Cuando dobla la muñeca hacia atrás bajo carga, el líquido se ve forzado a través del tallo y la protuberancia se tensa; por eso el dolor aumenta tras la actividad física. Además, la protuberancia puede situarse cerca de nervios o vasos sanguíneos en la cara palmar, lo que también contribuye a la molestia.
En ocasiones, el propio ligamento cercano al tallo se irrita o sufre una distensión leve. Esto puede provocar un dolor profundo incluso cuando la protuberancia es pequeña. Es importante saber que una protuberancia en el dorso de la muñeca a veces está relacionada con una pequeña brecha o debilidad en dicho ligamento; por eso evaluamos toda la muñeca, no solo la protuberancia.
Existen otras condiciones que pueden parecerse a esto. Por ejemplo, una protuberancia ósea dura en la base del pulgar o del nudillo del dedo índice. También puede tratarse de un engrosamiento a lo largo de un tendón en el dorso de la muñeca. Estas afecciones se tratan de manera distinta, por lo que confirmamos primero de qué se trata exactamente su protuberancia antes de recomendar cualquier tratamiento.
Qué podemos hacer al respecto¶
El Dr. Kieran Hirpara, cirujano de extremidades superiores en el Mater Private Hospital Rockhampton, comienza con las opciones menos invasivas que se adapten a su condición. Por lo general, los pacientes son derivados a nuestra clínica por su médico de cabecera; si un fisioterapeuta le ha sugerido consultarnos, igualmente necesitará una derivación de su médico de cabecera para poder acceder al reembolso de Medicare. En su primera visita, tomamos su historia clínica, examinamos su muñeca y solicitamos estudios de imagen únicamente si esto cambiará nuestras recomendaciones. Muchos bultos en la muñeca no requieren estudios de imagen en absoluto.
Dado que estos bultos a menudo desaparecen por sí solos, normalmente empezamos con una observación y espera. El reposo, evitar los movimientos que agravan el dolor y el uso de una férula para la muñeca pueden ayudar a aliviar los síntomas. La terapia de la mano busca calmar el dolor y mantener la movilidad de la muñeca mientras el bulto disminuye de tamaño o permanece igual. Algunos bultos se reducen lentamente a lo largo de los años, por lo que solemos recomendar probar estas medidas sencillas antes de recurrir a tratamientos más activos.
Si el bulto resulta doloroso, una opción es drenarlo con una aguja. El líquido es espeso y gelatinoso, por lo que el bulto puede reaparecer después. El drenaje del bulto, con o sin inyección de cortisona en sus alrededores, tiene éxito en entre el 35% y el 50% de los casos. Discutimos esta opción con usted y la evaluamos juntos.
La cirugía se considera cuando el dolor no cede, cuando el bulto reaparece tras el drenaje o cuando ejerce presión sobre alguna estructura de la muñeca. La operación consiste en extirpar el bulto y el pequeño tallo que lo conecta con la articulación, de donde proviene el líquido. Algunos bultos pueden tratarse mediante cirugía laparoscópica, usando una cámara diminuta dentro de la articulación; otros requieren una pequeña incisión abierta. Existe una página específica sobre la cirugía, y le explicaremos cuál método se adapta mejor a su caso.
La cirugía elimina el bulto de manera más fiable que el drenaje, aunque no es infalible: en alrededor del 10% de los casos el bulto reaparece tras la operación. Como ocurre con cualquier intervención quirúrgica en la muñeca, existen riesgos como infección, lesión de nervios pequeños y rigidez. Analizaremos todo esto con usted antes de tomar cualquier decisión; la elección siempre será suya.
Qué esperar¶
El pronóstico depende en gran medida del tratamiento que elija. Si deja el bulto sin tratar, hay una buena posibilidad de que desaparezca por sí solo. Muchos bultos se reducen o desaparecen con el tiempo; los niños menores de 10 años con un bulto en la cara palmar de la mano responden especialmente bien sin ningún tratamiento. Observar el bulto y esperar no le costará nada, salvo paciencia; algunos bultos tardan años en desaparecer.
Drenar el bulto con una aguja es un procedimiento rápido, pero el líquido suele volver a acumularse. Por eso, normalmente lo consideramos un paso dentro de un plan terapéutico más amplio, no una cura definitiva. Si el bulto sigue reapareciendo tras el drenaje, la cirugía se convierte en la opción más duradera.
La cirugía ofrece el resultado más fiable. La mayoría de los pacientes quedan satisfechos con el resultado una vez que la muñeca se ha estabilizado.
La recuperación tras la cirugía suele ser sencilla. Al principio, la muñeca le dolerá y estará algo rígida; se recomienda realizar movimientos suaves desde el inicio, a menudo dentro de las primeras 2 semanas. Mantener la muñeca en movimiento desde el principio reduce el riesgo de rigidez persistente. La rigidez es menos frecuente tras una cirugía en la cara palmar que en la cara dorsal de la muñeca, aunque puede ocurrir si no se mantiene el movimiento.
Hay algunos aspectos que conviene conocer antes de tomar una decisión. Algunas personas experimentan un dolor leve en la muñeca después de la cirugía; esto es más probable si su trabajo o actividades requieren doblar la muñeca con fuerza. Las mujeres que ya sentían dolor antes de la cirugía también tienen más probabilidades de seguir sintiendo molestias después. La cicatriz puede ser visible, y en ocasiones los pequeños nervios cercanos al bulto pueden irritarse. Analizaremos todo esto con usted antes de que tome cualquier decisión.
Si el bulto no le causa molestias, dejarlo sin tratar es una opción totalmente razonable. Si le duele, limita el uso de la mano o sigue reapareciendo tras el drenaje, la cirugía ofrece una solución duradera para la mayoría de las personas.
¿Cuándo consultar a un especialista?¶
La mayoría de los bultos en la muñeca no requieren atención urgente, y muchos desaparecen por sí solos. Consulte a su médico de cabecera para que lo derive a un especialista si el bulto le duele, limita el movimiento de su mano o reaparece después de haber sido drenado. Acuda a revisión más pronto si el bulto crece rápidamente, se siente duro y fijo en lugar de ser lleno de líquido, o si se encuentra cerca de un nervio y provoca hormigueo, entumecimiento o debilidad en los dedos. Un bulto que ejerce presión sobre un nervio puede causar irritación duradera; por eso es conveniente tratarlo a tiempo. Acuda a urgencias si nota un cambio repentino de color, frío o pérdida del pulso en la mano, ya que esto podría indicar un problema vascular. Si en un niño el bulto no desaparece tras unos 2 meses de observación y uso de férula, o si vuelve a aparecer, solicite una evaluación especializada.
En mayor profundidad¶
Esta sección profundiza más de lo necesario para que usted tome sus propias decisiones terapéuticas. Los quistes ganglionares de la muñeca merecen una lectura más detallada, pues en realidad la elección radica entre aceptar el riesgo de recurrencia o someterse a una intervención quirúrgica; además, las cifras que sustentan esta decisión son lo suficientemente claras como para tomar una determinación.
La aspiración vuelve a producirse; la excisión, en cambio, no, con frecuencia¶
Los dos tratamientos activos son extraer el quiste mediante una aguja y extirparlo quirúrgicamente junto con su tallo. Tras analizar 2,239 pacientes, se observa que la excisión quirúrgica abierta presenta una probabilidad significativamente menor de recurrencia que la aspiración. La excisión artroscópica ha arrojado resultados prometedores, pero los datos de ensayos comparativos son limitados y no han demostrado su superioridad [1].
Este mecanismo explica dicha diferencia. Un quiste ganglionar no es un saco de líquido flotante libremente; está conectado mediante un tallo a la cápsula articular subyacente, y la articulación sigue produciendo líquido. La aspiración vacía el reservorio pero deja intacta su fuente de origen; por ello, el rellenado del quiste es un resultado frecuente en lugar de un fracaso terapéutico. La excisión, en cambio, busca localizar y extirpar el tallo en su punto de origen.
La extirpación mediante técnica mínimamente invasiva y la abierta arrojan resultados similares¶
Cuando se opta por la extirpación, se han comparado directamente ambos métodos. En un total de 910 pacientes, los resultados en cuanto a recurrencia y complicaciones fueron comparables entre la técnica artroscópica y la abierta. Los autores abogan por la realización de estudios estandarizados y con suficiente potencia estadística [2].
Por ello, la decisión entre ambos métodos debe basarse en criterios secundarios: la presencia de cicatrices, la familiaridad del cirujano con cada técnica, y si es necesario examinar otras patologías intraarticulares simultáneamente, más que en el riesgo de recurrencia.
Nadie se pone de acuerdo sobre qué hacer después, y quizás eso no importe¶
Un hallazgo sencillo y honesto: una revisión sistemática y una encuesta realizadas entre cirujanos de mano revelaron que existe división de opiniones respecto a si se debe inmovilizar la muñeca tras la extirpación de un ganglio dorsal; además, en cuanto a los resultados funcionales, no existen datos concluyentes que indiquen que alguna estrategia sea superior [3].
Vale la pena saber que las diferencias en las indicaciones dadas por los cirujanos reflejan realmente una incertidumbre clínica, y no que alguno de ellos esté equivocado.
El argumento más contundente suele ser no hacer nada¶
Ninguno de los puntos anteriores demuestra que un ganglio deba ser tratado. Se trata de quistes benignos que con frecuencia varían en tamaño; además, una parte de ellos desaparece sin necesidad de intervención alguna. No evolucionan hacia ninguna otra patología.
Esto cambia por completo la perspectiva de la decisión terapéutica. Las razones para tratarlo son el dolor, la interferencia con el movimiento de la muñeca o la capacidad de agarre, la presión sobre algún nervio cercano, o un tamaño que realmente moleste al paciente; no la mera presencia del bulto. Teniendo en cuenta que la aspiración conlleva una tasa significativa de recurrencia y que la extirpación implica los riesgos propios de una intervención quirúrgica en la cápsula articular, la observación cuidadosa constituye una opción válida como primera medida, y merece ser mencionada explícitamente en lugar de considerarse una falta de acción.
La excepción se da cuando el ganglio provoca síntomas neurológicos: entumecimiento, debilidad o dolor que se irradia a la mano. En esos casos, el quiste comprime una estructura que no puede tolerar dicha presión indefinidamente; por lo tanto, la observación cuidadosa deja de ser la opción de menor riesgo.
Referencias¶
[1] Head L, Gencarelli JR, Allen M, Boyd KU. Tratamiento de los quistes ganglionares de la muñeca: revisión sistemática y metaanálisis. J Hand Surg Am. 2015;40(3):546-553.e8. https://doi.org/10.1016/j.jhsa.2014.12.014
[2] Crawford C, Keswani A, Lovy AJ, Levy I, Lutz K, Kim J, et al. Excisión artroscópica versus abierta de los quistes ganglionares dorsales: revisión sistemática y metaanálisis. J Hand Surg Eur Vol. 2017;43(6):659-64. https://doi.org/10.1177/1753193417734428
[3] Wong CR, Karpinski M, Hatchell AC, McRae MH, Murphy J, McRae MC. Inmovilización de la muñeca tras la excisión de quistes ganglionares dorsales: revisión sistemática y encuesta. Hand (N Y). 2021;18(2):254-63. https://doi.org/10.1177/15589447211014631
Evidence & references
This is the clinical evidence summary written for health professionals. It is technical, and it lists the research this page was built from. You do not need to read it to understand your treatment or to make a decision about it.
Overview¶
Epidemiology and Natural History¶
- The dorsal wrist ganglion is the prototype of all hand and wrist ganglions, accounting for 60% to 70% of all hand and wrist ganglions [1].
- The volar wrist ganglion is the second most common ganglion of the hand and wrist, accounting for 18% to 20% of cases [7].
- Pediatric ganglions of the hand have a greater rate of resolution than ganglions of the wrist [2].
- Observation and/or splinting will likely be helpful in the resolution of a majority of pediatric hand and wrist ganglions [17].
- There is no consensus within the literature regarding the best management of pediatric wrist ganglia, and no single treatment modality confers a particular advantage or disadvantage over another [11].
Clinical Characteristics and Diagnosis¶
- The main cyst of a dorsal wrist ganglion is usually located directly over the scapholunate ligament [1].
- Dorsal wrist ganglions may occur anywhere else between the extensor tendons and can be connected to the scapholunate ligament through an elongated pedicle [1].
- Careful preoperative palpation of a dorsal wrist ganglion with digital compression often reveals its extent and the direction of the pedicle [1].
- Transillumination or aspiration confirms the diagnosis of a dorsal wrist ganglion preoperatively [1].
- Review of preoperative radiographs is recommended to rule out an interosseous component in dorsal wrist ganglions [1].
- The majority of volar wrist ganglions occur either directly over the distal edge of the radius or slightly more distally over the scaphoid tubercle [7].
- Volar wrist ganglions arising from the radiocarpal joint occur under the volar wrist crease between the flexor carpi radialis and abductor pollicis longus tendons [7].
- The main cyst of a volar wrist ganglion may be intertwined with bifurcating branches of the radial artery [7].
- Volar wrist ganglions may appear small clinically but can be surprisingly extensive at surgery, with multiloculated cysts extending under the thenar muscles, along the flexor carpi radialis tendon, into the carpal canal, and under the first extensor compartment [7].
- The Allen test should be performed routinely to assess the patency of the radial and ulnar arteries before volar wrist ganglion surgery [7].
- Routine wrist radiography is not cost-effective in the evaluation and treatment decision-making process for patients with a wrist ganglion due to a low prevalence of therapeutically significant findings [4].
Operative Treatment: Dorsal Wrist Ganglion¶
- Most dorsal wrist ganglions can be approached through a transverse incision over the proximal carpal row [1].
- A modified incision or second transverse incision may be necessary for dorsal ganglions not directly over the scapholunate ligament [1].
- The diagnosis of ganglion cyst should be made before commitment to a transverse incision because this type of incision is not readily incorporated into a limb-sparing incision in the event of a subsequent diagnosis of a malignant soft tissue tumor [1].
- Failure to identify and excise the pedicle attachment to the scapholunate ligament increases the likelihood of recurrence in dorsal wrist ganglions [1].
- The main cyst and its pedicle are mobilized down to the underlying joint capsule, which is opened along the border of the radius and scaphoid's proximal pole with the wrist in volar flexion [1].
- A small, mucin-filled duct is invariably seen piercing the transverse fibers of the scapholunate ligament, connecting the underlying scapholunate joint with the main cyst [1].
- The ganglion and its capsular attachments are tangentially excised off the scapholunate ligament [1].
- Arthroscopic resection of dorsal wrist ganglions is supported as a treatment option based on outcomes, recurrence, and complication rates over a minimum follow-up of 4 years [16].
- Arthroscopic ganglionectomy through an intrafocal cystic portal is a safe and efficacious option for the treatment of painful wrist ganglia [26].
- Routine midcarpal joint exploration during arthroscopic excision of dorsal wrist ganglions appeared to reduce recurrence at 1 year without negatively impacting patient outcomes [9].
- The ideal working portal for arthroscopic excision of a dorsal wrist ganglion is the 3-4 portal with visualization from the 4-5 or 6R portals [21].
Operative Treatment: Volar Wrist Ganglion¶
- The surgical technique for excision of a volar ganglion is similar to that for a dorsal ganglion, but exposure and precise identification of the capsular attachments are more difficult [7].
- Longitudinal incisions allow for optimal visualization during volar wrist ganglion excision [7].
- The radial artery is frequently intimately attached to the wall of a volar ganglion and may even be completely encircled by the ganglion [7].
- Loupe magnification aids in the dissection of the radial artery from a volar ganglion [7].
- The pedicle of a volar ganglion is traced to the volar joint capsule, usually the scaphotrapezial or radiocarpal ligament [7].
- The incision for volar wrist ganglion excision must be planned to allow for extension into the carpal tunnel or base of the thenar muscles [7].
- Arthroscopic resection of radiocarpal volar ganglia is a reasonable alternative to open excision with decreased postoperative morbidity, easy technique, and high rate of good results [31].
- Sonography-assisted arthroscopic resection is safer and more reliable for treating volar wrist ganglia [6].
- The best indication for arthroscopic volar wrist ganglionotomy is a sessile type of volar wrist ganglion arising from the radiocarpal joint and centered on the proximal wrist crease [10].
- Mobile ganglia with long pedicles are poor candidates for arthroscopic surgery of the volar wrist [10].
- Preoperative ultrasound scanning helps to confirm the articular origin and nature of a volar wrist ganglion cystic mass [10].
- An intraoperative arthrogram can identify the stalk of a volar ganglion arising from the radiocarpal joint, with absence of demonstrable contrast filling the stalk precluding the use of the arthroscopic technique [10].
- Ganglia arising from the midcarpal joint or scaphotrapezial (STT) joint will not be revealed by an arthrogram of the radiocarpal joint unless an interosseous ligament at the proximal carpal row is ruptured [10].
- The radioscaphocapitate and long radiolunate ligament interval may be the site of origin for the volar wrist ganglion [21].
Outcomes and Complications¶
- Surgical excision of primary wrist ganglia significantly reduces patient symptoms with low recurrence rates and high patient satisfaction [12].
- Open surgical excision offers a significantly lower chance of recurrence compared with aspiration in the treatment of wrist ganglions [32].
- Female patients who have preoperative pain around dorsal wrist ganglia were the most likely to have residual pain after surgery [3].
- Unexpected branches of the radial sensory or lateral antebrachial cutaneous nerves may be injured during volar wrist ganglion excision, leading to troublesome neuromas [7].
- Extensions of the routine incision into the carpal canal must avoid injury to the palmar cutaneous branch of the median nerve during volar wrist ganglion excision [7].
- Injuries to the radial artery during volar wrist ganglion excision can be repaired microscopically [7].
- Some authors recommend leaving a portion of the cyst wall attached to the radial artery to avoid arterial injury during volar wrist ganglion excision [7].
- Stiffness of the wrist is less common with volar ganglions than with dorsal ganglions, but it can occur if early motion is not encouraged [7].
- Curved incisions appear to consistently provide more attractive scars, especially near the volar wrist creases [7].
- Wrist arthroscopy is typically safe, with minor and transient complications [21].
- Nerve injury during wrist arthroscopy is related to portal placement or suture of the TFCC and typically affects the dorsal sensory branch of the radial or ulnar nerve [21].
- The superficial branch of the radial nerve averages 16 mm (5 to 22 mm) from the 3-4 portal [21].
- The dorsal sensory branch of the ulnar nerve averages 8 mm (0 to 14 mm) from the 6R portal [21].
- The 1-2 portal carries a high risk of injury to the superficial branch of the radial nerve [21].
- The 6U portal carries a high risk of injury to the dorsal sensory branch of the ulnar nerve [21].
Anatomy & Pathophysiology¶
Dorsal Wrist Ganglion¶
- The dorsal wrist ganglion accounts for 60% to 70% of all hand and wrist ganglions [1].
- Dorsal wrist ganglions may occur anywhere else between the extensor tendons, connected to the scapholunate ligament through an elongated pedicle [1].
- Failure to identify and excise the pedicle attachment to the scapholunate ligament increases the likelihood of recurrence [1].
- Dorsal wrist ganglions can be confused with carpal bosses, which are osteoarthritic spurs or prominences that develop at the base of the second or third carpometacarpal joints [18].
- A small ganglion is associated with a carpal boss in 30% of cases [18].
- Arthroscopic assessment found abnormalities in the scapholunate joint in 10 of 16 wrists with painful dorsal ganglia [78].
- In most cases of dorsal wrist ganglion, there is a mild chronic sprain of the scapholunate ligament which does not give rise to well-recognised radiological and clinical features associated with scapholunate instability [78].
Volar Wrist Ganglion¶
- The majority of volar ganglions occur either directly over the distal edge of the radius or slightly more distally over the scaphoid tubercle [7].
- Volar ganglions arising from the distal edge of the radius arise from the capsular and ligamentous fibers of the radiocarpal joint and occur under the volar wrist crease between the flexor carpi radialis and abductor pollicis longus tendons [7].
- Volar ganglions arising from the scaphoid tubercle arise from the capsule of the scaphotrapezial joint [7].
- The main cyst of a volar ganglion may be intertwined with bifurcating branches of the radial artery [7].
- Volar ganglions can be multiloculated, extending under the thenar muscles, along the flexor carpi radialis tendon, into the carpal canal, and under the first extensor compartment [7].
- Ganglia arising from the interval between the radioscapocapitate (RSC) and long radiolunate ligament (LRL) appear at the more lateral aspect of the distal radius on arthrogram [10].
- Ganglia arising from the interval between the long radiolunate ligament (LRL) and short radiolunate ligament (SRL) appear at a more central position of the distal radius on arthrogram [10].
- Ganglia arising from the midcarpal or scaphotrapezial (STT) joint will not be revealed by an arthrogram of the radiocarpal joint unless an interosseous ligament at the proximal carpal row is ruptured [10].
General Pathophysiology & Anatomy¶
- The articular (synovial) theory has gained worldwide acceptance as a scientifically proven explanation for the formation of ganglions [22].
- Intraneural ganglions of the hand and wrist are rare, with the ulnar nerve being the most commonly involved nerve in the upper extremity [22].
- The wrist is an anatomic region between the forearm and the hand, including the distal radioulnar, radiocarpal, and ulnocarpal joints and the eight carpal bones [37].
- The carpus comprises eight ossicles separated into a proximal row (scaphoid, lunate, triquetrum, pisiform) and a distal row (trapezium, trapezoid, capitate, hamate) [39].
- The scapholunate interosseous ligament is C-shaped in the sagittal plane, with the dorsal third being the thickest and strongest portion [39].
- The triangular fibrocartilage complex (TFCC) is formed by the central meniscus homolog, dorsal and volar radioulnar ligaments, the floor of the extensor carpi ulnaris tendon sheath, and volar ulnocarpal ligaments [39].
- The terminal branches of the radial, ulnar, and anterior interosseous arteries provide extraosseous blood supply to the carpus through three dorsal and three palmar transverse arterial arches [41].
- The dorsal radiocarpal ligament originates at the dorsal lip of the distal radius adjacent to Lister's tubercle and inserts into the lunate and triquetrum [39].
- The proximal carpal row has no muscular or tendinous attachments and functions as an intercalary segment [39].
Classification¶
Anatomical Location and Prevalence¶
- Dorsal wrist ganglions typically appear between the extensor pollicis longus and extensor digitorum communis tendons [1].
- In a cohort of 543 ganglions, 57% occurred over the dorsal aspect of the wrist [77].
- In a cohort of 543 ganglions, 17% occurred over the volar aspect of the wrist [77].
- In a cohort of 543 ganglions, 26% occurred on the fingers [77].
- In a cohort of 543 ganglions, 7% were mucous cysts [77].
- Ganglions in pediatric populations most commonly affect the dorsal wrist [14].
- In children aged <10 years, ganglions mainly occur on the volar wrist [8].
Demographics¶
- In a cohort of 543 ganglions, there were 363 females and 180 males, an almost 2 to 1 ratio [77].
- In a cohort of 543 ganglions, 80% of patients were between twenty and fifty years of age [77].
- Ganglions in pediatric populations demonstrate a female predilection [14].
- Most patients with intraneural ganglions are aged 30 to 50 years [22].
- The incidence of dorsal wrist ganglia was higher in the military compared with the civilian population [13].
Size and Duration¶
- In a cohort of 543 ganglions, 90% were less than two centimeters in diameter [77].
- In a cohort of 543 ganglions, 50% were between 0.5 and 2.0 centimeters in diameter [77].
- In a cohort of 543 ganglions, the majority had been present for less than two years [77].
- In a cohort of 543 ganglions, 150 had been present for less than three months [77].
- In a cohort of 543 ganglions, 99 had been present for more than five years [77].
Clinical Presentation¶
- Only one-fourth of patients in a cohort of 543 ganglions complained of pain when first seen [77].
- All patients in a cohort of 543 ganglions complained of a mass or lump in an extremity [77].
- Specific injury related to the onset of ganglion occurred in only fifty patients in a cohort of 543 [77].
- Most patients with intraneural ganglions present with a painless mass [22].
- Some patients with intraneural ganglions present with symptoms of nerve irritation or entrapment neuropathy [22].
Subtypes and Variants¶
- Intraneural ganglions of the hand and wrist are rare [22].
- The ulnar nerve is the most commonly involved nerve in intraneural ganglions of the upper extremity [22].
- The development of a trigger wrist is atypical, with multiple causes for its development [24].
Clinical Presentation¶
Dorsal Wrist Ganglion¶
- MRI scans provide relatively good reliability in establishing the diagnosis of an occult dorsal wrist ganglion, with a sensitivity of 83% when using intra-operative findings as the standard [15].
Volar Wrist Ganglion¶
- Volar ganglions arising from the radiocarpal joint occur under the volar wrist crease between the flexor carpi radialis and abductor pollicis longus tendons [7].
- Although volar ganglions may appear small clinically, they can be surprisingly extensive at surgery, potentially extending under the thenar muscles, along the flexor carpi radialis tendon, into the carpal canal, and under the first extensor compartment [7].
- Extensions of volar ganglions can often be appreciated preoperatively by careful palpation and digital compression [7].
- The Allen test should be performed routinely to assess the patency of the radial and ulnar arteries in patients with volar wrist ganglions [7].
Pediatric Ganglions¶
- In children aged <10 years, 69% to 79% of volar wrist ganglions display spontaneous regression within a span of 12-18 months [8].
- Ganglions in pediatric populations most commonly affect the dorsal wrist and demonstrate a female predilection [14].
- In a child with a wrist ganglion, if the cyst ultimately resolved, it usually did so within 18 months [29].
General Clinical Features and Diagnosis¶
- Most patients with intraneural ganglions are aged 30 to 50 years, though occurrence in children has also been reported [22].
- Most patients with intraneural ganglions present with a painless mass, while some may present with symptoms of nerve irritation or entrapment neuropathy [22].
- The ulnar nerve is the most commonly involved nerve in the upper extremity for intraneural ganglions [22].
- In patients with a clinical diagnosis of wrist ganglion cyst, the prevalence of a concordant pathological diagnosis is 98.6% [45].
- The prevalence of a discrepant pathological diagnosis in wrist ganglion specimens is 1.4%, and the prevalence of a discordant diagnosis is zero [45].
Investigations¶
Clinical Examination and Physical Diagnosis¶
- Careful preoperative palpation of a dorsal wrist ganglion with digital compression often reveals the extent of the cyst and the direction of the pedicle [1].
- A firm, bony, nonmobile, tender mass visible and palpable at the base of the carpometacarpal joints, especially when the wrist is flexed, is characteristic of a carpal boss [18].
- Sonography can localize occult ganglia [68].
Radiography¶
- Review of preoperative radiographs is wise to rule out an interosseous component in dorsal wrist ganglions [1].
- A carpal boss mass is best visualized radiologically with the hand in 30 to 40 degrees of supination and 20 to 30 degrees of ulnar deviation [18].
Magnetic Resonance Imaging (MRI)¶
- MRI is an excellent diagnostic modality to evaluate rapidly growing upper extremity masses and distinguish ganglions from malignant processes [54].
- Convolutional neural networks (CNNs) can detect ganglion cysts in wrist MRI [66].
- A lipoma or a ganglion can be clearly differentiated from dense tumors using CT scan, though it is difficult to be sure whether the tumor is benign or malignant [70].
Arthrography¶
- A wrist arthrogram can be performed immediately prior to arthroscopic intervention or as a separate investigative procedure for volar wrist ganglions [10].
- Intraoperative arthrogram of a ganglion arising from the radiocarpal joint involves injecting 3 to 5 cc of nonionic contrast solution admixed with 2% lidocaine into the radiocarpal joint at the 3-4 portal site under fluoroscopic guidance [10].
- Absence of demonstrable contrast filling the stalk with communication from the radiocarpal joint may preclude the use of arthroscopic volar wrist ganglionotomy [10].
- Ganglia arising from the interval between the RSC and LRL ligaments show up at the more lateral aspect of the distal radius on arthrogram, while those arising from the interval between the LRL and SRL ligaments show up at a more central position [10].
- Ganglia arising from the midcarpal joint or STT joint will not be revealed by arthrogram of the radiocarpal joint unless an interosseous ligament at the proximal carpal row is ruptured and creates free communication between the radiocarpal and midcarpal joints [10].
Treatment¶
Non-Operative Management¶
- The spontaneous resolution rate for wrist ganglia is reported to be between 28% and 58% [50].
- Aspiration, with or without cortisone injection, has an average success rate of 35% to 50% [50].
- In children aged <10 years, ganglions mainly occur on the volar wrist and can be treated expectantly, with 69% to 79% displaying spontaneous regression within a span of 12-18 months [8].
- Surgical excision is indicated for pediatric ganglions that are symptomatic, do not resolve after approximately 2 months of observation and/or splinting, or recur [17].
- Aspiration with triamcinolone acetonide injection plus wrist immobilization is an alternative method, but surgery was the most successful form of treatment when considering the cure rate of dorsal wrist ganglion [46].
- Open surgical excision offers significantly lower chance of recurrence compared with aspiration in the treatment of wrist ganglions [32].
- It is important to ascertain the precise concerns of patients with ganglia and not assume that they attend the hand clinic with symptoms which justify surgical excision [33].
Operative Management: Dorsal Wrist Ganglion¶
- Failure to identify the pedicle and excise its attachment to the scapholunate ligament increases the likelihood of recurrence [1].
- Careful preoperative palpation of the cyst with digital compression often reveals its extent and the direction of the pedicle [1].
- Transillumination or aspiration confirms the diagnosis preoperatively [1].
- Review of the patient's preoperative radiographs to rule out an interosseous component is wise [1].
- The study concludes that routinely performing wrist radiography is not cost-effective in the evaluation and treatment decision-making process for patients with a wrist ganglion due to a low prevalence of therapeutically significant findings [4].
- Most dorsal ganglions can be approached through a transverse incision over the proximal carpal row [1].
- A modified incision or second transverse incision may be necessary for ganglions not directly over the scapholunate ligament [1].
- Typically, a dorsal ganglion appears between the extensor pollicis longus and extensor digitorum communis tendons, which are retracted radially and ulnarly, respectively [1].
- The main cyst and its pedicle are mobilized down to the underlying joint capsule [1].
- With the wrist in volar flexion, the joint capsule is opened along the border of the radius and scaphoid's proximal pole [1].
- The capsule is elevated and retracted distally to expose the capsular attachments to the scapholunate ligament [1].
- Smaller intraarticular cysts are often seen attached to the scapholunate ligament [1].
- The capsular incision is continued around the ganglion, but all capsular attachments to the ligament are left intact [1].
- The capsular incision is extended more laterally if any capsular ducts, which can be identified by small amounts of mucin drainage, are encountered during the dissection [1].
- The ganglion and its capsular attachments are then tangentially excised off the scapholunate ligament [1].
- A small, mucin-filled duct is invariably seen piercing the transverse fibers of the scapholunate ligament [1].
- This duct appears to connect the underlying scapholunate joint with the main cyst [1].
- Synovial and capsular attachments along the distal margin of the scapholunate ligament are also excised to give an unobstructed view of the head and neck of the capitate [1].
- If the ganglion ruptures and its anatomic features are lost during the dissection, it should [1].
- The outcomes, recurrence, and complications rates after 4 years of follow-up presented in this study support the use of arthroscopy as a treatment for dorsal wrist ganglion [16].
- Nine of 54 (16.7%) arthroscopic excisions resulted in cyst recurrence, while 8 of 118 (6.8%) open excisions resulted in cyst recurrence (P = .044) [19].
- Two of 9 (22%) recurrences after arthroscopic ganglion excision versus 2 of 8 (25%) recurrences after open ganglion excision underwent repeat surgical intervention [19].
- Time to recurrence, as well as final follow-up, was not statistically different between groups in the comparison of arthroscopic and open excision [19].
- The proposed classification of ganglia helps minimize the area of resection required [25].
- Recurrence of the wrist ganglion cyst occurred in five patients (9%) in a cohort of 53 patients undergoing arthroscopic resection [58].
- PRWE scores were significantly higher in patients with a recurrence (30 vs. 12, p = 0.002) [58].
- Patients initially presenting with a new ganglion cyst had fewer recurrences at final follow-up compared with patients initially presenting with recurrence (4 vs. 15%, respectively) [58].
- Three of the 53 patients (6%) had a complication in the arthroscopic resection cohort [58].
- One patient experienced neuropraxia of the radial superficial nerve, which resolved spontaneously [58].
- One patient developed extensor carpi ulnaris (ECU) tendinitis which was successfully treated with splinting [58].
- One patient experienced painful scar tissue, which was successfully removed surgically [58].
- Three of the five recurrences occurred among the first five patients operated on, whereas two recurrences occurred later in the series [58].
- The systematic review and survey of Canadian hand surgeons reveal that hand surgeons are divided regarding the need to immobilize the wrist after dorsal wrist ganglion excision [60].
- Patients are seen in the office approximately 5 to 7 days after arthroscopic surgery, at which time the dressing and splint are taken down and the incisions are inspected [61].
- Sutures are typically removed at the first postoperative visit [61].
- Patients are then allowed to begin active and passive wrist motion, and no further splinting is used [61].
- The patients have no restrictions in terms of activity or weight lifting after arthroscopic ganglion excision [61].
- The patients are seen back at 4 to 8 weeks postoperatively for a repeat clinical evaluation [61].
- Recurrence rates following arthroscopic excision of dorsal ganglions have been reported from 0% to 17% [61].
- In a study of 18 patients undergoing arthroscopic excision of dorsal ganglions, the stalk could be identified in 61% of the cases, and the reported number of recurrences at an average of 16 months was 0 [61].
- In a study of 30 patients, the ability to identify the stalk was 79% of cases, and 2 of the patients had a recurrence at the final follow-up [61].
- Edwards and Johansen reported a 0% recurrence in their study of 45 patients and were able to identify the stalk in only 16% of the cases [61].
Operative Management: Volar Wrist Ganglion¶
- The volar wrist ganglion is the second most common ganglion of the hand and wrist, accounting for 18% to 20% [7].
- The main cyst may be intertwined with bifurcating branches of the radial artery, thus making delicate dissection imperative [7].
- Another type of volar ganglion arises from the capsule of the scaphotrapezial joint [7].
- Although volar ganglions may appear small clinically, they can be surprisingly extensive at surgery [7].
- Multiloculated cysts extending under the thenar muscles, along the flexor carpi radialis tendon, into the carpal canal, and under the first extensor compartment adjacent to the dorsal branch of the radial artery and as far dorsally as the first web space may be encountered [7].
- These extensions can often be appreciated preoperatively by careful palpation and digital compression of the ganglion [7].
- It is important to assess the patency of the radial and ulnar arteries [7].
- The Allen test should be performed routinely and ulnar artery occlusion excluded [7].
- The surgeon must be aware of the importance of preserving the radial artery, particularly in patients with a radial-dominant circulation [7].
- The surgical technique of excision of a volar ganglion is similar to that for a dorsal ganglion, but exposure and precise identification of the capsular attachments of a volar ganglion are more difficult [7].
- The incision must be planned to allow for extension into the carpal tunnel or base of the thenar muscles [7].
- Longitudinal incisions allow for optimal visualization [7].
- With the skin flaps retracted, the forearm fascia is incised longitudinally and the dome of the cyst identified and mobilized [7].
- Particular care should be taken to identify and protect the radial artery, which is frequently intimately attached to the wall of the ganglion and may even be completely encircled by the ganglion [7].
- Loupe magnification aids in this dissection [7].
- The pedicle is traced to the volar joint capsule (usually the scaphotrapezial or radiocarpal ligament) [7].
- The joint is opened and explored and the ganglion attachments are excised (approximately 3 ± 4 mm) [7].
- Once the ganglion has been excised, the surrounding tissues can be compressed digitally to rule out further mucin-filled pockets [7].
- If unidentified extensions are present, they must be excised [7].
- Hemostasis, wound lavage, and a simple skin closure (preferably subcuticular) complete the operation [7].
- Capsular closure is unnecessary and only delays early mobilization [7].
- A bulky bandage and elevation of the hand ensure early postoperative comfort [7].
- Motion of the wrist should begin within the first 2 weeks after surgery [7].
- Unexpected branches of the radial sensory or lateral antebrachial cutaneous nerves may be injured and lead to troublesome neuromas [7].
- Extensions of the routine incision into the carpal canal must avoid injury to the palmar cutaneous branch of the median nerve [7].
- Injuries to the radial artery can be repaired microscopically [7].
- Some authors recommend leaving a portion of the cyst wall attached to the artery to avoid arterial injury [7].
- Stiffness of the wrist is less common than with dorsal ganglions, but it can occur if early motion is not encouraged [7].
- Unpleasant scars are not an uncommon problem [7].
- The best indication for arthroscopic treatment of volar wrist ganglion is sessile type of volar wrist ganglion arising from the radiocarpal joint and centered on the proximal wrist crease [10].
- Mobile ganglia with long pedicle are poor candidates for arthroscopic surgery [10].
- Preoperative ultrasound scanning helps to confirm the articular origin and nature of the cystic mass [10].
- Arthroscopic drainage of a ganglion from the STT joint is feasible with the addition of new portals [10].
- The author prefers to perform arthroscopic volar wrist ganglionotomy under PSLA without the use of a tourniquet as this can help monitor any possible iatrogenic damage to the radial artery and its branches during the surgery [10].
- A wrist arthrogram can be performed immediately prior to the arthroscopic intervention or as a separate investigative procedure [10].
- The use of an intraoperative arthrogram of a ganglion as arising from the radiocarpal joint is described [10].
- Absence of demonstrable contrast filling the stalk with communication from the radiocarpal joint may preclude the use of the technique [10].
- 3 to 5 cc of nonionic contrast solution is admixed with 2% lidocaine and injected into the radiocarpal joint at the 3-4 portal site under fluoroscopic guidance [10].
- Typically, the stalk of the ganglion, and occasionally the cyst itself, can be identified at one of the volar radiocarpal ligament intervals [10].
- Ganglia arising from the interval between the RSC and the LRL ligament will show up at the more lateral aspect of the distal radius [10].
- Ganglia arising from the interval between the LRL and SRL ligaments will show up at a more central position of the distal radius [10].
- The relative position of the contrast-filling stalk can aid the identification of the true stalk during the actual arthroscopic procedure and hence facilitate subsequent decompression [10].
- As a rule, ganglia arising from the midcarpal joint or STT joint will not be revealed by arthrogram of the radiocarpal joint, unless one of the interosseous ligaments at the proximal carpal row is ruptured and creates a free communication between the radiocarpal and the midcarpal joint [10].
- For a right-handed surgeon operating on the right wrist, the scope entry site is typically 1-2, and working portal is 3-4 [10].
- For the left wrist, the sites are reversed [10].
- The outflow portal is 6U [10].
- Routine diagnostic arthroscopic examination of the radiocarpal joint is performed, followed by localization of the ganglion [10].
- This method is safer and more reliable for treating volar wrist ganglia [6].
- The arthroscopic resection of radiocarpal volar ganglia is a reasonable alternative to open excision with decreased postoperative morbidity, easy technique, and high rate of good results [31].
Other Locations and Considerations¶
- Dorsal wrist ganglions can be confused with carpal bosses, which are osteoarthritic spurs or prominences that develop at the base of the second or third carpometacarpal joints (or both) [18].
- A firm, bony, nonmobile, tender mass is visible and palpable at the base of the carpometacarpal joints, especially when the wrist is flexed [18].
- Radiologically, the mass is best visualized with the hand in 30 to 40 degrees of supination and 20 to 30 degrees of ulnar deviation (“carpal boss view”) [18].
- Bosses are more common in women, in the right hand, and between the third and fourth decades [18].
- The mass may be asymptomatic, or the patient may complain of considerable pain and aching [18].
- Every effort should be made to treat the carpal boss nonoperatively [18].
- Splinting, nonsteroidal antiinflammatory medications, and ultrasound-guided cortisone injections should be used or strongly considered prior to proceeding with surgery for carpal boss [18].
- The potential for persistent symptoms following surgery for carpal boss must be emphasized [18].
Complications¶
Recurrence¶
- Failure to identify and excise the pedicle attachment to the scapholunate ligament increases the likelihood of recurrence for dorsal wrist ganglions [1].
- Nine of 54 (16.7%) arthroscopic excisions resulted in cyst recurrence [19].
- Eight of 118 (6.8%) open excisions resulted in cyst recurrence [19].
- Routine midcarpal joint exploration during arthroscopic excision of dorsal wrist ganglions appeared to reduce recurrence at 1 year [9].
Nerve Injury¶
- Nerve injury in wrist arthroscopy typically affects the dorsal sensory branch of the radial or ulnar nerve and is related to portal placement or suture of the TFCC [21].
Vascular Injury¶
- The radial artery is frequently intimately attached to the wall of a volar ganglion and may be completely encircled by it [7].
- Injuries to the radial artery during volar ganglion excision can be repaired microscopically [7].
- Some authors recommend leaving a portion of the cyst wall attached to the radial artery to avoid arterial injury [7].
Pain and Stiffness¶
- Wrist stiffness is less common with volar ganglions than with dorsal ganglions but can occur if early motion is not encouraged [7].
- Wrist stiffness is an uncommon complication of wrist arthroscopy of uncertain etiology [21].
Other Complications¶
- Infection is an uncommon complication of wrist arthroscopy [21].
- ECU tendinitis may be related to portal placement or the suture knot after TFCC repair in wrist arthroscopy [21].
- Improper portal placement in wrist arthroscopy may result in tendon injury [21].
- Metacarpophalangeal joint pain caused by overdistraction is a transient complication of wrist arthroscopy [21].
- Unpleasant scars are not an uncommon problem following volar wrist ganglion excision [7].
Recovery¶
- Wrist motion should begin within the first 2 weeks after volar wrist ganglion excision surgery [7].
- A bulky bandage and elevation of the hand are used to ensure early postoperative comfort following volar wrist ganglion excision [7].
- Stiffness of the wrist is less common after volar wrist ganglion excision than after dorsal ganglion excision, but it can occur if early motion is not encouraged [7].
- In children aged <10 years, 69% to 79% of volar wrist ganglions display spontaneous regression within a span of 12-18 months when treated expectantly [8].
- Postoperative recovery of the wrist was rapid following an unusual carpometacpal fracture-dislocation, though extension of the fingers remained poor for over 3 months [35].
Key Evidence¶
- [L4] Pediatric ganglions of the hand have a greater rate of resolution than ganglions of the wrist. [2] (10.1016/j.jhsa.2023.07.002)
- [L4] Female patients who have preoperative pain around dorsal wrist ganglia were the most likely to have residual pain after surgery. [3] (10.1016/j.arthro.2013.04.002)
- [L4] The study concludes that routinely performing wrist radiography is not cost-effective in the evaluation and treatment decision-making process for patients with a wrist ganglion due to a low prevalence of therapeutically significant findings. [4] (10.1007/s11552-007-9032-8)
- [Paper] This method is safer and more reliable for treating volar wrist ganglia. [6] (10.1016/j.eats.2011.12.007)
- [L4] In children aged <10 years, ganglions mainly occur on the volar wrist and can be treated expectantly, with 69% to 79% displaying spontaneous regression within a span of 12-18 months. [8] (10.1016/j.jhsa.2021.12.015)
- [L3] Routine midcarpal joint exploration during arthroscopic excision of dorsal wrist ganglions appeared to reduce recurrence at 1 year without negatively impacting patient outcomes. [9] (10.1177/17531934251405730)
- [L4] There is no consensus within the literature regarding the best management of pediatric wrist ganglia, and no single treatment modality confers a particular advantage or disadvantage over another. [11] (10.1177/1558944720966716)
- [L4] Surgical excision of primary wrist ganglia significantly reduces patient symptoms with low recurrence rates and high patient satisfaction. [12] (10.1177/1753193411434376)
- [L3] The incidence of dorsal wrist ganglia was higher in the military compared with the civilian population. [13] (10.1016/j.jhsg.2020.08.001)
- [L2] Ganglions in pediatric populations, which most commonly affect the dorsal wrist, demonstrate a female predilection. [14] (10.1016/j.jhsa.2021.02.026)
- [L3] MRI scans provide relatively good reliability in establishing the diagnosis of an occult dorsal wrist ganglion, with a sensitivity of 83% when using intra-operative findings as the standard. [15] (10.1177/1753193408092041)
- [L4] The outcomes, recurrence, and complications rates after 4 years of follow-up presented in this study support the use of arthroscopy as a treatment for dorsal wrist ganglion. [16] (10.1177/1558944717743601)
- [L4] While observation and/or splinting will likely be helpful in resolution of a majority of pediatric hand and wrist ganglions, surgical excision is indicated for those that are symptomatic, do not resolve after approximately 2 months of observation and/or splinting, or recur. [17] (10.1007/s11552-008-9122-2)
- [L3] [19] (10.1177/15589447211003184)
- [L4] [22] (10.1016/j.jhsa.2015.05.025)
- [L5] The development of a trigger wrist is atypical, with multiple causes for its development. [24] (10.1177/15589447241284303)
- [L4] The proposed classification of ganglia helps minimize the area of resection required. [25] (10.1054/jhsb.2001.0620)
- [L4] Arthroscopic ganglionectomy through an intrafocal cystic portal is a safe and efficacious option for the treatment of painful wrist ganglia. [26] (10.1016/j.arthro.2009.08.021)
- [L4] In a child with a wrist ganglion, if the cyst ultimately resolved, it usually did so within 18 months. [29] (10.1016/j.jhsa.2019.10.032)
- [L1] The arthroscopic resection of radiocarpal volar ganglia is a reasonable alternative to open excision with decreased postoperative morbidity, easy technique, and high rate of good results. [31] (10.1080/02844310802210897)
- [L1] Open surgical excision offers significantly lower chance of recurrence compared with aspiration in the treatment of wrist ganglions. [32] (10.1016/j.jhsa.2014.12.014)
- [L4] It is important to ascertain the precise concerns of patients with ganglia and not assume that they attend the hand clinic with symptoms which justify surgical excision. [33] (10.1054/jhsb.2000.0504)
- [L5] Postoperatively recovery of the wrist was rapid, though extension of the fingers remained poor for over 3 months. [35] (10.1016/0020-1383(94)90161-9)
- [L3] [45] (10.1016/j.jhsa.2010.03.021)
- [Paper] Although aspiration with triamcinolone acetonide injection plus wrist immobilization is an alternative method, surgery was the most successful form of treatment when considering the cure rate of dorsal wrist ganglion. [46] (10.1007/s12593-011-0039-6)
- [L4] [50] (10.1016/s0749-0712(21)00020-2)
- [L4] MRI is an excellent diagnostic modality to evaluate rapidly growing upper extremity masses and distinguish ganglions from malignant processes. [54] (10.1007/s11552-007-9083-x)
- [L4] [58] (10.1055/s-0040-1716509)
- [L2] The systematic review and survey of Canadian hand surgeons reveal that hand surgeons are divided regarding the need to immobilize the wrist after dorsal wrist ganglion excision. [60] (10.1177/15589447211014631)
- [L4] [61] (10.1016/j.hcl.2013.08.020)
- [L4] CNNs can detect ganglion cysts in wrist MRI. [66] (10.1186/s12891-025-09011-1)
- [L4] [77] (10.2106/00004623-197254070-00009)
- [L4] [78] (10.1080/028443101750523267)
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